scholarly journals KIR gene complexity in primates

10.33540/866 ◽  
2021 ◽  
Author(s):  
◽  
Jesse Bruijnesteijn
Keyword(s):  
Kir Gene

scholarly journals Cost-effective and fast KIR gene-content genotyping by multiplex melting curve analysis

HLA ◽  
2018 ◽  
Vol 92 (6) ◽  
pp. 384-391
Author(s):  
Leonardo M. Amorim ◽  
Tiago H. S. Santos ◽  
Jill A. Hollenbach ◽  
Paul J. Norman ◽  
Wesley M. Marin ◽  
...  
Keyword(s):  
Melting Curve ◽  
Cost Effective ◽  
Curve Analysis ◽  
Gene Content ◽  
Melting Curve Analysis ◽  
Kir Gene

Study of the KIR gene profiles and analysis of the phylogenetic relationships of Rajbanshi population of West Bengal, India

2013 ◽  
Vol 74 (5) ◽  
pp. 673-680 ◽  
Author(s):  
Pokhraj Guha ◽  
Soumen Bhattacharjee ◽  
Chittaranjan Nayak ◽  
Tapas Kumar Chaudhuri
Keyword(s):  
Phylogenetic Relationships ◽  
West Bengal ◽  
Gene Profiles ◽  
Kir Gene

scholarly journals Analysis of KIR3DP1 Polymorphism Provides Relevant Information on Centromeric KIR Gene Content

2018 ◽  
Vol 201 (5) ◽  
pp. 1460-1467 ◽  
Author(s):  
Maria Bono ◽  
Daniela Pende ◽  
Alice Bertaina ◽  
Alessandro Moretta ◽  
Mariella Della Chiesa ◽  
...  
Keyword(s):  
Relevant Information ◽  
Gene Content ◽  
Kir Gene

scholarly journals Characterisation of B killer cell immunoglobulin-like receptor genes and telomeric and centromeric motifs in hematopoietic stem cell transplantation donors in Vojvodina, Serbia

Genetika ◽  
2017 ◽  
Vol 49 (1) ◽  
pp. 345-354
Author(s):  
Dusica Ademovic-Sazdanic ◽  
Svetlana Vojvodic ◽  
S. Popovic ◽  
N. Konstantinidis
Keyword(s):  
Relapse Prevention ◽  
Hematological Malignancies ◽  
Killer Cell ◽  
Simple Algorithm ◽  
Hematopoietic Stem ◽  
Graft Versus Host ◽  
Kir Genes ◽  
Graft Versus Leukemia ◽  
Kir Gene ◽  
Kir Genotypes

The outcome of HSCT is strongly in?uenced by the genetic similarity or identity in the HLA genes that affects the incidence of graft-versus-host disease (GvHD). Successful allogeneic HSCT, however, depends also on T-cell mediated graft-versus-leukemia (GvL) effect, in which donor-derived T cells and natural killer (NK) cells kill these malignant cells in the patient, therefore playing a crucial role in relapse prevention. The aim of this study was to make the predictive analysis of the structure and distribution of B KIR alleles and centromeric and telomeric KIR genotypes in HSCT donors in Vojvodina with regard to their contribution to protection from relapse. A total of 124 first-degree relatives of patients with hematological malignancies were examined for the presence or absence of 15 KIR genes by using of PCR-SSO technique with Luminex xMap technology. The percentage of individuals carrying each KIR gene, centromeric and telomeric KIR haplotypes and genotypes was determined by direct counting. Sixty two percent of the HSCT donors in Vojvodina carry A KIR haplotype, while nearly 38% carry B KIR haplotype. The distribution of B KIR genes showed that among 124 studied HSCT donors, 31(25%) do not carry none of the KIR genes belonging to B group, 71.77% of donors have two or more B KIR genes, 61.29% of them carry KIR 2DL2 and 2DS2 or more B KIR genes. The analysis of centromeric and telomeric KIR genotypes, showed that Cen-A1/Tel-A1 genotype had a highest frequency of 51.47% and Cen-B2/Tel-B1 the lowest frequency of 1.30%. The usage of donor KIR B gene content and centromeric and telomeric KIR gene structure could be used in development of a simple algorithm to identify donors who will provide the most protection against the relapse in related HSC transplants.

Study of KIR gene expression at the mRNA level in specific donor-derived NK cells after allogeneic HSCT

2020 ◽  
Vol 72 (3) ◽  
pp. 135-141 ◽  
Author(s):  
Ying Li ◽  
Tian Wang ◽  
Xing Hu ◽  
Huanhuan Zhang ◽  
Luyao Chen ◽  
...  
Keyword(s):  
Gene Expression ◽  
Nk Cells ◽  
Mrna Level ◽  
Allogeneic Hsct ◽  
Kir Gene

Clinical and histopatholowgical changes in different KIR gene profiles in chronic HCV Romanian patients

2020 ◽  
Author(s):  
Larisa Denisa Ursu ◽  
Bogdan Calenic ◽  
Mircea Diculescu ◽  
Alina Dima ◽  
Iulia Teodora Stoian ◽  
...  
Keyword(s):  
Gene Profiles ◽  
Chronic Hcv ◽  
Kir Gene

14-OR: KIR gene polymorphism detected with a multiplex PCR-SSP method

2007 ◽  
Vol 68 (1) ◽  
pp. S15
Author(s):  
J.Y. Sun ◽  
A. Oki ◽  
L. Gaidulis ◽  
D. Senitzer
Keyword(s):  
Gene Polymorphism ◽  
Multiplex Pcr ◽  
Kir Gene

Identification of a single killer immunoglobulin-like receptor (KIR) gene in the porcine leukocyte receptor complex on chromosome 6q

2006 ◽  
Vol 58 (5-6) ◽  
pp. 481-486 ◽  
Author(s):  
Jennifer G. Sambrook ◽  
Harminder Sehra ◽  
Penny Coggill ◽  
Sean Humphray ◽  
Sophie Palmer ◽  
...  
Keyword(s):  
Receptor Complex ◽  
Leukocyte Receptor Complex ◽  
Kir Gene
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