scholarly journals Cough Reflex Sensitivity and Fractional Exhaled Nitric Oxide in Children With Asthma

2021 ◽  
pp. S455-S461
Author(s):  
P KUNC ◽  
J FABRY ◽  
T ZATKO ◽  
M GRENDAR ◽  
M TATAR ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Rank Correlation ◽  
Exhaled Nitric Oxide ◽  
Control Group ◽  
Fractional Exhaled Nitric Oxide ◽  
Cough Reflex Sensitivity ◽  
Cough Reflex ◽  
Cough Variant Asthma ◽  
Asthmatic Children ◽  
Children With Asthma

Individual studies have suggested the utility of fractional exhaled nitric oxide (FeNO) measurement in detecting cough-variant asthma and eosinophilic bronchitis in patients with chronic cough. The aim of this study was to clarify a correlation of cough reflex sensitivity and fractional exhaled nitric oxide in asthmatic children. 25 children with asthma and 15 controls were submitted to cough reflex sensitivity measurement – capsaicin aerosol in doubling concentrations (from 0.61 to 1250 µmol/l) was inhaled by a single breath method. Concentrations of capsaicin causing two (C2) and five coughs (C5) were reported. Fractional exhaled nitric oxide (FeNO) measurement was included. Asthmatic children (11 boys and 14 girls, mean age 9±1 years) and control group (unconfirmed diagnosis of asthma) (6 boys and 9 girls, mean age 8±1 years) were included into the study. FeNO vs. C2 in asthma (Spearman´s rank correlation: -0.146, p=0.49); FENO vs. C5 in asthma (Spearman´s rank correlation: -0.777, p=0.71). We found that there is no correlation between cough reflex sensitivity and fractional exhaled nitric oxide either in children with asthma or in the control group.

Relationships between fractional exhaled nitric oxide levels and FEF25%–75% in children with asthma

2016 ◽  
Vol 4 (1) ◽  
pp. 14 ◽  
Author(s):  
Hyunwook Lim ◽  
Eunji Kim ◽  
Chang Hoon Lim ◽  
Sang Hee Park ◽  
Ji Tae Choung ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Exhaled Nitric Oxide ◽  
Fractional Exhaled Nitric Oxide ◽  
Children With Asthma

scholarly journals Values of fractional exhaled nitric oxide for cough-variant asthma in children with chronic cough

2018 ◽  
Vol 10 (12) ◽  
pp. 6616-6623 ◽  
Author(s):  
Jing Zhou ◽  
Xianhong Zhao ◽  
Xu Zhang ◽  
Xingmei Yu ◽  
Yuqing Wang ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Chronic Cough ◽  
Exhaled Nitric Oxide ◽  
Fractional Exhaled Nitric Oxide ◽  
Cough Variant Asthma ◽  
Asthma In Children

Fractional Exhaled Nitric Oxide (FENO), Lung Function and Airway Hyperresponsiveness in Naïve Atopic Asthmatic Children

2004 ◽  
Vol 41 (7) ◽  
pp. 759-765 ◽  
Author(s):  
Michele Miraglia del Giudice ◽  
F. P. Brunese ◽  
G. L. Piacentini ◽  
M. Pedullà ◽  
C. Capristo ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Lung Function ◽  
Airway Hyperresponsiveness ◽  
Exhaled Nitric Oxide ◽  
Fractional Exhaled Nitric Oxide ◽  
Asthmatic Children

The Effect of Obesity on the Level of Fractional Exhaled Nitric Oxide in Children with Asthma

2013 ◽  
Vol 162 (2) ◽  
pp. 156-162 ◽  
Author(s):  
Mustafa Erkoçoglu ◽  
Aysenur Kaya ◽  
Celal Özcan ◽  
Aysegül Akan ◽  
Emine Vezir ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Exhaled Nitric Oxide ◽  
Fractional Exhaled Nitric Oxide ◽  
Children With Asthma

scholarly journals Fractional Exhaled Nitric Oxide Measurement in Pulmonary Hypertension: A Follow-Up Study

