Communication and the Primate Brain: Insights from Neuroimaging Studies in Humans, Chimpanzees and Macaques

AbstractLarge-scale comparative neuroscience requires data from many species and, ideally, at multiple levels of description. Here, we contribute to this endeavor by presenting diffusion and structural MRI data from eight primate species that have not or rarely been described in the literature. The selected samples from the Primate Brain Bank cover a prosimian, New and Old World monkeys, and a great ape. We present preliminary labelling of the cortical sulci and tractography of the optic radiation, dorsal part of the cingulum bundle, and dorsal parietal–frontal and ventral temporal-frontal longitudinal white matter tracts. Both dorsal and ventral association fiber systems could be observed in all samples, with the dorsal tracts occupying much less relative volume in the prosimian than in other species. We discuss the results in the context of known primate specializations and present hypotheses for further research. All data and results presented here are available online as a resource for the scientific community.

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Effect of clinically relevant doses of vortioxetine and citalopram on serotonergic PET markers in the nonhuman primate brain

Neuropsychopharmacology ◽

10.1038/s41386-019-0442-4 ◽

2019 ◽

Vol 44 (10) ◽

pp. 1706-1713 ◽

Cited By ~ 1

Author(s):

Kai-Chun Yang ◽

Vladimir Stepanov ◽

Nahid Amini ◽

Stefan Martinsson ◽

Akihiro Takano ◽

...

Keyword(s):

Nonhuman Primate ◽

Primate Brain

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Experimental delayed radiation necrosis of the brain

Journal of Neurosurgery ◽

10.3171/jns.1979.51.5.0587 ◽

1979 ◽

Vol 51 (5) ◽

pp. 587-596 ◽

Cited By ~ 18

Author(s):

Albert N. Martins ◽

Ralph E. Severance ◽

James M. Henry ◽

Thomas F. Doyle

Keyword(s):

Rhesus Monkeys ◽

Radiation Necrosis ◽

Clinical Signs ◽

Control Group ◽

Content Type ◽

Brain Irradiation ◽

Primate Brain ◽

High Doses ◽

The Brain ◽

Male Rhesus

✓ The authors have designed an experiment to detect a hitherto unrecognized interaction between high doses of the glucocorticoid, dexamethasone, and brain irradiation. Eighteen juvenile male rhesus monkeys received 1800 rads to the whole brain in 8.5 minutes. For 1½ days before and 10½ days after the irradiation, nine animals received approximately 2.9 mg/kg/day of dexamethasone intramuscularly in addition to irradiation, while the remaining nine animals served as the control group and received saline. All animals eventually developed a progressive neurological syndrome, and died of delayed radiation necrosis of the brain. The two groups were compared with regard to latency to onset of clinical signs, survival time, and number, distribution, and location of lesions of radionecrosis. Large doses of dexamethasone did not alter the susceptibility of the primate brain to delayed radiation necrosis. Detailed morphological study of the radionecrotic lesions supports the hypothesis that most, if not all, of the lesions develop as the consequence of injury to blood vessels.

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