scholarly journals Molecular diagnostics, field validation, and phylogenetic analysis of Quahog Parasite Unknown (QPX), a pathogen of the hard clam Mercenaria mercenaria

2002 ◽  
Vol 52 ◽  
pp. 233-247 ◽  
Author(s):  
NA Stokes ◽  
LM Ragone Calvo ◽  
KS Reece ◽  
EM Burreson
Keyword(s):  
Phylogenetic Analysis ◽  
Molecular Diagnostics ◽  
Mercenaria Mercenaria ◽  
Hard Clam ◽  
Field Validation ◽  
Quahog Parasite Unknown

Effects of temperature on hard clam (Mercenaria mercenaria) immunity and QPX (Quahog Parasite Unknown) disease development: I. Dynamics of QPX disease

2011 ◽  
Vol 106 (2) ◽  
pp. 314-321 ◽  
Author(s):  
Soren F. Dahl ◽  
Mickael Perrigault ◽  
Qianqian Liu ◽  
Jackie L. Collier ◽  
Debra A. Barnes ◽  
...  
Keyword(s):  
Mercenaria Mercenaria ◽  
Hard Clam ◽  
Disease Development ◽  
Effects Of Temperature ◽  
Quahog Parasite Unknown

Cytotoxicity of quahog parasite unknown (QPX) toward hard clam (Mercenaria mercenaria) haemocytes and interactions between different pathogen isolates and host strains

Parasitology ◽  
2009 ◽  
Vol 136 (11) ◽  
pp. 1281-1289 ◽  
Author(s):  
MICKAEL PERRIGAULT ◽  
BASSEM ALLAM
Keyword(s):  
Mercenaria Mercenaria ◽  
Neutral Red ◽  
Hard Clam ◽  
Field Investigations ◽  
Uptake Assay ◽  
Successful Establishment ◽  
Quahog Parasite Unknown ◽  
Transmission Studies

SUMMARYThe ability of pathogens to neutralize host defence mechanisms represents a fundamental requisite in the successful establishment of an infection. Host-pathogen interactions between quahog parasite unknown (QPX) and its hard clam host are poorly understood. Our prior in vivo investigations have shown that different QPX isolates display varying levels of pathogenicity toward clams. Similarly, field investigations and laboratory transmission studies revealed some variations in the susceptibility of different hard clam stocks to QPX infection. An in vitro approach was developed in this study to evaluate the toxicity of QPX cells and extracellular products toward haemocytes using a neutral red uptake assay. Results demonstrated that QPX produces virulence factors that are cytotoxic to M. mercenaria haemocytes. This cytotoxicity appears to be induced by clam factors, suggesting that it may play an important role in supporting QPX infection and proliferation within the host. Moreover, application of this technique to different QPX isolates and clam broodstocks indicates variations of QPX cytotoxicity in agreement with previous in vivo experiments, strengthening the existence of different QPX strains.

Effects of temperature on hard clam (Mercenaria mercenaria) immunity and QPX (Quahog Parasite Unknown) disease development: II. Defense parameters

2011 ◽  
Vol 106 (2) ◽  
pp. 322-332 ◽  
Author(s):  
Mickael Perrigault ◽  
Soren F. Dahl ◽  
Emmanuelle Pales Espinosa ◽  
Laura Gambino ◽  
Bassem Allam
Keyword(s):  
Mercenaria Mercenaria ◽  
Hard Clam ◽  
Disease Development ◽  
Effects Of Temperature ◽  
Quahog Parasite Unknown

scholarly journals Identification of variants associated with hard clam, Mercenaria mercenaria, resistance to Quahog Parasite Unknown disease

Genomics ◽  
2020 ◽  
Vol 112 (6) ◽  
pp. 4887-4896
Author(s):  
Sarah Farhat ◽  
Arnaud Tanguy ◽  
Emmanuelle Pales Espinosa ◽  
Ximing Guo ◽  
Isabelle Boutet ◽  
...  
Keyword(s):  
Mercenaria Mercenaria ◽  
Hard Clam ◽  
Quahog Parasite Unknown

scholarly journals Complete mitochondrial genome of the hard clam (Mercenaria mercenaria)

2019 ◽  
Vol 4 (2) ◽  
pp. 3738-3739
Author(s):  
Zhi Hu ◽  
Hao Song ◽  
Cong Zhou ◽  
Zheng-Lin Yu ◽  
Mei-Jie Yang ◽  
...  
Keyword(s):  
Mitochondrial Genome ◽  
Complete Mitochondrial Genome ◽  
Mercenaria Mercenaria ◽  
Hard Clam

Modulatory effects of hard clam (Mercenaria mercenaria) tissue extracts on the in vitro growth of its pathogen QPX

2009 ◽  
Vol 100 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Mickael Perrigault ◽  
Deenie M. Buggé ◽  
Chen Chuan Hao ◽  
Bassem Allam
Keyword(s):  
Mercenaria Mercenaria ◽  
Hard Clam ◽  
In Vitro Growth ◽  
Tissue Extracts
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