scholarly journals Effects of yeast cell wall-derived mannan-oligosaccharides on jejunal gene expression in young broiler chickens

2012 ◽  
Vol 91 (7) ◽  
pp. 1660-1669 ◽  
Author(s):  
R. Xiao ◽  
R.F. Power ◽  
D. Mallonee ◽  
K. Routt ◽  
L. Spangler ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cell Wall ◽  
Yeast Cell ◽  
Broiler Chickens ◽  
Yeast Cell Wall ◽  
Mannan Oligosaccharides

scholarly journals Feeding of yeast cell wall extracts during a necrotic enteritis challenge enhances cell growth, survival and immune signaling in the jejunum of broiler chickens

2020 ◽  
Vol 99 (6) ◽  
pp. 2955-2966
Author(s):  
Casey N. Johnson ◽  
Mohammed M. Hashim ◽  
Christopher A. Bailey ◽  
James A. Byrd ◽  
Michael H. Kogut ◽  
...  
Keyword(s):  
Cell Wall ◽  
Cell Growth ◽  
Yeast Cell ◽  
Broiler Chickens ◽  
Yeast Cell Wall ◽  
Necrotic Enteritis ◽  
Immune Signaling

Dietary hydrolysed yeast cell wall extract is comparable to antibiotics in the control of subclinical necrotic enteritis in broiler chickens

2019 ◽  
Vol 60 (6) ◽  
pp. 757-765
Author(s):  
E. U. Ahiwe ◽  
E. P. Chang’a ◽  
M. E. Abdallh ◽  
M. Al-Qahtani ◽  
S. K. Kheravii ◽  
...  
Keyword(s):  
Cell Wall ◽  
Yeast Cell ◽  
Broiler Chickens ◽  
Yeast Cell Wall ◽  
Necrotic Enteritis ◽  
Cell Wall Extract

scholarly journals PSXIV-42 Late-Breaking: Effects of yeast cell wall product on growth performance, immune responses, and gene expression of tight junction proteins of weaned pigs

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 333-334
Author(s):  
Hyunjin Kyoung ◽  
Myungwoo Cho ◽  
Hanbae Lee ◽  
Sangwoo Park ◽  
Joowon Kang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cell Wall ◽  
Immune Responses ◽  
Tight Junction ◽  
Yeast Cell ◽  
Growth Performance ◽  
Experimental Period ◽  
Yeast Cell Wall ◽  
Weaned Pigs ◽  
Tnf Α

Abstract The study was conducted to investigate effects of yeast cell wall product on growth performance, immune responses, and gene expression of tight junction proteins of weaned pigs. A total of 112 weaned pigs (7.98 ± 0.43 kg BW) were randomly assigned to 2 dietary treatments (8 pigs/pen; 7 replicates/treatments) for 4 weeks in a randomized complete block design (block = BW). Dietary treatments were 1) a commercial basal nursery diet (CON) and 2) CON + 0.05% yeast cell wall product (YCW, EasyBio Inc., Seoul, Korea). Blood was collected from one randomly selected pig per pen on d 0, 7, and 14 after weaning. The randomly selected one pig per replicate was euthanized to collect ileum tissue samples at the end of the experimental period. Measurements were growth performance, number of white blood cells (WBC) by an automated hematology analyzer calibrated for porcine blood, cortisol, tumor necrosis factor-α (TNF-α), transforming growth factor-β1, interleukin-1β (IL-1β), and interleukin-6 (IL-6) by the ELISA, and gene expression of tight junction in ileum tissues. Data were analyzed using the PROC GLM procedure of SAS. The statistical model for every measurement included dietary effect and BW as a covariate. Pigs fed YCW had higher (P < 0.10) ADG than those fed CON during overall experimental period. Pigs fed YCW had lower WBC on d 14 (P < 0.10), TNF-α on d 7 (P < 0.10), and decreased IL-1β on d 14 (P < 0.05) than those fed CON. In addition, The YCW increased (P < 0.05) expression of Claudin family, Occludin, Muc1, INF-α, and IL-6, but decreased (P < 0.05) expression of TNF-α genes in the ileum tissues compared with CON. In conclusion, addition of yeast cell wall product in the nursery diet improved growth performance and gut health and modified immune responses of weaned pigs.

scholarly journals Comprehensive Evaluation of the Efficiency of Yeast Cell Wall Extract to Adsorb Ochratoxin A and Mitigate Accumulation of the Toxin in Broiler Chickens

Toxins ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 37 ◽  
Author(s):  
Suvi Vartiainen ◽  
Alexandros Yiannikouris ◽  
Juha Apajalahti ◽  
Colm A. Moran
Keyword(s):  
Cell Wall ◽  
Yeast Cell ◽  
Ochratoxin A ◽  
Broiler Chickens ◽  
Animal Feed ◽  
Animal Health ◽  
Yeast Cell Wall ◽  
In Vivo Model