2017 ◽  
Vol 24 (3) ◽  
pp. 483-488 ◽  
Author(s):  
Nilay Orak Akbay ◽  
Zuleyha Bingol ◽  
Esen Kiyan ◽  
Ekrem Bilal Karaayvaz ◽  
Ahmet Kaya Bilge ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Pulmonary Hypertension ◽  
Pulmonary Function Tests ◽  
Exhaled Nitric Oxide ◽  
World Health ◽  
Control Group ◽  
Healthy Controls ◽  
Fractional Exhaled Nitric Oxide

Pulmonary hypertension (PH) is a fatal disease although significant improvements in treatment are achieved. Easily implemented and noninvasive prognostic techniques are needed while following-up these patients. The aim was to investigate the role of fractional exhaled nitric oxide (FeNO) in follow-up for patients with PH. In this longitudinal study, patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic PH (CTEPH) who were seen in PH Outpatient Clinic, Istanbul Faculty of Medicine, Istanbul University, were enrolled in the study. Echocardiography, 6-minute walking test, brain natriuretic peptide, and FeNO measurements were performed, and World Health Organization functional class was evaluated to all patients at baseline, and third, and sixth months. Right-heart catheterization and pulmonary function tests at the time of diagnosis were recorded. The study comprised 31 patients (23 women, 8 men; mean age: 53.4 ± 17.1 years) with PAH (n = 19) and CTEPH (n = 12) and 80 healthy controls. Patients with PH had lower FeNO values than the control group (16.5 ppb vs 19.8 ppb; P < .05). Fractional exhaled nitric oxide values did not change during follow-up and did not correlate with other follow-up measures except tricuspid annular plane systolic excursion values. Fractional exhaled nitric oxide was higher in the idiopathic PAH subgroup at baseline and at third month than patients with PAH associated with other diseases. Fractional exhaled nitric oxide did not change in patients who had clinical deterioration. As a conclusion; Patients with PH had lower FeNO values than healthy controls, but FeNO did not change significantly during follow-up. Large-scale studies with prolonged follow-up periods are needed to understand the role of FeNO in the follow-up of the patients with PH.

scholarly journals Fractional exhaled nitric oxide and respiratory complaints in Hajj pilgrims wearing a cotton towel or plain cotton ihram

2019 ◽  
Vol 48 (4) ◽  
pp. 030006051989100
Author(s):  
Sultan Ayoub Meo ◽  
Muhammad Iqbal ◽  
Abeer Al-Masri ◽  
Inam Zia ◽  
Sibtain Afzal
Keyword(s):  
Nitric Oxide ◽  
Sore Throat ◽  
Respiratory Symptoms ◽  
Clinical History ◽  
Respiratory Illness ◽  
Exhaled Nitric Oxide ◽  
Control Group ◽  
Fractional Exhaled Nitric Oxide ◽  
Respiratory Illnesses ◽  
Runny Nose

Objective Hajj is an important component of Islam. This study aimed to determine the effect of wearing a cotton towel or plain cotton ihram on the onset of respiratory symptoms and fractional exhaled nitric oxide (FeNO) levels in Hajj pilgrims. Methods One hundred male nonsmoking subjects (age: 20–60 years) without a previous clinical history of respiratory illnesses were included. Fifty subjects were dressed in a cotton towel ihram and 50 wore a plain cotton ihram (control group). Respiratory symptoms and FeNO levels were recorded on the day before leaving for Hajj, when ihrams were removed, and when the pilgrims had returned home. Results Pilgrims who wore cotton towel ihrams showed significantly higher rates of respiratory symptoms, including being generally ill, coughing, a sore throat, and a runny nose, than those who wore plain ihrams. FeNO levels also tended to be higher in pilgrims who wore a cotton towel ihram compared with those with a plain cotton ihram during and after Hajj. Conclusions Hajj pilgrims who wear cotton towel ihrams may have a risk of respiratory symptoms, including a cough, sore throat, and runny nose. Therefore, a plain cotton ihram is advisable while performing Hajj to minimize respiratory illness.

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