scholarly journals Diagnostic Significance of a Mild Decrease of Baroreflex Sensitivity With Respect to Heart Rate in Type 1 Diabetes Mellitus

2013 ◽  
pp. 605-613
Author(s):  
J. SVAČINOVÁ ◽  
N. HONZÍKOVÁ ◽  
A. KRTIČKA ◽  
I. TONHAJZEROVÁ ◽  
K. JAVORKA ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Heart Rate ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Autonomic Dysfunction ◽  
Baroreflex Sensitivity ◽  
Clinical Signs ◽  
Diagnostic Significance

Decreased baroreflex sensitivity is an early sign of autonomic dysfunction in patients with type-1 diabetes mellitus. We evaluated the repeatability of a mild baroreflex sensitivity decrease in diabetics with respect to their heart rate. Finger blood pressure was continuously recorded in 14 young diabetics without clinical signs of autonomic dysfunction and in 14 age-matched controls for 42 min. The recordings were divided into 3-min segments, and the mean inter-beat interval (IBI), baroreflex sensitivity in ms/mm Hg (BRS) and mHz/mm Hg (BRSf) were determined in each segment. These values fluctuated in each subject within 42 min and therefore coefficients of repeatability were calculated for all subjects. Diabetics compared with controls had a decreased mean BRS (p=0.05), a tendency to a shortened IBI (p=0.08), and a decreased BRSf (p=0.17). IBI correlated with BRS in diabetics (p=0.03); this correlation was at p=0.12 in the controls. BRSf was IBI independent (controls: p=0.81, diabetics: p=0.29). We conclude that BRS is partially dependent on mean IBI. Thus, BRS reflects not only an impairment of the quick baroreflex responses of IBI to blood pressure changes, but also a change of the tonic sympathetic and parasympathetic heart rate control. This is of significance during mild changes of BRS. Therefore, an examination of the BRSf index is highly recommended, because this examination improves the diagnostic value of the measurement, particularly in cases of early signs of autonomic dysfunction.

scholarly journals Daily blood pressure variations in patients with type 1 diabetes mellitus and nephropathy

2003 ◽  
Vol 49 (5) ◽  
pp. 5-10
Author(s):  
I. A. Bondar ◽  
V. V. Klimontov ◽  
Ye. A. Korolyova ◽  
L. I. Zheltova
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 1 Diabetes ◽  
Arterial Hypertension ◽  
Type 1 Diabetes Mellitus ◽  
Autonomic Dysfunction ◽  
Blood Pressure Monitoring ◽  
Inpatient Setting ◽  
Systemic Hemodynamic

То study a relationship between systemic hemodynamic parameters, albuminuria, and autonomic dysfunction in patients with type 1 diabetes mellitus (DM-1) without obvious nephropathy, the authors examined 55 patients in the inpatient setting. Twenty-nine patients had a normal urinary albumin excretion (CAE), 26 patients had microalbuminuria. 24-hour blood pressure monitoring (24-h BPM) was occillometrically made. The average daily, average diurnal and nocturnal values of systolic and diastolic blood pressure (BP) were significantly higher in DM-1 patients with microalbuniuria than in those with normal UAE. Routine autonomic cardiovascular tests showed that the incidence and severity of autonomic neuropathy were also higher in patients with microalbuminuria. Arterial hypertension (AH) diagnosed in compliance with the 24-h BPM criteria was detected. in 17.2%) of the DM-1 patients with normal UAE and in 42.3%) of the patients with microalbuminuria. According to the data of 24-h BPM, the incidence of arterial hypertension was 1.7 times as high as that evidenced by single BP measurements. The specific feature of circadian hemodynamic variations in patients with DM-1 was a low nocturnal BP decrease. 37.9%) of the patients with normoalbuminuria and 61.5%) of the patients with microalbuminuria had no normal (>10%)) nocturnal BP lowering. Stepwise regression analysis has ascertained that in patients with DM-1 without obvious nephropathy, systemic hemodynamic disorders are associated with albuminuria, autonomic dysfunction, and glycemic monitoring quality.

scholarly journals Effect of hypoxia on heart rate variability and baroreflex sensitivity during hypoglycemia in type 1 diabetes mellitus

2015 ◽  
Vol 25 (4) ◽  
pp. 243-250 ◽  
Author(s):  
Jacqueline K. Limberg ◽  
Simmi Dube ◽  
Myrthe Kuijpers ◽  
Kathryn E. Farni ◽  
Ananda Basu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Baroreflex Sensitivity

IMPAIRED DIURNAL BLOOD PRESSURE AND HEART RATE VARIATION AND THEIR RELATIONSHIP WITH LEFT-VENTRICULAR FUNCTION IN ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS

PEDIATRICS ◽  
2008 ◽  
Vol 121 (Supplement 2) ◽  
pp. S104.2-S105
Author(s):  
Kyriaki Karavanaki ◽  
George Kazianis ◽  
Emmanouil Tsouvalas ◽  
Ilias Konstantopoulos ◽  
Christina Karayianni
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Heart Rate ◽  
Type 1 Diabetes ◽  
Left Ventricular Function ◽  
Type 1 Diabetes Mellitus ◽  
Left Ventricular ◽  
Rate Variation ◽  
Heart Rate Variation

Heart rate variability and circadian variations in type 1 diabetes mellitus

2006 ◽  
Vol 7 (1) ◽  
pp. 45-50 ◽  
Author(s):  
Firat Kardelen ◽  
Gayaz Akcurin ◽  
Halil Ertug ◽  
Sema Akcurin ◽  
Iffet Bircan
Keyword(s):  
Diabetes Mellitus ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Circadian Variations

Early blood pressure alterations are associated with pro-inflammatory markers in type 1 diabetes mellitus

2016 ◽  
Vol 31 (2) ◽  
pp. 151-156 ◽  
Author(s):  
I Mateo-Gavira ◽  
F J Vílchez-López ◽  
M V García-Palacios ◽  
F Carral-San Laureano ◽  
F M Visiedo-García ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Inflammatory Markers
Sign in / Sign up

Export Citation Format

Share Document