Resilience to ocean acidification: decreased carbonic anhydrase activity in sea anemones under high pCO2 conditions

2016 ◽  
Vol 559 ◽  
pp. 257-263 ◽  
Author(s):  
P Ventura ◽  
MD Jarrold ◽  
PL Merle ◽  
S Barnay-Verdier ◽  
T Zamoum ◽  
...  
Keyword(s):  
Carbonic Anhydrase ◽  
Ocean Acidification ◽  
Carbonic Anhydrase Activity ◽  
High Pco2 ◽  
Sea Anemones

scholarly journals Independent effects of seawater pH and high PCO2 on olfactory sensitivity in fish: possible role of carbonic anhydrase

2021 ◽  
pp. jeb.238485
Author(s):  
Zélia Velez ◽  
Rita A. Costa ◽  
Wenjing Wang ◽  
Peter C. Hubbard
Keyword(s):  
Carbonic Anhydrase ◽  
Glutamic Acid ◽  
Ocean Acidification ◽  
Olfactory Receptor ◽  
High Pco2 ◽  
Gilthead Seabream ◽  
Olfactory Sensitivity ◽  
Seawater Ph ◽  
Olfactory Receptor Neurones

Ocean acidification may alter olfactory-driven behaviour in fish by direct effects on the peripheral olfactory system; olfactory sensitivity is reduced in CO2-acidified seawater. The current study tested whether this is due to elevated PCO2 or the consequent reduction in seawater pH and, if the former, investigate the possible involvement of carbonic anhydrase, the enzyme responsible for the hydration of CO2 and production of carbonic acid. Olfactory sensitivity to amino acids was assessed by extracellular multi-unit recording from the olfactory nerve of the gilthead seabream (Sparus auratus L,) in normal seawater (pH ∼8.2), and after acute exposure to acidified seawater (pH ∼7.7, but normal PCO2; ∼340 µatm) and high PCO2 seawater (∼1400 µatm) at normal pH (∼8.2). Reduced pH in the absence of elevated PCO2 caused reduction in olfactory sensitivity to L-serine, L-leucine, L-arginine and L-glutamine, but not L-glutamic acid. Increased PCO2 in the absence of changes in pH caused reduced olfactory sensitivity to L-serine, L-leucine and L-arginine, including increases in their thresholds of detection, but had no effect on sensitivity to L-glutamine and L-glutamic acid. Inclusion of 1 mM acetazolamide (a membrane-permeant inhibitor of carbonic anhydrase) in the seawater reversed the inhibition of olfactory sensitivity to L-serine caused by high PCO2. Ocean acidification may reduce olfactory sensitivity by reduction in seawater pH and intracellular pH (of olfactory receptor neurones); the former by reducing odorant-receptor affinity, and the latter by reducing the efficiency of olfactory transduction. The physiological role of carbonic anhydrase in the olfactory receptor neurones remains to be explored.

1123: Renal Oxalate Transport Depends on Local Carbonic Anhydrase Activity in the Proximal Tubule

2004 ◽  
Vol 171 (4S) ◽  
pp. 296-296
Author(s):  
Michael Straub ◽  
Joséphine Befolo-Elo ◽  
Richard E Hautmann ◽  
Edgar Braendle
Keyword(s):  
Carbonic Anhydrase ◽  
Proximal Tubule ◽  
Carbonic Anhydrase Activity ◽  
Oxalate Transport

RENAL CARBONIC ANHYDRASE IN PREMATURE AND MATURE INFANTS

PEDIATRICS ◽  
1951 ◽  
Vol 7 (2) ◽  
pp. 182-185
Author(s):  
RICHARD DAY ◽  
JANE FRANKLIN
Keyword(s):  
Carbonic Anhydrase ◽  
Premature Infants ◽  
Carbonic Anhydrase Activity ◽  
Renal Carbonic Anhydrase

The carbonic anhydrase activity in the kidneys of premature infants was studied because it was thought that if the renal enzyme is as deficient as that in the blood, inefficiency in acidification of urine might result. In contrast with the blood, postmortem specimens of kidneys of premature infants were found to exhibit carbonic anhydrase activity similar to that found in the case of kidneys from older infants and adults.

The Effect of Cholera Toxin on Choroid Plexus Carbonic Anhydrase Activity In Vitro

1980 ◽  
Vol 1 (4) ◽  
pp. 333-339
Author(s):  
Arthur M. Feldman ◽  
Mel H. Epstein ◽  
Fallon Maylack ◽  
Saul W. Brusilow
Keyword(s):  
Carbonic Anhydrase ◽  
Choroid Plexus ◽  
Cholera Toxin ◽  
Carbonic Anhydrase Activity
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