scholarly journals 1α-Hydroxycholecalciferol improves the growth performance and up-regulates the mRNA expression of vitamin D receptor in the small intestine and kidney of broiler chickens

2018 ◽  
Vol 97 (4) ◽  
pp. 1263-1270
Author(s):  
J.C. Han ◽  
J.G. Wang ◽  
G.H. Chen ◽  
J.L. Zhang ◽  
N. Zhang ◽  
...  
Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 399
Author(s):  
Magdalena Krauze ◽  
Monika Cendrowska-Pinkosz ◽  
Paulius Matuseviĉius ◽  
Anna Stępniowska ◽  
Paweł Jurczak ◽  
...  

It was postulated that a phytobiotic preparation containing cinnamon oil and citric acid added to drinking water for chickens in a suitable amount and for a suitable time would beneficially modify the microbiota composition and morphology of the small intestine, thereby improving immunity and growth performance without inducing metabolic disorders. The aim of the study was to establish the dosage and time of administration of such a phytobiotic that would have the most beneficial effect on the intestinal histology and microbiota, production results, and immune and metabolic status of broiler chickens. The experiment was carried out on 980 one-day-old male chickens until the age of 42 days. The chickens were assigned to seven experimental groups of 140 birds each (seven replications of 20 individuals each). The control group (G-C) did not receive the phytobiotic. Groups CT-0.05, CT-0.1, and CT-0.25 received the phytobiotic in their drinking water in the amount of 0.05, 0.1, and 0.2 mL/L, respectively, at days 1–42 of life (continuous application, CT). The birds in groups PT-0.05, PT-0.5, and PT-0.25 received the phytobiotic in the same amounts, but only at days 1–7, 15–21, and 29–35 of life (periodic application, PT). Selected antioxidant and biochemical parameters were determined in the blood of the chickens, as well as parameters of immune status and redox status. The morphology of the intestinal epithelium, composition of the microbiome, and production parameters of chickens receiving the phytobiotic in their drinking water were determined as well. The addition of a phytobiotic containing cinnamon oil and citric acid to the drinking water of broiler chickens at a suitable dosage and for a suitable time can beneficially modify the microbiome composition and morphometry of the small intestine (total number of fungi p < 0.001, total number of aerobic bacteria p < 0.001; and total number of coliform bacteria p < 0.001 was decreased) improving the immunity and growth performance of the chickens (there occurred a villi lengthening p = 0.002 and crypts deepening p = 0.003). Among the three tested dosages (0.05, 0.1, and 0.25 mL/L of water) of the preparation containing cinnamon oil, the dosage of 0.25 mL/L of water administered for 42 days proved to be most beneficial. Chickens receiving the phytobiotic in the amount of 0.25 mL/L had better growth performance, which was linked to the beneficial effect of the preparation on the microbiome of the small intestine, metabolism (the HDL level p = 0.017 was increased; and a decreased level of total cholesterol (TC) p = 0.018 and nonesterified fatty acids (NEFA) p = 0.007, LDL p = 0.041, as well as triacylglycerols (TAG) p = 0.014), and immune (the level of lysozyme p = 0.041 was increased, as well as the percentage of phagocytic cells p = 0.034, phagocytosis index p = 0.038, and Ig-A level p = 0.031) and antioxidant system (the level of LOOH p < 0.001, MDA p = 0.002, and the activity of Catalase (CAT) p < 0.001 were decreased, but the level of ferric reducing ability of plasma (FRAP) p = 0.029, glutathione p = 0.045 and vitamin C p = 0.021 were increased).


1990 ◽  
Vol 14 ◽  
pp. 55
Author(s):  
G PAATERO ◽  
T TRYDAL ◽  
J LILLEHAUG ◽  
K KARLSTEDT

PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e4435 ◽  
Author(s):  
Lin Yuan ◽  
Wanli Li ◽  
Qianqian Huo ◽  
Chenhong Du ◽  
Zhixiang Wang ◽  
...  

