scholarly journals The Development of Selected Cardiovascular Parameters in Patients With Type 2 Diabetes Mellitus During a Spa Treatment

2015 ◽  
pp. S661-S667 ◽  
Author(s):  
E. FIALOVÁ ◽  
O. KITTNAR
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Sympathetic Tone ◽  
Control Group ◽  
Electrical Stability ◽  
Before And After ◽  
Spa Treatment

Diabetes mellitus is not just a simple metabolic disorder, however, it is considered to be a cardiovascular disease of a metabolic origin. This is apparent especially when speaking about type 2 diabetes (DM II). The objective of our study was to determine whether a comprehensive spa treatment (procedures and drinking cure) may affect the level of the sympathetic tone of patients suffering from DM II. As an indicator of the sympathetic tone, selected electrocardiographic parameters derived from the heart rate variability and microwave alternans were chosen. There were 96 patients enrolled in our study: 38 patients with poorly controlled DM II and two control groups: 9 patients with compensated DM II and 49 patients, average age without diabetes or other disorders of the glucose metabolism. All received an identical spa treatment and continued their medical therapy. The electrophysiological examination of patients was performed before and after a three-week spa treatment using the KARDiVAR system. Parameters derived from the analysis of heart rate variability (HRV), microvolt T-wave alternans, and microvolt R-wave alternans were analyzed in order to evaluate the tones of the autonomic nervous system (ANS). The control group showed a slight increase of parameter the index of activity of regulatory systems (IRSA) (4.4±1.3 vs. 3.8±1.4; p=0.006) after the spa treatment, while increased heart rate (80.9±11.0 vs. 74.6±9.6; p=0.028), reduced index of centralization (IC) (1.3±0.6 vs. 2.9±1.4; p=0.027) and reduced index of myocardium (IM) (9.9±7.4 vs. 18.0±6.3; p=0.041) were found in patients with a compensated DM II. Patients with a poorly compensated DM II showed a decreased IM (10.9±8.6 vs. 16.9±5.2; p=0.001) and also a reduced IRSA (4.1±3.5 vs. 6.3±1.9; p=0.001). The results proved favorable changes in ANS cardiovascular control of patients with DM II after a spa treatment, especially in terms of reducing the sympathoadrenal system activity (decreased IRSA), improving electrical stability of the myocardium and increasing centrally controlled heart rate variability without overloading the cardiovascular system (drop of IM).

scholarly journals Heart rate variability is significantly reduced in non-diabetic patients with hypertension

2014 ◽  
Vol 155 (22) ◽  
pp. 865-870 ◽  
Author(s):  
Krisztina Nagy ◽  
Evelin Sipos ◽  
Taha El Hadj Othmane
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Control Group ◽  
Diabetic Patients ◽  
Hypertensive Patients ◽  
Control Subjects ◽  
Co Morbidity

Introductions: Heart rate variability is reduced among patients with hypertension or those with diabetes mellitus. Hypertension and diabetes show frequent co-morbidity, but it is still not entirely clear whether heart arte variability is reduced in non-diabetic patients with hypertension. Aim: The aim of the authors was to evaluate the heart rate variability in hypertensive patients with and without diabetes and in control subjects. Method: 130 patients with hypertension, 48 patients with hypertension and type 2 diabetes mellitus, and 87 control subjects were involved in the study. Minimum, mean and maximum heart rate, and parameters of heart rate variability were measured. Results: The mean of minimum heart rate did not differ significantly between the three groups. However, all other parameters were significantly reduced in patients with hypertension with and without diabetes as compared to the control group. No significant differences were observed between hypertensive patients with and without diabetes mellitus. Conclusions: Heart rate variability is significantly reduced in non-diabetic patients with hypertension. It seems that type 2 diabetes results in no further significant reduction of heart rate variability in patients with hypertension. Orv. Hetil., 2014, 155(22), 865–870.

scholarly journals The influence of type 2 diabetes mellitus on the frequency and complexity of ventricular arrhythmias and heart rate variability in patients after myocardial infarction

2016 ◽  
Vol 73 (11) ◽  
pp. 1050-1055
Author(s):  
Viktor Stoickov ◽  
Marina Deljanin-Ilic ◽  
Dijana Stojanovic ◽  
Stevan Ilic ◽  
Sandra Saric ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Myocardial Infarction ◽  
Type 2 Diabetes ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 2 Diabetes Mellitus ◽  
Ventricular Arrhythmias ◽  
Qt Dispersion ◽  
Rr Intervals

Background/Aim. After myocardial infarction arrhythmic cardiac deaths are significantly more frequent compared to non-arrhythmic ones. The aim of the study was to investigate the influence of type 2 diabetes mellitus (T2DM) on the frequency and complexity of ventricular arrhythmias after myocardial infarction. Methods. The study included 293 patients, mean age 59.5 ? 9.21 years, who were at least six months after acute myocardial infarction with the sinus rhythm, without atrioventricular blocks and branch blocks. In the clinical group 95 (32.42%) patients were with T2DM, while 198 (67.57%) patients were without diabetes. All of the patients were subjected to the following procedures: standard ECG according to which the corrected QT dispersion (QTdc) was calculated, exercise stress test, and 24-hour holter monitoring according to which, the four parameters of time domain of heart rate variability (HRV) were analyzed: standard deviation of all normal RR intervals during 24 hours (SDNN), standard deviation of the averages of normal RR intervals in all five-minute segments during 24 hours (SDANN), the square root of the mean of the sum of the squares of differences between adjacent normal (RMS-SD), and percentage of consequtive RR intervals which differed for more than 50 ms during 24 hours (NN > 50 ms). Results. In patients after myocardial infarction, patients with T2DM had significantly higher percentage of frequent and complex ventricular arrhythmias compared to the patients without diabetes (p < 0.001). The patients with T2DM had significantly higher percentage of residual ischemia (p < 0.001), and arterial hypertension (p < 0.001), compared to patients without diabetes. The patients with T2DM had significantly lower values of HRV parameters: SDNN (p < 0.001); SDANN (p < 0.001); RMS-SD (p < 0.001), and NN > 50 ms (p < 0.001), and significantly higher values of QTdc (p < 0.001) compared to the patients without diabetes. Conclusion. The study showed that type 2 diabetes mellitus has significant influence on ventricular arrhythmias, HRV parameters and QT dispersion in patients after myocardial infarction.

scholarly journals Heart rate variability in type 2 diabetes mellitus: A systematic review and meta-analysis

2018 ◽  
Vol 79 (4) ◽  
pp. 465-466 ◽  
Author(s):  
T. Benichou ◽  
B. Pereira ◽  
M. Mermillod ◽  
P. Daniela ◽  
I. Tauveron ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Type 2 Diabetes ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 2 Diabetes Mellitus ◽  
Meta Analysis
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