Negative indirect effects of hurricanes on recruitment of range-expanding mangroves

2020 ◽  
Vol 644 ◽  
pp. 65-74
Author(s):  
RS Smith ◽  
JA Blaze ◽  
JE Byers
Keyword(s):  
Salt Marshes ◽  
Large Scale ◽  
Return Time ◽  
Avicennia Germinans ◽  
Invasion Success ◽  
Bare Sediment ◽  
Invading Species ◽  
Hurricane Season ◽  
Before And After ◽  
Positive Direct

Disturbances often have positive, direct effects on invasions by dispersing propagules or creating environmental conditions that favor invasive species. However, disturbances that alter interactions between resident and invading species could also affect invasion success. In northeast Florida, the black mangrove Avicennia germinans is expanding into salt marshes, where it interacts with the dead litter (wrack) of the native marsh cordgrass Spartina alterniflora. From 2015-2017, we performed monthly surveys before and after 2 hurricanes in 3 marsh microhabitats (bare sediment, vegetation, wrack) to quantify mangrove propagule and seedling densities. Wrack increased propagule retention up to 10 times relative to other microhabitats. Hurricanes did not directly harm mangrove propagules or seedlings. However, storm surge relocated wrack to upland environments, which indirectly inhibited mangroves by temporarily disrupting the facilitative effects of wrack on propagule recruitment and exposing intertidal bare patches that decreased propagule retention and seedling establishment. Wrack remained absent from intertidal areas for 1-3 mo. Because hurricane season overlaps with propagule recruitment, hurricane timing and wrack return time to intertidal areas influence the degree that hurricanes disrupt wrack-mangrove interactions. We demonstrate that large-scale disturbances can negatively and indirectly affect invader recruitment by altering interactions with resident species.

The Effect of Active Site-inhibited Factor VIIa on Tissue Factor-initiated Coagulation Using Platelets before and after Aspirin Administration

1997 ◽  
Vol 78 (04) ◽  
pp. 1202-1208 ◽  
Author(s):  
Marianne Kjalke ◽  
Julie A Oliver ◽  
Dougald M Monroe ◽  
Maureane Hoffman ◽  
Mirella Ezban ◽  
...  
Keyword(s):  
Tissue Factor ◽  
Active Site ◽  
Large Scale ◽  
Thrombin Generation ◽  
Factor Viia ◽  
Dependent Manner ◽  
Antithrombotic Agent ◽  
Before And After ◽  
Ic50 Values

SummaryActive site-inactivated factor VIIa has potential as an antithrombotic agent. The effects of D-Phe-L-Phe-L-Arg-chloromethyl ketone-treated factor VIla (FFR-FVIIa) were evaluated in a cell-based system mimicking in vivo initiation of coagulation. FFR-FVIIa inhibited platelet activation (as measured by expression of P-selectin) and subsequent large-scale thrombin generation in a dose-dependent manner with IC50 values of 1.4 ± 0.8 nM (n = 8) and 0.9 ± 0.7 nM (n = 7), respectively. Kd for factor VIIa binding to monocytes ki for FFR-FVIIa competing with factor VIIa were similar (11.4 ± 0.8 pM and 10.6 ± 1.1 pM, respectively), showing that FFR-FVIIa binds to tissue factor in the tenase complex with the same affinity as factor VIIa. Using platelets from volunteers before and after ingestion of aspirin (1.3 g), there were no significant differences in the IC50 values of FFR-FVIIa [after aspirin ingestion, the IC50 values were 1.7 ± 0.9 nM (n = 8) for P-selectin expression, p = 0.37, and 1.4 ± 1.3 nM (n = 7) for thrombin generation, p = 0.38]. This shows that aspirin treatment of platelets does not influence the inhibition of tissue factor-initiated coagulation by FFR-FVIIa, probably because thrombin activation of platelets is not entirely dependent upon expression of thromboxane A2.

