scholarly journals Effects of Chick Age and Ingestion of Ascorbic Acid by the Dam on Plasma Cholesterol Levels

1972 ◽  
Vol 51 (6) ◽  
pp. 2108-2110 ◽  
Author(s):  
Cheryl F. Nockels
Keyword(s):  
Ascorbic Acid ◽  
Plasma Cholesterol ◽  
Cholesterol Levels

scholarly journals Lipid-lowering Activity of Natural and Semi-Synthetic Sterols and Stanols

2015 ◽  
Vol 18 (4) ◽  
pp. 344 ◽  
Author(s):  
Dhiaa A Taha ◽  
Ellen K Wasan ◽  
Kishor M Wasan ◽  
Pavel Gershkovich
Keyword(s):  
Ascorbic Acid ◽  
Animal Studies ◽  
Molecular Mechanisms ◽  
Plasma Cholesterol ◽  
Plant Sterols ◽  
Water Soluble ◽  
Lipid Lowering ◽  
Cholesterol Lowering ◽  
Cholesterol Levels ◽  
Lowering Activity

Consumption of plant sterols/ stanols has long been demonstrated to reduce plasma cholesterol levels. The objective of this review is to demonstrate the lipid-lowering activity and anti-atherogenic effects of natural and semi-synthetic plant sterols/ stanols based on evidence from cell-culture studies, animal studies and clinical trials. Additionally, this review highlights certain molecular mechanisms by which plant sterols/ stanols lower plasma cholesterol levels with a special emphasis on factors that affect the cholesterol-lowering activity of plant sterols/stanols. The crystalline nature and the poor oil solubility of these natural products could be important factors that limit their cholesterol-lowering efficiency. Several attempts have been made to improve the cholesterol-lowering activity by enhancing the bioavailability of crystalline sterols and stanols. Approaches involved reduction of the crystal size and/or esterification with fatty acids from vegetable or fish oils. However, the most promising approach in this context is the chemical modification of plant sterols /stanols into water soluble disodium ascorbyl phytostanyl phosphates analogue by esterification with ascorbic acid. This novel semi-synthetic stanol derivative has improved efficacy over natural plant sterols/ stanols and can provide additional benefits by combining the cholesterol-lowering properties of plant stanols with the antioxidant potential of ascorbic acid. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.

Effect of Dietary Ascorbic Acid on Performance and Plasma Cholesterol Levels of Growing Swine

1970 ◽  
Vol 31 (1) ◽  
pp. 63-66 ◽  
Author(s):  
G. L. Cromwell ◽  
V. W. Hays ◽  
J. R. Oveefield
Keyword(s):  
Ascorbic Acid ◽  
Plasma Cholesterol ◽  
Cholesterol Levels

Plasma cholesterol levels in free-ranging macaques compared with captive macaques and humans

Primates ◽  
2000 ◽  
Vol 41 (3) ◽  
pp. 299-309 ◽  
Author(s):  
Akiko Takenaka ◽  
Yuko Matsumoto ◽  
Aika Nagaya ◽  
Kunio Watanabe ◽  
Shunji Goto ◽  
...  
Keyword(s):  
Plasma Cholesterol ◽  
Cholesterol Levels ◽  
Free Ranging

scholarly journals Hyodeoxycholic acid efficiently suppresses atherosclerosis formation and plasma cholesterol levels in mice

2001 ◽  
Vol 42 (8) ◽  
pp. 1250-1256 ◽  
Author(s):  
Ephraim Sehayek ◽  
Jennie G. Ono ◽  
Elizabeth M. Duncan ◽  
Ashok K. Batta ◽  
Gerald Salen ◽  
...  
Keyword(s):  
Plasma Cholesterol ◽  
Cholesterol Levels ◽  
Hyodeoxycholic Acid

scholarly journals Gestational Diabetes Mellitus Treatment Schemes Modify Maternal Plasma Cholesterol Levels Dependent to Women´s Weight: Possible Impact on Feto-Placental Vascular Function

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 506 ◽  
Author(s):  
Susana Contreras-Duarte ◽  
Lorena Carvajal ◽  
María Jesús Garchitorena ◽  
Mario Subiabre ◽  
Bárbara Fuenzalida ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Vascular Function ◽  
Plasma Cholesterol ◽  
Umbilical Vein ◽  
Maternal Plasma ◽  
Maternal Weight ◽  
Cholesterol Levels ◽  
The Impact

Gestational diabetes mellitus (GDM) associates with fetal endothelial dysfunction (ED), which occurs independently of adequate glycemic control. Scarce information exists about the impact of different GDM therapeutic schemes on maternal dyslipidemia and obesity and their contribution to the development of fetal-ED. The aim of this study was to evaluate the effect of GDM-treatments on lipid levels in nonobese (N) and obese (O) pregnant women and the effect of maternal cholesterol levels in GDM-associated ED in the umbilical vein (UV). O-GDM women treated with diet showed decreased total cholesterol (TC) and low-density lipoproteins (LDL) levels with respect to N-GDM ones. Moreover, O-GDM women treated with diet in addition to insulin showed higher TC and LDL levels than N-GDM women. The maximum relaxation to calcitonin gene-related peptide of the UV rings was lower in the N-GDM group compared to the N one, and increased maternal levels of TC were associated with even lower dilation in the N-GDM group. We conclude that GDM-treatments modulate the TC and LDL levels depending on maternal weight. Additionally, increased TC levels worsen the GDM-associated ED of UV rings. This study suggests that it could be relevant to consider a specific GDM-treatment according to weight in order to prevent fetal-ED, as well as to consider the possible effects of maternal lipids during pregnancy.

The effect of some brain/gut peptides on plasma cholesterol levels in the rat

Peptides ◽  
1980 ◽  
Vol 1 (4) ◽  
pp. 381-382 ◽  
Author(s):  
Ludvik Peric-Golia ◽  
Clark F. Gardner ◽  
Milena Peric-Golia
Keyword(s):  
Plasma Cholesterol ◽  
Gut Peptides ◽  
Cholesterol Levels
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