scholarly journals How Does Cost-Sharing Impact Spending Growth and Cost-Effective Treatments? Evidence from Deductibles

2020 ◽  
Author(s):  
Claudio Lucarelli ◽  
Molly Frean ◽  
Aliza Gordon ◽  
Lynn Hua ◽  
Mark Pauly
Keyword(s):  
Cost Sharing ◽  
Cost Effective ◽  
Spending Growth ◽  
Effective Treatments

scholarly journals How Does Cost-Sharing Impact Spending Growth and Cost-Effective Treatments? Evidence from Deductibles

2020 ◽  
Author(s):  
Claudio Lucarelli ◽  
Molly Frean ◽  
Aliza Gordon ◽  
Lynn Hua ◽  
Mark Pauly
Keyword(s):  
Cost Sharing ◽  
Cost Effective ◽  
Spending Growth ◽  
Effective Treatments

Evidence of cost-effective treatments for depression: a systematic review

2005 ◽  
Vol 84 (1) ◽  
pp. 1-13 ◽  
Author(s):  
Barbara Barrett ◽  
Sarah Byford ◽  
Martin Knapp
Keyword(s):  
Systematic Review ◽  
Cost Effective ◽  
Effective Treatments

scholarly journals Hepatitis C Variability, Patterns of Resistance, and Impact on Therapy

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Cristina Simona Strahotin ◽  
Michael Babich
Keyword(s):  
Hepatitis C ◽  
Antiviral Agents ◽  
Cost Effective ◽  
Standard Of Care ◽  
The United States ◽  
Resistance Mechanisms ◽  
Cost Effective Method ◽  
New Treatments ◽  
Cure Rates ◽  
Effective Treatments

Hepatitis C (HCV), a leading cause of chronic liver disease, cirrhosis, and hepatocellular carcinoma, is the most common indication for liver transplantation in the United States. Although annual incidence of infection has declined since the 1980s, aging of the currently infected population is expected to result in an increase in HCV burden. HCV is prone to develop resistance to antiviral drugs, and despite considerable efforts to understand the virus for effective treatments, our knowledge remains incomplete. This paper reviews HCV resistance mechanisms, the traditional treatment with and the new standard of care for hepatitis C treatment. Although these new treatments remain PEG-IFN-α- and ribavirin-based, they add one of the newly FDA approved direct antiviral agents, telaprevir or boceprevir. This new “triple therapy” has resulted in greater viral cure rates, although treatment failure remains a possibility. The future may belong to nucleoside/nucleotide analogues, non-nucleoside RNA-dependent RNA polymerase inhibitors, or cyclophilin inhibitors, and the treatment of HCV may ultimately parallel that of HIV. However, research should focus not only on effective treatments, but also on the development of a HCV vaccine, as this may prove to be the most cost-effective method of eradicating this disease.

scholarly journals Near-Equivalence: Generating Evidence to Support Alternative Cost-Effective Treatments

2021 ◽  
pp. JCO.20.02768
Author(s):  
Ian F. Tannock ◽  
Mark J. Ratain ◽  
Daniel A. Goldstein ◽  
Allen S. Lichter ◽  
Gary L. Rosner ◽  
...  
Keyword(s):  
Cost Effective ◽  
Effective Treatments
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