scholarly journals More Favorable Palmitic Acid Over Palmitoleic Acid Modification of Wnt3 Ensures Its Localization and Activity in Plasma Membrane Domains

2019 ◽  
Vol 7 ◽  
Author(s):  
Yagmur Azbazdar ◽  
Ozgun Ozalp ◽  
Erdinc Sezgin ◽  
Sapthaswaran Veerapathiran ◽  
Anna L. Duncan ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Palmitic Acid ◽  
Palmitoleic Acid ◽  
Membrane Domains ◽  
Acid Modification ◽  
Plasma Membrane Domains

scholarly journals Rapid Nonvesicular Transport of Sterol between the Plasma Membrane Domains of Polarized Hepatic Cells

2002 ◽  
Vol 277 (33) ◽  
pp. 30325-30336
Author(s):  
Daniel Wüstner ◽  
Andreas Herrmann ◽  
Mingming Hao ◽  
Frederick R. Maxfield
Keyword(s):  
Plasma Membrane ◽  
Membrane Domains ◽  
Hepatic Cells ◽  
Plasma Membrane Domains

scholarly journals Synergistic Assembly of Linker for Activation of T Cells Signaling Protein Complexes in T Cell Plasma Membrane Domains

2003 ◽  
Vol 278 (22) ◽  
pp. 20389-20394 ◽  
Author(s):  
Lorian C. Hartgroves ◽  
Joseph Lin ◽  
Hanno Langen ◽  
Tobias Zech ◽  
Arthur Weiss ◽  
...  
Keyword(s):  
T Cells ◽  
Plasma Membrane ◽  
T Cell ◽  
Protein Complexes ◽  
Membrane Domains ◽  
Cell Plasma Membrane ◽  
Signaling Protein ◽  
Cell Plasma ◽  
Plasma Membrane Domains

Molecular events in the organization of renal tubular epithelium: from nephrogenesis to regeneration

1989 ◽  
Vol 257 (6) ◽  
pp. F913-F924 ◽  
Author(s):  
R. Bacallao ◽  
L. G. Fine
Keyword(s):  
Plasma Membrane ◽  
Spatial Organization ◽  
Cell Interaction ◽  
Acute Injury ◽  
External Signal ◽  
Renal Tubular Cell ◽  
Membrane Domains ◽  
Sequence Of Events ◽  
Plasma Membrane Domains ◽  
Renal Tubular

Information from studies of embryonic nephrons and established renal tubular cell lines in culture can be integrated to derive a picture of how the renal tubule develops and regenerates after acute injury. During development, the formation of a morphologically polarized epithelium from committed nephric mesenchymal cells requires an external signal for mitogenesis and differentiation. Polypeptide growth factors, in some cases mediated through oncogene expression, act in an autocrine or paracrine fashion to stimulate the production of extracellular matrix proteins that probably provide the earliest orientation signal for the cell. Interaction of these proteins with cell surface receptors leads to early organization of the cytoskeletal actin network, which is the major scaffolding for further differentiation and for definition of plasma membrane domains. The formation of cell-cell contacts via specialized adhesion molecules integrates the epithelium into a polarized monolayer and maintains its fence function, i.e., separation of plasma membrane domains. Microtubules probably participate in the delivery of vesicles to specific plasma membrane domains and in the spatial organization of intracellular organelles. Following acute renal injury, this sequence of events appears to be reversed, resulting in partial or complete loss of differentiated features. Regeneration seems to follow the same pattern of sequential differentiation steps as nephrogenesis. The integrity of the epithelium is restored by reestablishing only those stages of differentiation that have been lost. Where cell death occurs, mitogenesis in adjacent cells restores the continuity of the epithelium and the entire sequence of differentiation events is initiated in the newly generated cells.

scholarly journals Fence Model for Dynamic Exchange and Retention of GLUT4 in Plasma Membrane Domains

2012 ◽  
Vol 102 (3) ◽  
pp. 320a-321a
Author(s):  
Vladimir A. Lizunov ◽  
Karin Stenkula ◽  
Samuel Cushman ◽  
Joshua Zimmerberg
Keyword(s):  
Plasma Membrane ◽  
Membrane Domains ◽  
Plasma Membrane Domains ◽  
Dynamic Exchange
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