Re: Postoperative Frontal Central Necrosis

1999 ◽  
Vol 9 (5) ◽  
pp. 158.3-158
Author(s):  
Daniel E. Rousso
Keyword(s):  
Central Necrosis

Multiple Aseptic Pulmonary Nodules With Central Necrosis in Association With Pyoderma Gangrenosum

CHEST Journal ◽  
2001 ◽  
Vol 119 (3) ◽  
pp. 977-978 ◽  
Author(s):  
Stefan Krüger ◽  
Christian Breuer ◽  
Ernst R. Schwarz ◽  
Werner Piroth ◽  
Baffour Amo-Takyi
Keyword(s):  
Pyoderma Gangrenosum ◽  
Pulmonary Nodules ◽  
Central Necrosis

FORAMINAL NERVE SHEATH TUMORS

Neurosurgery ◽  
2009 ◽  
Vol 64 (suppl_2) ◽  
pp. A33-A43 ◽  
Author(s):  
Judith A. Murovic ◽  
Iris C. Gibbs ◽  
Steven D. Chang ◽  
Bret C. Mobley ◽  
Jon Park ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Medical Center ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Central Necrosis ◽  
Nerve Sheath Tumors ◽  
Peripheral Nerve Sheath Tumors ◽  
Neurological Findings ◽  
Nerve Sheath ◽  
Asymptomatic Case

Abstract OBJECTIVE To conduct a retrospective review of outcomes in 15 patients with 18 foraminal tumors, including 17 benign peripheral nerve sheath tumors and 1 malignant peripheral nerve sheath tumor, who underwent CyberKnife (Accuray, Inc., Sunnyvale, CA) radiosurgery at Stanford University Medical Center from 1999 to 2006. METHODS Symptoms and findings, neurofibromatosis (NF) association, previous radiation, imaging, dosimetry, tumor volume, central necrosis, and the relation of these factors to outcomes were evaluated. RESULTS Before treatment, 1 asymptomatic patient had radiculopathic findings, 3 patients experienced local pain with intact neurological examinations, and 7 patients had radiculopathic complaints with intact (1 patient), radiculopathic (4 patients), or radiculomyelopathic examinations (2 patients). Five patients had myelopathic complaints and findings. Three patients had NF1-associated neurofibromas, 1 patient with NF2 had a schwannoma, and 1 patient had a schwannomatosis-related lesion. Two likely radiation-induced lesions, a neurofibroma and a malignant peripheral nerve sheath tumor, were observed. Prescribed doses ranging from 16 to 24 Gy, delivered in 1 to 3 fractions of 6 to 20 Gy, resulted in maximum tumor doses ranging from 20.9 to 30 Gy. Target volumes ranged from 1.36 to 16.9 mL. After radiosurgery, the asymptomatic case remained asymptomatic, and neurological findings improved. Thirteen of 15 symptomatic patients with (12 patients) or without (3 patients) neurological findings improved (3 cases after resection) or remained stable, and 2 patients worsened. Symptoms and examinations remained stable or improved in 8 (80%) of 10 patients with schwannomas and 3 (60%) of 5 patients with neurofibromas. Tumor volumes decreased in 12 (67%) of 18 tumors and increased in 3 tumors. Tumor volumes decreased in 8 of 10 schwannomas and 3 of 7 neurofibromas. Central necrosis developed in 8 (44%) of 18 tumors. CONCLUSION CyberKnife radiosurgery resulted in pain relief and functional preservation in selected foraminal peripheral nerve sheath tumors and a malignant peripheral nerve sheath tumor. Symptomatic and neurological improvements were more noticeable with schwannomas. Myelopathic symptoms may necessitate surgical debulking before radiosurgery.

Lobular neoplasia displaying central necrosis: A potential diagnostic pitfall

2010 ◽  
Vol 206 (8) ◽  
pp. 544-549 ◽  
Author(s):  
Marilin Rosa ◽  
Amir Mohammadi ◽  
Shahla Masood
Keyword(s):  
Lobular Neoplasia ◽  
Central Necrosis ◽  
Diagnostic Pitfall

scholarly journals Sclerosing angiomatoid nodular transformation of the spleen

2019 ◽  
Vol 12 (9) ◽  
pp. e229757
Author(s):  
Jiaying Liao ◽  
Aya Musbahi ◽  
Kaushik Dasgupta ◽  
Herwig Thibaut ◽  
Bussa Gopinath
Keyword(s):  
Weight Loss ◽  
Laparoscopic Splenectomy ◽  
Abdominal Ultrasound ◽  
Laboratory Analysis ◽  
High Likelihood ◽  
Unintentional Weight Loss ◽  
Histopathological Findings ◽  
Central Necrosis ◽  
Sclerosing Angiomatoid Nodular Transformation ◽  
Splenic Mass

The authors described a case of sclerosing angiomatoid nodular transformation of the spleen (SANT) in a 50-year-old woman presented with persistent neutrophilia and unintentional weight loss. An incidental splenic mass was initially found on abdominal ultrasound. It was found to be progressive in size and with high likelihood of central necrosis on further CT of abdomen and pelvis. The patient subsequently underwent an uneventful laparoscopic splenectomy. The splenic specimens were sent for laboratory analysis and the histopathological findings were highly suggestive of SANT. The patient then had routine surgical follow-ups and was eventually discharged with no further clinical concern.

scholarly journals Clinical and Pathological Characteristics of Autoimmune Hepatitis with Acute Presentation

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Yi Shen ◽  
Changli Lu ◽  
Ruoting Men ◽  
Jianping Liu ◽  
Tinghong Ye ◽  
...  
Keyword(s):  
Autoimmune Hepatitis ◽  
Disease Onset ◽  
Histological Evaluation ◽  
Central Necrosis ◽  
Acute Presentation ◽  
Significant Difference ◽  
Long Term Follow Up ◽  
Lobular Inflammation

Aim. To study the differences between acute presentation-autoimmune hepatitis (A-AIH) and chronic autoimmune hepatitis (C-AIH). Methods. Through long-term follow-up, 80 patients were included in our study by using the revised international autoimmune hepatitis group (IAIHG) score and were divided into acute and chronic groups for comparison. Results. No significant difference was found in the gender, age, IAIHG score (pretreatment/posttreatment), definite diagnosis rate, extrahepatic autoimmune disease, onset time, or treatment before biopsy between the acute and chronic groups. In terms of clinical symptoms, A-AIH patients were more prone to jaundice, anorexia, yellow urine, and detesting oil than C-AIH patients, but melena only occurred in chronic group (P<0.05). The acute group exhibited more severe injury upon histological evaluation, with lobular inflammation and bile duct injury, especially central necrosis of the lobule, more pronounced in this group (P<0.05). Conclusion. A-AIH had manifestations of acute hepatitis and presented cholestasis. Serum indicators could preliminarily distinguish A-AIH and C-AIH. Histologically, the primary manifestation of A-AIH was lobular inflammation, which was usually accompanied by lobular central necrosis. For the diagnosis of A-AIH, more attention should be paid to long-term follow-up. This study was registered at ClinicalTrials.gov (identifier: NCT02994537).

scholarly journals Three Cases of Fibrous Meningioma with Prominent Central Necrosis

2007 ◽  
Vol 16 (2) ◽  
pp. 135-140
Author(s):  
Nozomu Murai ◽  
Takaaki Kaneko
Keyword(s):  
Central Necrosis
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