scholarly journals Human Derived Immortalized Dermal Papilla Cells With a Constant Expression of Testosterone Receptor

2020 ◽  
Vol 8 ◽  
Author(s):  
Tomokazu Fukuda ◽  
Kouhei Takahashi ◽  
Shin Takase ◽  
Ai Orimoto ◽  
Takahiro Eitsuka ◽  
...  
Keyword(s):  
Dermal Papilla ◽  
Dermal Papilla Cells ◽  
Constant Expression

scholarly journals Detecting the Mechanism behind the Transition from Fixed Two-Dimensional Patterned Sika Deer (Cervus nippon) Dermal Papilla Cells to Three-Dimensional Pattern

2021 ◽  
Vol 22 (9) ◽  
pp. 4715
Author(s):  
Guanning Wei ◽  
Hongmei Sun ◽  
Haijun Wei ◽  
Tao Qin ◽  
Yifeng Yang ◽  
...  
Keyword(s):  
Culture Condition ◽  
Sika Deer ◽  
Three Dimensional ◽  
Cervus Nippon ◽  
Dermal Papilla ◽  
Growth Patterns ◽  
The Self ◽  
Dermal Papilla Cells ◽  
Aggregative Behavior ◽  
Cell Pattern

The hair follicle dermal papilla is critical for hair generation and de novo regeneration. When cultured in vitro, dermal papilla cells from different species demonstrate two distinguishable growth patterns under the conventional culture condition: a self-aggregative three dimensional spheroidal (3D) cell pattern and a two dimensional (2D) monolayer cell pattern, correlating with different hair inducing properties. Whether the loss of self-aggregative behavior relates to species-specific differences or the improper culture condition remains unclear. Can the fixed 2D patterned dermal papilla cells recover the self-aggregative behavior and 3D pattern also remains undetected. Here, we successfully constructed the two growth patterns using sika deer (Cervus nippon) dermal papilla cells and proved it was the culture condition that determined the dermal papilla growth pattern. The two growth patterns could transit mutually as the culture condition was exchanged. The fixed 2D patterned sika deer dermal papilla cells could recover the self-aggregative behavior and transit back to 3D pattern, accompanied by the restoration of hair inducing capability when the culture condition was changed. In addition, the global gene expressions during the transition from 2D pattern to 3D pattern were compared to detect the potential regulating genes and pathways involved in the recovery of 3D pattern and hair inducing capability.

scholarly journals Combinatorial expression of cell cycle regulators is more suitable for immortalization than oncogenic methods in dermal papilla cells

iScience ◽  
2021 ◽  
Vol 24 (1) ◽  
pp. 101929
Author(s):  
Tomokazu Fukuda ◽  
Kai Furuya ◽  
Kouhei Takahashi ◽  
Ai Orimoto ◽  
Eriko Sugano ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Dermal Papilla ◽  
Cell Cycle Regulators ◽  
Dermal Papilla Cells ◽  
Combinatorial Expression

URB expression in human dermal papilla cells

2005 ◽  
Vol 39 (2) ◽  
pp. 128-130 ◽  
Author(s):  
So-Young Cha ◽  
Young Kwan Sung ◽  
Sanguk Im ◽  
Mi Hee Kwack ◽  
Moon Kyu Kim ◽  
...  
Keyword(s):  
Dermal Papilla ◽  
Dermal Papilla Cells

Immortalization of Dermal Papilla Cells by Viral Oncogenes

2006 ◽  
Vol 642 (1) ◽  
pp. 439-441 ◽  
Author(s):  
SUSAN A. BAYLEY ◽  
AMANDA J. STONES ◽  
WENDY FILSELL
Keyword(s):  
Dermal Papilla ◽  
Dermal Papilla Cells ◽  
Viral Oncogenes

Effects of glucocorticoid on human dermal papilla cells in vitro

2013 ◽  
Vol 135 ◽  
pp. 24-29 ◽  
Author(s):  
Soon-Jin Choi ◽  
A-Ri Cho ◽  
Seong-Jin Jo ◽  
Sungjoo Tommy Hwang ◽  
Kyu Han Kim ◽  
...  
Keyword(s):  
Dermal Papilla ◽  
Dermal Papilla Cells
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