scholarly journals Acute Medication Poisoning Causing Hospital Admissions in Childhood: a 3-Year Prospective Observational Single-Center Study

2019 ◽  
pp. S31-S38 ◽  
Author(s):  
P. MATALOVÁ ◽  
M. PORUBA ◽  
M. WAWRUCH ◽  
P. ONDRA ◽  
K. URBÁNEK
Keyword(s):  
Hospital Admissions ◽  
Accidental Poisoning ◽  
Age Group ◽  
Single Center ◽  
Acute Medication ◽  
Single Center Study ◽  
Wide Range ◽  
Inflammatory Drugs ◽  
Poisoning In Children ◽  
Center Study

Although the risks of medication poisoning in children are often reported, there is a lack of studies addressing this issue. The majority of papers deal with a wide range of xenobiotics poisoning and, in particular, alcohol intoxications. All hospital admissions during three years were prospectively recorded. Patients younger than 19 years of age admitted for acute drug intoxications were further evaluated. A total of 15,069 children were admitted. Of them, 55 were hospitalized for acute medication poisoning. The condition was more common in girls (72.7 % vs. 27.3 %, p<0.01). Toddlers were the largest patient group (36.4 %). Non-steroidal anti-inflammatory drugs (NSAIDs) were the most frequently used agents, with ibuprofen being the leading drug (20 % of all cases). The route of intoxication was almost exclusively oral. Solid drug forms were involved in 40 (72.7 %) cases. There was one fatal accidental poisoning. The highest occurrence of accidental drug intoxications was in the age group from one to three years. Attempted suicides were most frequent among adolescents. We are currently actively dealing with the issue. The cohort has been expanded to include a period of ten years and is being analyzed.

Medium Cut-Off Dialyzer versus Eight Hemodiafiltration Dialyzers: Comparison Using a Global Removal Score

2019 ◽  
Vol 48 (2) ◽  
pp. 167-174 ◽  
Author(s):  
Francisco Maduell ◽  
Lida Rodas ◽  
José Jesús Broseta ◽  
Miquel Gomez ◽  
Marc Xipell ◽  
...  
Keyword(s):  
High Volume ◽  
Treatment Modalities ◽  
High Flux ◽  
Single Center ◽  
Acid Glycoprotein ◽  
Molecular Weights ◽  
Single Center Study ◽  
Wide Range ◽  
Middle Molecules ◽  
Center Study

Background: A novel class of membranes, medium cut-off (MCO) membranes, has recently been designed to achieve interesting removal capacities for middle and large middle molecules in hemodialysis (HD) treatments. The few studies published to date have reported contradictory results regarding middle-sized molecules when comparing MCO dialyzers versus dialyzers used in online hemodiafiltration (OL-HDF). Methods: A prospective, single-center study was carried out in 22 patients. Each patient underwent 9 dialysis sessions with routine dialysis parameters, one with an MCO dialyzer in HD and the other 8 with different dialyzers in OL-HDF. The removal ratio (RR) of urea, creatinine, β2-microglobulin, myoglobin, prolactin, α1-microglobulin, α1-acid glycoprotein, and albumin was intraindividually compared. Albumin loss in dialysate was measured. We propose a global removal score ([ureaRR + β2-microglobulinRR + myoglobinRR + prolactinRR + α1-microglobulinRR + α1-acid glycoproteinRR]/6 – albuminRR) as a new tool for measuring dialyzer effectiveness. Results: No significant differences in the RRs of small and middle molecular range molecules were observed between the MCO vs. OL-HDF dialyzers (range 60–80%). Lower RRs were found for α1-microglobulin and α1-acid glycoprotein without significant differences. The albumin RR was < 11% and dialysate albumin loss was < 3.5 g in all situations without significant differences. The global removal score was 54.9 ± 4.8% with the MCO dialyzer without significant differences. Conclusions: Removal of a wide range of molecular weights, calculated with the proposed global removal score, was almost equal with the MCO dialyzer in HD treatment compared with 8 high-flux dialyzers in high-volume OL-HDF without relevant changes in albumin loss. The global removal score could be a new tool to evaluate the effectiveness of dialyzers and/or different treatment modalities.

scholarly journals Study of clinical profile and management of varicose veins in the department of surgery

2021 ◽  
Vol 8 (8) ◽  
pp. 2399
Author(s):  
Ritvik D. Jaykar ◽  
Sachin C. Jadhav ◽  
Vivek M. Chaudhari
Keyword(s):  
Risk Factors ◽  
Informed Consent ◽  
Selection Criteria ◽  
Varicose Veins ◽  
Lower Limbs ◽  
Age Group ◽  
Single Center ◽  
Younger Age ◽  
Single Center Study ◽  
Center Study

Background: Varicose veins are common problem and are present in at least 10% of the general population. So far as the aetiology is concerned varicose veins mostly occur due to incompetence of their valves. Risk factors for varicose veins include obesity, female sex, inactivity, and family history. Varicose veins do not threaten life and are seldom disabling, but it causes a considerable demand on medical care.Methods: The study was prospective observational single center study. 30 patients were selected for the study which fit in the selection criteria laid down at the beginning of the study. Informed consent was obtained from each patient before any investigations and treatment.Results: The study revealed that the varicose veins of lower limbs are a disease of younger age group, occurring more commonly during third and fifth decades of life. The involvement of long saphenous system was more common.Conclusions: Results of our study are comparable with various other studies in literature. 

scholarly journals Outcomes of Percutaneous Nephrolithotomy in Preschool Age Group: A Single-Center Study

2020 ◽  
Vol 34 (10) ◽  
pp. 1001-1007
Author(s):  
Hakan Bahadir Haberal ◽  
Hasan Serkan Dogan ◽  
Burak Citamak ◽  
Berk Hazir ◽  
Mesut Altan ◽  
...  
Keyword(s):  
Percutaneous Nephrolithotomy ◽  
Preschool Age ◽  
Age Group ◽  
Single Center ◽  
Single Center Study ◽  
Group A ◽  
Center Study

1655: Long-Term Functional Outcome in Orthotopic Bladder Replacement in Women: A Single Center Study

2007 ◽  
Vol 177 (4S) ◽  
pp. 549-549
Author(s):  
Hannes Steiner ◽  
Thomas Akkad ◽  
Christian Gozzi ◽  
Brigitte Springer-Stoehr ◽  
Georg Bartsch
Keyword(s):  
Functional Outcome ◽  
Single Center ◽  
Bladder Replacement ◽  
Single Center Study ◽  
Center Study

ENDOSCOPIC TREATMENT OF RECTAL NEUROENDOCRINE TUMORS IN A 12 YEAR RETROSPECTIVE SINGLE CENTER STUDY

2019 ◽  
Author(s):  
K Dąbkowski ◽  
A Białek ◽  
N Rusiniak-Rossińska ◽  
K Michalska ◽  
B Kos-Kudła ◽  
...  
Keyword(s):  
Neuroendocrine Tumors ◽  
Endoscopic Treatment ◽  
Single Center ◽  
Single Center Study ◽  
Center Study
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