Ochratoxin A (OTA) is a common mycotoxin contaminant in animal feed. When absorbed from the gastrointestinal tract, OTA has a propensity for pathological effects on animal health and deposition in animal tissues. In this study, the potential of yeast cell wall extracts (YCWE) to adsorb OTA was evaluated using an in vitro method in which consecutive animal digestion events were simulated. Low pH markedly increased OTA binding to YCWE, which was reversed with a pH increased to 6.5. Overall, in vitro analysis revealed that 30% of OTA was adsorbed to YCWE. Additional computational molecular modelling revealed that change in pH alters the OTA charge and modulates the interaction with the YCWE β-d-glucans. The effectiveness of YCWE was tested in a 14-day broiler chicken trial. Birds were subjected to five dietary treatments; with and without OTA, and OTA combined with YCWE at three dosages. At the end of the trial, liver OTA deposition was evaluated. Data showed a decrease of up to 30% in OTA deposits in the liver of broilers fed both OTA and YCWE. In the case of OTA, a tight correlation between the mitigation efficacy of YCWE between in vitro and in vivo model could be observed.

scholarly journals Toxicity of Mycotoxins from Contaminated Corn with or without Yeast Cell Wall Adsorbent on Broiler Chickens

2015 ◽  
Vol 29 (5) ◽  
pp. 674-680 ◽  
Author(s):  
Q. H. Shang ◽  
Z. B. Yang ◽  
W. R. Yang ◽  
Z. Li ◽  
G. G. Zhang ◽  
...  
Keyword(s):  
Cell Wall ◽  
Yeast Cell ◽  
Broiler Chickens ◽  
Yeast Cell Wall

scholarly journals Mitigation of AFB1-Related Toxic Damage to the Intestinal Epithelium in Broiler Chickens Consumed a Yeast Cell Wall Fraction

2021 ◽  
Vol 8 ◽  
Author(s):  
Juan Omar Hernández-Ramírez ◽  
Rubén Merino-Guzmán ◽  
Guillermo Téllez-Isaías ◽  
Alma Vázquez-Durán ◽  
Abraham Méndez-Albores
Keyword(s):  
Cell Wall ◽  
Yeast Cell ◽  
Intestinal Epithelium ◽  
Broiler Chickens ◽  
Negative Impact ◽  
Yeast Cell Wall ◽  
Point Of Zero Charge ◽  
Control Group ◽  
Cell Wall Fraction ◽  
Gut Health

In vivo experiments were conducted to evaluate the effectiveness of a yeast cell wall fraction (YCW) to reduce the negative impact of aflatoxin B1 (AFB1) to the intestinal epithelium in broiler chickens. Zeta potential (ζ-potential), point of zero charge (pHpzc), Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM) techniques were used to characterize the YCW. Two hundred one-day-old male Ross 308 broiler chickens were randomly allocated into four treatments: (1) control, chickens fed an AFB1-free diet; (2) AF, chickens feed an AFB1-contaminated diet (500 ng AFB1/g); (3) YCW, chickens fed an AFB1-free diet + 0.05% YCW; and (4) AF + YCW, chickens fed an AFB1-contaminated diet (500 ng AFB1/g) + 0.05% YCW. At the end of the 21-day feeding period, fluorescein isothiocyanate dextran (FITC-d) was administered to chicks by oral gavage to evaluate gastrointestinal leakage. Blood and duodenum samples were collected to assess serum biochemistry and histomorphology, respectively. Compared to the control group, chicks of the AF group significantly diminished weight gain (WG) and average daily feed intake (ADFI), and increased feed conversion ratio (FCR), mortality rate (MR), and intestinal lesion scores (p < 0.05). Alterations in some serum biochemical parameters, and damage to the intestinal integrity were also evident in the AF-intoxicated birds. YCW supplementation improved WG and FCR and increased villus height, villus area, crypt depth, and the number of goblet cells in villi. The effects of YCW on growth performance were not significant in chicks of the AF + YCW group; however, the treatment decreased MR and significantly ameliorated some biochemical and histomorphological alterations. The beneficial effect of YCW was more evident in promoting gut health since chickens of the AF + YCW group presented a significant reduction in serum FITC-d concentration. This positive effect was mainly related to the changes in negative charges of YCW due to changes in pH, the net negative surface charge above the pHpzc, the higher quantities of negative charged functional groups on the YCW surface, and its ability to form large aggregates. From these results, it can be concluded that YCW at low supplementation level can partially protect broilers' intestinal health from chronic exposure to AFB1.

Extraction and Deproteinization of Mannan Oligosaccharides

2010 ◽  
Vol 65 (5-6) ◽  
pp. 387-390 ◽  
Author(s):  
Gang Huang ◽  
Qin Yang ◽  
Zhong B. Wang
Keyword(s):  
Cell Wall ◽  
Hydrochloric Acid ◽  
Yeast Cell ◽  
Trichloroacetic Acid ◽  
The Other ◽  
Yeast Cell Wall ◽  
Mannan Oligosaccharide ◽  
Acid Method ◽  
Mannan Oligosaccharides

Extraction of mannan oligosaccharides from the yeast cell wall and methods of deproteinization were studied. We extracted crude mannan oligosaccharides by the dilute alkali- Sevage method. The percentages of deproteinization and mannan oligosaccharide loss were compared as indexes using the Sevage method, trichloroacetic acid method, and hydrochloric acid method. The results showed that the hydrochloric acid method exhibited the highest percentage of deproteinization, but only a little higher percentage of mannan oligosaccharide loss than the other two methods.

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