Towards Control of an Estuary

1987 ◽  
Vol 19 (9) ◽  
pp. 155-174
Author(s):  
Henk L. F. Saeijs
Keyword(s):  
Shallow Water ◽  
Storm Surge ◽  
Salt Marshes ◽  
Large Scale ◽  
Western Europe ◽  
Oxygen Depletion ◽  
Negative Effects ◽  
Intertidal Flats ◽  
Environmental Consequences ◽  
Short Time

The Delta Project is in its final stage. In 1974 it was subjected to political reconsideration, but it is scheduled now for completion in 1987. The final touches are being put to the storm-surge barrier and two compartment dams that divide the Oosterschelde into three areas: one tidal, one with reduced tide, and one a freshwater lake. Compartmentalization will result in 13% of channels, 45% of intertidal flats and 59% of salt marshes being lost. There is a net gain of 7% of shallow-water areas. Human interventions with large scale impacts are not new in the Oosterschelde but the large scale and short time in which these interventions are taking place are, as is the creation of a controlled tidal system. This article focusses on the area with reduced tide and compares resent day and expected characteristics. In this reduced tidal part salt marshes will extend by 30–70%; intertidal flats will erode to a lower level and at their edges, and the area of shallow water will increase by 47%. Biomass production on the intertidal flats will decrease, with consequences for crustaceans, fishes and birds. The maximum number of waders counted on one day and the number of ‘bird-days' will decrease drastically, with negative effects for the wader populations of western Europe. The net area with a hard substratum in the reduced tidal part has more than doubled. Channels will become shallower. Detritus import will not change significantly. Stratification and oxygen depletion will be rare and local. The operation of the storm-surge barrier and the closure strategy chosen are very important for the ecosystem. Two optional closure strategies can be followed without any additional environmental consequences. It was essential to determine a clearly defined plan of action for the whole area, and to make land-use choices from the outset. How this was done is briefly described.

scholarly journals THU0642-HPR EVOLUTION OF THE PERCEPTIONS OF RA PATIENTS AFTER EDUCATION PATIENT SESSION TEACHING METHOTREXATE SELF-INJECTION A PROSPECTIVE PILOT STUDY

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 566.1-566
Author(s):  
S. Afilal ◽  
H. Rkain ◽  
B. Berchane ◽  
J. Moulay Berkchi ◽  
S. Fellous ◽  
...  
Keyword(s):  
Pilot Study ◽  
Patient Education ◽  
Median Duration ◽  
Large Scale ◽  
Education Session ◽  
Prospective Pilot Study ◽  
Mean Delay ◽  
Lack Of Information ◽  
Level Of Satisfaction ◽  
Before And After

Background:Methotrexate is a gold standard for treatment of RA. In our context, RA patients prefer to be injected by paramedics rather than self-injecting. This can be explained by patients’ bad perceptions of self-injection or lack of information. Appropriate self-injection education can therefore be an important element in overcoming these obstacles and improving disease self-management.Objectives:Compare the RA patients’ perceptions on methotrexate self-injection before and after a patient education session.Methods:Prospective pilot study that included 27 consecutive patients (81.5% female, mean age 44.4 years, illiteracy rate 40.7%) with RA (median duration of progression of 4 years, mean delay in referral for specialist of 6 months, median duration of methotrexate use of 1 year). The patients benefited from an individual patient education session to learn how to self-inject with methotrexate subcutaneously. The patient education session was supervised by a nurse and a rheumatologist with a control a week later. Perceptions of the reluctance to self-inject and the difficulties encountered by patients were assessed before the patient education session, after the 1st and 2nd self-injection of methotrexate using a 10 mm visual analog scale. Patients also reported their level of satisfaction (10 mm VAS) after the 1st and 2nd self-injection.Results:The mean duration of patient education session is 13 min.Table I compares the evolution of the degrees of reluctance to self-injection, the difficulties encountered, and the satisfaction experienced by the patients.Table 1.Evolution of RA patients’ perceptions on the methotrexate self-injection. (N = 27)BeforeAfter the 1stself-injectionAfter the 2end self-injectionpVAS reluctance (0-10mm)6,5 ± 3,62,2 ± 2,91,0 ± 2,3<0,0001VAS difficulty (0-10mm)7,5 ± 2,62,5 ± 2,71,0 ± 1,9<0,0001VAS satisfaction (0-10mm)-8,9 ± 1,89,5 ± 1,50,002Conclusion:This study suggests the effectiveness of a methotrexate self-injection patient education session in RA patients. It also highlights the value of patient education in rheumatologic care. A large-scale study is necessary to better interpret and complete these preliminary results from this pilot study.Disclosure of Interests:None declared

scholarly journals Dynamic variations in salinity and potassium grade of a potassium-rich brine deposit in Lop Nor basin, China

