scholarly journals Quantitative trait loci associated with the humoral innate immune response in chickens were confirmed in a cross between Green-Legged Partridgelike and White Leghorn

2011 ◽  
Vol 90 (9) ◽  
pp. 1909-1915 ◽  
Author(s):  
A. Sławińska ◽  
A. Witkowski ◽  
M. Nieuwland ◽  
G. Minozzi ◽  
M. Bednarczyk ◽  
...  
Keyword(s):  
Immune Response ◽  
Quantitative Trait Loci ◽  
Innate Immune Response ◽  
Quantitative Trait ◽  
Innate Immune ◽  
White Leghorn ◽  
Trait Loci

Mapping quantitative trait loci for innate immune response in the pig

2011 ◽  
Vol 38 (2) ◽  
pp. 121-131 ◽  
Author(s):  
M. J. Uddin ◽  
M. U. Cinar ◽  
C. Große-Brinkhaus ◽  
D. Tesfaye ◽  
E. Tholen ◽  
...  
Keyword(s):  
Immune Response ◽  
Quantitative Trait Loci ◽  
Innate Immune Response ◽  
Quantitative Trait ◽  
Innate Immune ◽  
Trait Loci

scholarly journals Principal component analysis of quantitative trait loci for immune response to adenovirus in mice

Hereditas ◽  
2006 ◽  
Vol 143 (2006) ◽  
pp. 189-197 ◽  
Author(s):  
Solomon K. Musani ◽  
Huang-Ge Zhang ◽  
Hui-Chen Hsu ◽  
Nengjun Yi ◽  
Bernard S. Gorman ◽  
...  
Keyword(s):  
Principal Component Analysis ◽  
Immune Response ◽  
Quantitative Trait Loci ◽  
Quantitative Trait ◽  
Principal Component ◽  
Component Analysis ◽  
Trait Loci

scholarly journals Genome-Wide Association Study in Mexican Holstein Cattle Reveals Novel Quantitative Trait Loci Regions and Confirms Mapped Loci for Resistance to Bovine Tuberculosis

Animals ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. 636 ◽  
Author(s):  
Sara González-Ruiz ◽  
Maria G. Strillacci ◽  
Marina Durán-Aguilar ◽  
Germinal J. Cantó-Alarcón ◽  
Sara E. Herrera-Rodríguez ◽  
...  
Keyword(s):  
Immune Response ◽  
Quantitative Trait Loci ◽  
Dairy Cattle ◽  
Quantitative Trait ◽  
Bovine Tuberculosis ◽  
Genome Wide Association ◽  
Economic Losses ◽  
Genome Wide ◽  
Trait Loci ◽  
Mycobacterium Spp

Bovine tuberculosis (bTB) is a disease of cattle that represents a risk to public health and causes severe economic losses to the livestock industry. Recently, genetic studies, like genome-wide association studies (GWAS) have greatly improved the investigation of complex diseases identifying thousands of disease-associated genomic variants. Here, we present evidence of genetic variants associated with resistance to TB in Mexican dairy cattle using a case-control approach with a selective DNA pooling experimental design. A total of 154 QTLRs (quantitative trait loci regions) at 10% PFP (proportion of false positives), 42 at 5% PFP and 5 at 1% PFP have been identified, which harbored 172 annotated genes. On BTA13, five new QTLRs were identified in the MACROD2 and KIF16B genes, supporting their involvement in resistance to bTB. Six QTLRs harbor seven annotated genes that have been previously reported as involved in immune response against Mycobacterium spp: BTA (Bos taurus autosome) 1 (CD80), BTA3 (CTSS), BTA 3 (FCGR1A), BTA 23 (HFE), BTA 25 (IL21R), and BTA 29 (ANO9 and SIGIRR). We identified novel QTLRs harboring genes involved in Mycobacterium spp. immune response. This is a first screening for resistance to TB infection on Mexican dairy cattle based on a dense SNP (Single Nucleotide Polymorphism) chip.

scholarly journals Quantitative trait loci for variation in immune response to a Foot-and-Mouth Disease virus peptide

BMC Genetics ◽  
2010 ◽  
Vol 11 (1) ◽  
pp. 107 ◽  
Author(s):  
Richard J Leach ◽  
Susan C Craigmile ◽  
Sara A Knott ◽  
John L Williams ◽  
Elizabeth J Glass
Keyword(s):  
Immune Response ◽  
Quantitative Trait Loci ◽  
Disease Virus ◽  
Quantitative Trait ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Mouth Disease Virus ◽  
Trait Loci ◽  
Foot And Mouth
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