This study investigated the effects of xylo-oligosaccharide (XOS) and flavomycin (FLA) on the performance and immune function of broiler chickens. A total of 150 ArborAcres broilers were randomly divided into three groups and fed for six weeks from one day of age in cascade cages. The diets of each test group were (1) a basal diet, (2) the basal diet supplemented with 2 mg/kg FLA, and (3) the basal diet supplemented with 2 mg/kg XOS. At 21 and 42 days, the growth performance index values and short-chain fatty acid (SCFA) concentrations in the cecum were quantified. Furthermore, immunoglobulin G (IgG) and plasma interleukin 2 (IL-2) as well as mRNA expression of LPS-Induced TNF-alpha Factor (LITAF), Toll-like receptor-5 (TLR5) and interferon gamma (IFNγ) in the jejunum were quantified. The results showed that administration of XOS or FLA to chickens significantly improved the average daily gain. Supplementation with XOS increased acetate and butyrate in the cecum, while FLA supplementation increased propionate in the cecum. An increase in plasma IgG was observed in XOS-fed 21-day-old broilers, but FLA supplementation decreased IgG in the plasma of 42-day-old broilers and increased plasma IL-2. Furthermore, FLA or XOS supplementation downregulated mRNA expression of IFNγ, LITAF and TLR5. The above data suggest that addition of XOS and FLA to the diet could improve the growth performance of broilers and reduce the expression of cytokine genes by stimulating SCFA.


2015 ◽  
Vol 153 ◽  
pp. 29-38 ◽  
Author(s):  
Hui Jin ◽  
Yang Huang ◽  
Guang Jin ◽  
Yanrong Xue ◽  
Xiaowei Qin ◽  
...  

1996 ◽  
Vol 106 (4) ◽  
pp. 637-641 ◽  
Author(s):  
Ming L. Chen ◽  
Alberto Perez ◽  
Deepak K. Sanan ◽  
Gerhard Heinrich ◽  
Tai C. Chen ◽  
...  

1999 ◽  
Vol 14 (2) ◽  
pp. 240-247 ◽  
Author(s):  
Hironori Yamamoto ◽  
Ken-Ichi Miyamoto ◽  
Bailing Li ◽  
Yutaka Taketani ◽  
Mutsuko Kitano ◽  
...  

2020 ◽  
Vol 46 (4) ◽  
pp. 89-100
Author(s):  
K. T. Orayaga ◽  
A. C. Okolie ◽  
N. B. Asanka ◽  
S. Idede

A number of alternative feedstuff that are affordable and profitable for use in developing countries for animal feeding have been identified and reported. However, some of these alternative feedstuff have low nutrient density, and some with high nutrient density are difficult to process and or preserve. However, it is reported that two different alternative feedstuff could be mixed to improve the nutrient density of the mixture, and be preserved better at the same time. Mango fruit reject pulp has high energy content but cannot be easily sundried and preserved alone, except a carrier is involved. Four (4) experiments were conducted to determine the proximate composition and energy content of mango fruit reject pulp-maize offal mix meal (MFRP-MO); effects of MFRP-MO on growth performance and economics of productions for starter and finisher broiler chickens, carcass characteristics, internal organs and gastro-intestinal tract (GIT) morphometry of finisher broiler chickens. Mango fruit rejects pulp-maize offal mix meal (MFRP-MO) partially replaced maize at 0, 20, 40, 60, and 80% respectively to produce diets coded T1 (0%), T2 (20%), T3 (40%), T4 (60%), T5 (80%), and T1(0%). One hundred and eighty (180) day-old Marshall broiler chicks were grouped into five, with each group replicated three times and a replicate contained 12 birds in completely randomized design (CRD); which were exposed to the diets in a feeding trial that lasted for 28 and 49 days for starter and finisher phases respectively. MFRP-MO contained 9.63% CP, 68.38% NFE and 3320. 41kcal/kg ME. Results of mean growth performance parameters for starter and finisher phases declined from 40% and 20% MFRPMO respectively on parameters including final weight, daily weight gain and FCR. Economic indices were better at 80% MFRP-MO mix replacement of maize; the cost per kg weight gain steadily declined. Percentage feed costs were 32.36 to 39.92% and 53.50 to 62.75% for starter and finisher respectively. The dress percent, major carcass cuts and internal organs were not significantly different. With the exception of large intestine length, which was not significantly different (p<0.05), caeca and small intestine varied in opposite directions: small intestine decreased, while caeca increased as MFRP-MO mix increased. It was concluded that 20% replacement of maize by MFRP-MO mix was optimal for both starter and finishing broiler chickens' growth but 60% was more economical and 60% MFRP-MO mix was recommended.


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