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lichun Ma ◽  
Kai Wang ◽  
Yu Zhang ◽  
Qingfeng Tang ◽  
Hui Yan
Keyword(s):  
Large Scale ◽  
Sustainable Use ◽  
Potassium Sulfate ◽  
Middle Pleistocene ◽  
Underground Brine ◽  
Average Decrease ◽  
Rational Development ◽  
Mining History ◽  
Before And After ◽  
Lop Nor

AbstractThe Quaternary Lop Nor playa is the largest production base of potassium sulfate in the world. It has a mining history of more than 10 years, and its share in the Chinese potassium sulfate market is about 50% to-date. In this basin, the high-salinity potassium-rich brines are mainly contained in Middle Pleistocene–Holocene glauberite strata. Based on the monitoring of the underground brine table and geochemical analysis, this study reveals variations in the underground brine table and potassium-bearing grade before and after large-scale mining in the Lop Nor potash deposit. The results showed that the underground brine table and potassium sulfate grade decreased by varying degrees over sub-mineral areas after large-scale mining. The underground brine table declined by 8.5 m, on average, in the Luobei depression, by 6.4 m in the Tenglong platform and by 1.9 m in the Xinqing platform. However, the potassium-bearing grade showed the different trend. The Tenglong platform had the largest decline with average decreases in layers W1, W2 and W3 of 18.2%, 13.0% and 24.8%, respectively. In the Xinqing platform, the average decrease in layersW2 and W3 were 17.4% and 16.0% respectively. The Luobei depression decreases were relatively small (W1, W2 and W3 decreased 4.3%, 4.2% and 3.1%, respectively). This research provides a theoretical basis for the rational development and sustainable use of the potassium-rich brines in the Lop Nor basin.

scholarly journals Species and characteristics of volatile organic compounds emitted from an auto-repair painting workshop

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
M. Y. Song ◽  
H. Chun
Keyword(s):  
Volatile Organic Compounds ◽  
Organic Compounds ◽  
Large Scale ◽  
Butyl Acetate ◽  
Small Scale ◽  
Indoor Environments ◽  
Voc Emissions ◽  
Volatile Organic ◽  
Before And After ◽  
Adsorption Systems

AbstractVolatile organic compounds (VOCs) are secondary pollutant precursors having adverse impacts on the environment and human health. Although VOC emissions, their sources, and impacts have been investigated, the focus has been on large-scale industrial sources or indoor environments; studies on relatively small-scale enterprises (e.g., auto-repair workshops) are lacking. Here, we performed field VOC measurements for an auto-repair painting facility in Korea and analyzed the characteristics of VOCs emitted from the main painting workshop (top coat). The total VOC concentration was 5069–8058 ppb, and 24–35 species were detected. The VOCs were mainly identified as butyl acetate, toluene, ethylbenzene, and xylene compounds. VOC characteristics differed depending on the paint type. Butyl acetate had the highest concentration in both water- and oil-based paints; however, its concentration and proportion were higher in the former (3256 ppb, 65.5%) than in the latter (2449 ppb, 31.1%). Comparing VOC concentration before and after passing through adsorption systems, concentrations of most VOCs were lower at the outlets than the inlets of the adsorption systems, but were found to be high at the outlets in some workshops. These results provide a theoretical basis for developing effective VOC control systems and managing VOC emissions from auto-repair painting workshops.

scholarly journals Correcting for experiment-specific variability in expression compendia can remove underlying signals

GigaScience ◽  
2020 ◽  
Vol 9 (11) ◽  
Author(s):  
Alexandra J Lee ◽  
YoSon Park ◽  
Georgia Doing ◽  
Deborah A Hogan ◽  
Casey S Greene
Keyword(s):  
Gene Expression ◽  
Large Scale ◽  
Original Signal ◽  
Batch Effects ◽  
Technical Variability ◽  
The Past ◽  
Statistical Correction ◽  
Before And After ◽  
Data Collections ◽  
Biological Patterns

