scholarly journals Rare causes of respiratory insufficiency in newborns

2020 ◽  
pp. S637-S647
Author(s):  
J Brucknerová ◽  
J Babala ◽  
E Ujházy ◽  
M Mach ◽  
I Juránek ◽  
...  
Keyword(s):  
Respiratory Insufficiency ◽  
Final Diagnosis ◽  
Postnatal Period ◽  
Acute Respiratory Insufficiency ◽  
Asymptomatic Patients ◽  
Multidisciplinary Cooperation ◽  
Term Newborns ◽  
Prenatal Intervention ◽  
Rare Group ◽  
Spontaneous Delivery

Congenital lung masses (CLM) the rare group of causes of acute respiratory insufficiency (RI) in newborns include congenital airway pulmonary malformation (CAPM), congenital overinflation, bronchopulmonary sequestration, and bronchial atresia. The presenting group consists of 13 newborns who were admitted to the Neonatal Department of Intensive Medicine (NDIM) during January 1st 2015-December 31st 2019 (8 males, 5 females, 2 premature/11 term newborns, spontaneous delivery: 2, caesarean section: 11) with positive prenatal diagnosis of CAPM in all cases. In 2 cases prenatal intervention was performed (drainage of the amniotic fluid, attempt of thoracentesis). Signs of acute RI immediately after delivery were seen in 5 newborns. Postnatal echocardiographic investigation confirmed the presence of increased pulmonary pressure in 8 patients, no patient had congenital heart abnormality. A thorax x-ray was positive also in asymptomatic patients. Computed tomography in patients brought detailed information about the position, size and character of CAPM. Six patients underwent surgery. In 15.4 % right lungs were affected by cystic malformation and in 23 % left lungs were affected. A final diagnosis of CAPM was confirmed in 5 patients using histopathologic examination. Multidisciplinary cooperation during prenatal as well as postnatal period is necessary.

Aggressive Treatment of Acute Respiratory Insufficiency*

1976 ◽  
Vol 69 (6) ◽  
pp. 749-751 ◽  
Author(s):  
JOSEPH M. CIVETTA ◽  
REMIGIO J. FLOR ◽  
LEONARD O. SMITH
Keyword(s):  
Respiratory Insufficiency ◽  
Aggressive Treatment ◽  
Acute Respiratory Insufficiency

scholarly journals Serum Procalcitonin Concentrations in Term Delivering Mothers and Their Healthy Offspring: A Longitudinal Study

2000 ◽  
Vol 46 (10) ◽  
pp. 1583-1587 ◽  
Author(s):  
Marcello Assumma ◽  
Fabrizio Signore ◽  
Lucia Pacifico ◽  
Naila Rossi ◽  
John F Osborn ◽  
...  
Keyword(s):  
Risk Factors ◽  
Longitudinal Study ◽  
Group B Streptococcus ◽  
Neonatal Infection ◽  
Postnatal Period ◽  
Perinatal Factors ◽  
Healthy Neonate ◽  
Term Newborns ◽  
Group B ◽  
Endogenous Synthesis

Abstract Background: The reported sensitivities and specificities of procalcitonin (PCT) concentrations for the diagnosis of neonatal infection vary widely. A postnatal increase of PCT has been observed in healthy term newborns with a peak at ≈24 h of age, and many questions remain regarding maternal and perinatal factors that may influence the normal PCT kinetics during the immediate postnatal period. Methods: We prospectively investigated the association between the serum PCT values obtained from 121 mothers at delivery and serum PCT in their healthy, term offspring at birth as well as at 24 and 48 h of age. We also analyzed whether obstetric and perinatal factors would alter maternal and neonatal PCT response. Results: PCT concentrations in the babies at birth were significantly higher than in the mothers (P <0.0001), with even larger differences at 24 and 48 h of age. None of the variables identified from maternal and perinatal histories had a significant effect on maternal PCT response. In the healthy neonate, the variables that significantly affected the concentration of PCT at birth were the mothers’ PCT (P <0.01), maternal group B streptococcus colonization (P <0.05), and rupture of membranes ≥18 h (P <0.01). The coefficient of linear correlation between the mother’s PCT concentration and that of the baby at birth was 0.32 (P <0.01). The only variable that significantly altered the PCT concentration at both 24 (P <0.01) and 48 (P <0.01) h of age was rupture of membranes ≥18 h. Nonetheless, the PCT response observed during the 48-h period after birth among healthy babies born to mothers with risk factors for infection was well below that reported previously among age-matched neonates with sepsis. Conclusions: The postnatal increase of PCT observed in the healthy neonate with peak values at 24 h of age most likely represents endogenous synthesis. In estimating the sensitivities and specificities of PCT for diagnosis of sepsis throughout the initial 48 h of life, it is important to consider the normal PCT kinetics and the pattern(s) of PCT response in the healthy neonate.

