Early host–pathogen interactions in a marine bivalve: Crassostrea virginica pallial mucus modulates Perkinsus marinus growth and virulence

2013 ◽  
Vol 104 (3) ◽  
pp. 237-247 ◽  
Author(s):  
E Pales Espinosa ◽  
S Winnicki ◽  
B Allam
Keyword(s):  
Crassostrea Virginica ◽  
Marine Bivalve ◽  
Perkinsus Marinus ◽  
Host Pathogen Interactions ◽  
Host Pathogen

Spatiotemporal Structure of Host-Pathogen Interactions in a Metapopulation

2009 ◽  
Vol 174 (3) ◽  
pp. 308
Author(s):  
Soubeyrand ◽  
Laine ◽  
Hanski ◽  
Penttinen
Keyword(s):  
Host Pathogen Interactions ◽  
Spatiotemporal Structure ◽  
Host Pathogen

scholarly journals Porcine small intestinal organoids as a model to explore ETEC–host interactions in the gut

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Bjarne Vermeire ◽  
Liara M. Gonzalez ◽  
Robert J. J. Jansens ◽  
Eric Cox ◽  
Bert Devriendt
Keyword(s):  
Intestinal Epithelial ◽  
Gut Health ◽  
Functional Responses ◽  
Host Pathogen Interactions ◽  
Epithelial Surface ◽  
Host Interactions ◽  
Intestinal Organoids ◽  
Host Pathogen ◽  
Small Intestinal

AbstractSmall intestinal organoids, or enteroids, represent a valuable model to study host–pathogen interactions at the intestinal epithelial surface. Much research has been done on murine and human enteroids, however only a handful studies evaluated the development of enteroids in other species. Porcine enteroid cultures have been described, but little is known about their functional responses to specific pathogens or their associated virulence factors. Here, we report that porcine enteroids respond in a similar manner as in vivo gut tissues to enterotoxins derived from enterotoxigenic Escherichia coli, an enteric pathogen causing postweaning diarrhoea in piglets. Upon enterotoxin stimulation, these enteroids not only display a dysregulated electrolyte and water balance as shown by their swelling, but also secrete inflammation markers. Porcine enteroids grown as a 2D-monolayer supported the adhesion of an F4+ ETEC strain. Hence, these enteroids closely mimic in vivo intestinal epithelial responses to gut pathogens and are a promising model to study host–pathogen interactions in the pig gut. Insights obtained with this model might accelerate the design of veterinary therapeutics aimed at improving gut health.

scholarly journals Movement can mediate temporal mismatches between resource availability and biological events in host–pathogen interactions

2021 ◽  
Author(s):  
Tobias Kürschner ◽  
Cédric Scherer ◽  
Viktoriia Radchuk ◽  
Niels Blaum ◽  
Stephanie Kramer‐Schadt
Keyword(s):  
Resource Availability ◽  
Host Pathogen Interactions ◽  
Host Pathogen

Convergent evolution and mimicry of protein linear motifs in host–pathogen interactions

2015 ◽  
Vol 32 ◽  
pp. 91-101 ◽  
Author(s):  
Lucía Beatriz Chemes ◽  
Gonzalo de Prat-Gay ◽  
Ignacio Enrique Sánchez
Keyword(s):  
Convergent Evolution ◽  
Host Pathogen Interactions ◽  
Host Pathogen ◽  
Linear Motifs

scholarly journals Host-Pathogen Interactions

1983 ◽  
Vol 72 (2) ◽  
pp. 557-563 ◽  
Author(s):  
Lawrence I. Weinstein ◽  
Peter Albersheim
Keyword(s):  
Host Pathogen Interactions ◽  
Host Pathogen
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