Abstract Motivation In the past two decades, scientists in different laboratories have assayed gene expression from millions of samples. These experiments can be combined into compendia and analyzed collectively to extract novel biological patterns. Technical variability, or "batch effects," may result from combining samples collected and processed at different times and in different settings. Such variability may distort our ability to extract true underlying biological patterns. As more integrative analysis methods arise and data collections get bigger, we must determine how technical variability affects our ability to detect desired patterns when many experiments are combined. Objective We sought to determine the extent to which an underlying signal was masked by technical variability by simulating compendia comprising data aggregated across multiple experiments. Method We developed a generative multi-layer neural network to simulate compendia of gene expression experiments from large-scale microbial and human datasets. We compared simulated compendia before and after introducing varying numbers of sources of undesired variability. Results The signal from a baseline compendium was obscured when the number of added sources of variability was small. Applying statistical correction methods rescued the underlying signal in these cases. However, as the number of sources of variability increased, it became easier to detect the original signal even without correction. In fact, statistical correction reduced our power to detect the underlying signal. Conclusion When combining a modest number of experiments, it is best to correct for experiment-specific noise. However, when many experiments are combined, statistical correction reduces our ability to extract underlying patterns.

scholarly journals Preparedness and Response Activities of the VA Home-Based Primary Care Program Around the Fall 2017 Hurricane Season

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 591-591
Author(s):  
Tamar Wyte-Lake ◽  
Claudia Der-Martirosian ◽  
Aram Dobalian
Keyword(s):  
Primary Care ◽  
Large Scale ◽  
Care Program ◽  
Department Of Veterans Affairs ◽  
Home Based Primary Care ◽  
Home Based ◽  
Early Implementation ◽  
Hurricane Season ◽  
Patient Health ◽  
At Risk Populations

Abstract Individuals aged seventy-five or older, who often present with multiple comorbidities and decreased functional status, typically prefer to age in their homes. Additionally, as in-home medical equipment evolves, more medically vulnerable individuals can receive care at home. Concomitantly, large-scale natural disasters disproportionally affect both the medically complex and the older old, two patient groups responsible for most medical surge after a disaster. To understand how to ameliorate this surge, we examined the activities of the nine US Department of Veterans Affairs Home-Based Primary Care programs during the 2017 Atlantic Hurricane Season. These and similar programs under Medicare connect the homebound to the healthcare community. Study findings support early implementation of preparedness procedures and intense post-Hurricane patient tracking as a means of limiting reductions in care and preventing significant disruptions to patient health. Engaging with home-based primary care programs during disasters is central to bolstering community resilience for these at-risk populations.

Large-Scale Sport Events and Resident Well-Being: Examining PERMA and the Gold Coast 2018 Commonwealth Games

2021 ◽  
pp. 1-14
Author(s):  
Jason Doyle ◽  
Kevin Filo ◽  
Alana Thomson ◽  
Thilo Kunkel
Keyword(s):  
Large Scale ◽  
Positive Emotions ◽  
Well Being ◽  
Host Community ◽  
Social Psychological ◽  
Community Members ◽  
Community Based ◽  
Before And After ◽  
Sport Events ◽  
Commonwealth Games

Delivering community-based benefits is oftentimes cited to justify the high costs associated with hosting large-scale events. The current research is embedded in positive psychology to examine how an event impacts host community members’ PERMA domains, reflected through positive emotions, engagement, relationships, meaning, and accomplishment. Adopting a longitudinal approach, the authors interviewed 15 host community members before and after a large-scale sport event to determine if and how the event impacted their well-being. The findings uncovered evidence that the event activated positive emotions, relationships, and meaning across both phases, and evidence of accomplishment within the postevent phase. The findings contribute to the knowledge by examining the links between large-scale sport events and well-being throughout the event lifecycle. This research forwards implications for event bidding committees, event organizers, and host community officials to maximize community well-being through hosting large-scale events and to help justify associated expenses from a social–psychological perspective.

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