scholarly journals The Treatment of Orofacial Pain by Using Transcranial Direct Current Stimulation

2019 ◽  
pp. S367-S372
Author(s):  
J. FRICOVÁ ◽  
K. ENGLEROVÁ ◽  
J. NEDVÍDEK ◽  
R. ROKYTA
Keyword(s):  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Orofacial Pain ◽  
Short Form ◽  
Old Patients ◽  
Dental Surgery ◽  
Direct Current Stimulation ◽  
Non Invasive ◽  
Common Diagnosis

Neurostimulation methods are used in the treatment of chronic pain, although mainly for pharmacology resistant pain. Transcranial Direct Current Stimulation (tDCS) is a non-invasive neurostimulation method using low direct current (0.029-0.08 mA/cm2) applied to a cathode and anode, which directly stimulates the cranial surface. The applied current causes the most significant changes directly under the electrodes: the cathode reduces the excitability of cortical neurons, whereas the anode increases excitability. The effect of stimulation usually lasts a few hours up to a few days. We observed 19 patients with chronic orofacial pain. Inclusion criteria for the study were the following: orofacial pain, stable analgesic medication for at least one week before the beginning of stimulation and during its course, and age 18-75 years old. Patients with severe organic brain damage or seizure disease (epilepsy) were not included. The most common diagnosis was secondary trigeminal neuralgia after dental surgery. We measured thermal and tactile stimulation on the face before and after tDCS, then at 14 days. The total follow-up period lasted six months. We evaluated pain on a numerical scale (0-10) at each follow-up. We used sets of inventories focused on the examination of pain (a short form of McGill inventory), depression, anxiety, and pain interference with daily activities. tDCS is a non-invasive stimulation technique that is affordable and can be easily administered, especially when compared to other neurostimulation techniques. Only 15 patients out of the total number of 19 responded to the questionnaires.

Prefrontal Cortex Transcranial Direct Current Stimulation Treatment in Alcohol Dependence Syndrome (PreCoTTA): Study Protocol for a Double-Blind Randomized Sham-Controlled Trial

2021 ◽  
Vol 16 ◽  
Author(s):  
Anagha S. Deshmukh ◽  
Samir Kumar Praharaj ◽  
Shweta Rai ◽  
Asha Kamath ◽  
Dinesh Upadhya
Keyword(s):  
Prefrontal Cortex ◽  
Alcohol Dependence ◽  
Direct Current ◽  
Brain Stimulation ◽  
Transcranial Direct Current Stimulation ◽  
Public Health Problem ◽  
Comprehensive Treatment ◽  
Direct Current Stimulation ◽  
Non Invasive ◽  
Alcohol Dependence Syndrome

Background: Alcohol dependence is a significant public health problem, contributing to the global health burden. Due to its immense socio-economic burden, various psychosocial, psychological, and pharmacological approaches have attempted to alter the behaviour of the patient misusing or abusing alcohol, but their efficacy is modest at best. Therefore, there is a search for newer treatment approaches, including noninvasive brain stimulation in the management of alcohol dependence. We plan to study the efficacy of Prefrontal Cortex Transcranial direct current stimulation Treatment in Alcohol dependence syndrome (PreCoTTA). Methods: Two hundred twenty-five male patients with alcohol dependence syndrome will be randomized into the three study arms (2 active, left dorsolateral prefrontal cortex and left orbitofrontal cortex, and 1 sham) to receive a total of 14 tDCS sessions (10 continuous and 4 booster sessions). Data will be collected from them at five different time points on clinical, neuropsychological and biochemical parameters. In addition, 225 healthy age and education matched controls will be administered the neuropsychological test battery at baseline for comparison with the patient group. Discussion: The proposed study aims to explore the use of non-invasive brain stimulation; tDCS as a treatment alternative. We also aim to overcome the methodological gaps of limited sample sizes, fewer tDCS intervention sessions, lack of long term follow ups to measure the sustainability of gains and lack comprehensive measures to track changes in functioning and abstinence after tDCS intervention. The main outcomes include clinical (reduction in cue-induced craving, time to first drink and QFI); neuropsychological (risk-taking, impulsivity, and other neuropsychological domains) and biochemical markers (BDNF, leptin and adiponectin). The findings of the study will have translational value as it may help to improve the clinician’s ability to effectively manage craving in patients with alcohol dependence syndrome. Furthermore, we will have a better understanding of the neuropsychological and biochemical effects of non-invasive brain stimulation techniques which are of interest in the comprehensive treatment of addiction disorders. Trial registration: The study has been registered with the Clinical Trials Registry-India (CTRI/2020/09/027582) on September 03rd 2020.

Use of transcranial direct current stimulation in poststroke postural imbalance

2021 ◽  
Vol 14 (6) ◽  
pp. e243212
Author(s):  
Tadayasu Tonomura ◽  
Takeshi Satow ◽  
Yuko Hyuga ◽  
Tatsuya Mima
Keyword(s):  
Subarachnoid Haemorrhage ◽  
Treatment Option ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Gait Disturbance ◽  
Direct Current Stimulation ◽  
Non Invasive ◽  
Novel Treatment ◽  
Parietal Area ◽  
Postural Imbalance

Independent gait following stroke is ultimate goal of rehabilitation. Non-invasive neuromodulation achieving it has never been reported. A 74-year-old woman suffered from subarachnoid haemorrhage, followed by hydrocephalus. Both were treated successfully. Even 1 year after the ictus, ambulation was difficult due to truncal instability with lateropulsion mainly to the left side. Transcranial direct current stimulation (tDCS) was applied to the parietal area (2mA for 20 min/day; anode on left side, cathode on right) for 16 days. The intervention improved her truncal instability and she achieved independent gait. tDCS of the parietal area could be a novel treatment option for gait disturbance due to postural instability following stroke.

Sign in / Sign up

Export Citation Format

Share Document