Spontaneous Biliothorax (Thoracobilia) Following Cholecystopleural Fistula Presenting as an Acute Respiratory Insufficiency

CHEST Journal ◽  
1994 ◽  
Vol 106 (3) ◽  
pp. 961-963 ◽  
Author(s):  
Fabiola Delcò ◽  
Guido Domenighetti ◽  
Drazen Kauzlaric ◽  
Diego Donati ◽  
Giorgio Mombelli
Keyword(s):  
Respiratory Insufficiency ◽  
Acute Respiratory Insufficiency

scholarly journals A negative iodine balance is found in healthy neonates compared with neonates with thyroid agenesis

1999 ◽  
Vol 161 (1) ◽  
pp. 115-120 ◽  
Author(s):  
B Bakker ◽  
T Vulsma ◽  
J de Randamie ◽  
AM Achterhuis ◽  
B Wiedijk ◽  
...  
Keyword(s):  
Urinary Iodine ◽  
Postnatal Period ◽  
Urinary Iodine Excretion ◽  
Term Neonates ◽  
Significant Difference ◽  
Iodine Metabolism ◽  
Iodine Excretion ◽  
Term Newborns ◽  
Hypothyroid Patients ◽  
Tsh Stimulation

We studied the effects of the presence or absence of the thyroid gland on the iodine metabolism and excretion in term Dutch newborns by performing a retrospective study of the urinary iodine excretion in 193 term newborns with abnormal congenital hypothyroidism screening results. Thirty-six euthyroid newborns with decreased thyroxine-binding globulin levels were compared with 157 hypothyroid patients, 54 due to thyroid agenesis and 103 due to thyroid dysgenesis. A significant difference in the urinary iodine excretion was observed between the agenesis group (mean: 28 micrograms/24 h) and the euthyroid newborns (mean: 46 micrograms/24 h, P=0.001). In conclusion, healthy, euthyroid, term newborns excreted more iodine in their urine than newborns with thyroid agenesis. These results strongly indicated the existence of a temporarily negative iodine balance: the excretion of iodine prevailed over the intake and the newborn's thyroidal iodine, stored during pregnancy, could be used for thyroxine synthesis in the postnatal period. Since healthy term neonates were able to maintain adequate plasma free thyroxine concentrations under normal TSH stimulation, the prenatally acquired iodine stores could be considered sufficiently high to compensate for the transient postnatal losses.

The contents of neurospecific enolase and neurotrofic growth factor in the cord blood of healthy full-term newborns elective planned caesarean section surgery and spontaneous delivery

2015 ◽  
Vol 64 (6) ◽  
pp. 38-42
Author(s):  
Antonina Yurievna Morozova ◽  
Yuliya Pavlovna Milyutina ◽  
Aleksandr Vartanovich Arutyunyan ◽  
Inna Ivanovna Evsyukova
Keyword(s):  
Growth Factor ◽  
Caesarean Section ◽  
Blood Serum ◽  
Neuron Specific Enolase ◽  
Full Term ◽  
Umbilical Blood ◽  
Umbilical Blood Serum ◽  
Term Newborns ◽  
Low Levels ◽  
Spontaneous Delivery

The contents of neuron-specific enolase (NSE) and brain-derived neurotrophic factor (BDNF) was studied in the umbilical blood serum of healthy full-term newborns elective planned caesarean section and spontaneous delivery. The study has established that their levels in umbilical blood serum after elective planned caesarean section surgery are lover, than after spontaneous delivery. The authors of the article discuss the causes and possible effects of low levels of BDNF of newborns extrected elective planned caesarean section surgery before 39 weeks.

Recombinant Human Growth Hormone in Chronic and Acute Respiratory Insufficiency

1996 ◽  
Vol 46 (4-5) ◽  
pp. 222-229 ◽  
Author(s):  
Claude Pichard ◽  
Phillipe Jolliet ◽  
Jean-Claude Chevrolet ◽  
Jacques André Romand ◽  
Daniel Slosman
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Respiratory Insufficiency ◽  
Recombinant Human Growth Hormone ◽  
Human Growth ◽  
Acute Respiratory Insufficiency

ACUTE RESPIRATORY INSUFFICIENCY

Nursing ◽  
1977 ◽  
Vol 7 (12) ◽  
pp. 24-31
Author(s):  
HANNELORE SWEETWOOD
Keyword(s):  
Respiratory Insufficiency ◽  
Acute Respiratory Insufficiency
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