scholarly journals Genetic basis of differences in myxospore count between whirling disease-resistant and -susceptible strains of rainbow trout

2012 ◽  
Vol 102 (2) ◽  
pp. 97-106 ◽  
Author(s):  
ER Fetherman ◽  
DL Winkelman ◽  
GJ Schisler ◽  
MF Antolin
2012 ◽  
Vol 24 (2) ◽  
pp. 110-120 ◽  
Author(s):  
Eric J. Wagner ◽  
Matt Bartley ◽  
Ronney Arndt ◽  
Randall W. Oplinger ◽  
M. Douglas Routledge

2018 ◽  
Vol 30 (4) ◽  
pp. 280-290 ◽  
Author(s):  
Brian W. Avila ◽  
Dana L. Winkelman ◽  
Eric R. Fetherman

2016 ◽  
Vol 78 (4) ◽  
pp. 366-373 ◽  
Author(s):  
Eric R. Fetherman ◽  
Jonathan A. Wardell ◽  
Chris J. Praamsma ◽  
Marta K. Hura

2018 ◽  
Author(s):  
Devon E. Pearse ◽  
Nicola J. Barson ◽  
Torfinn Nome ◽  
Guangtu Gao ◽  
Matthew A. Campbell ◽  
...  

AbstractTraits with different fitness optima in males and females cause sexual conflict when they have a shared genetic basis. Heteromorphic sex chromosomes can resolve this conflict and protect sexually antagonistic polymorphisms but accumulate deleterious mutations. However, many taxa lack differentiated sex chromosomes, and how sexual conflict is resolved in these species is largely unknown. Here we present a chromosome-anchored genome assembly for rainbow trout (Oncorhynchus mykiss) and characterize a 56 Mb double-inversion supergene that mediates sex-specific migration through sex-dependent dominance, a mechanism that reduces sexual conflict. The double-inversion contains key photosensory, circadian rhythm, adiposity, and sexual differentiation genes and displays frequency clines associated with latitude and temperature, revealing environmental dependence. Our results constitute the first example of sex-dependent dominance across a large autosomal supergene, a novel mechanism for sexual conflict resolution capable of protecting polygenic sexually antagonistic variation while avoiding the homozygous lethality and deleterious mutation load of heteromorphic sex chromosomes.


<em>Abstract.</em>—Laboratory challenges of two rainbow trout <em>Oncorhynchus mykiss </em>strains with <em>Myxobolus cerebralis </em>triactinomyxons confirm the resistance to whirling disease of the Hofer trout strain. Although the number of fish that became infected and developed clinical disease was similar for the Hofer and the Trout Lodge strains at all challenge doses, the median spore numbers were lower at all challenge doses for the Hofer rainbow trout. Parasite challenge doses required to produce lesions of high severity were 10-fold lower for the Trout Lodge strain (100 triactinomyxons) than the Hofer strain (1,000 triactinomyxons). Challenges of the Hofer strain with other common salmonid pathogens; the myxozoans <em>Ceratomyxa shasta </em>and <em>Tetracapsuloides bryosalmonae</em>, the bacterium <em>Yersinia ruckeri</em>, and the viruses Salmonid herpes-like virus type 1 and infectious hematopoietic necrosis virus demonstrate that the susceptibility of the Hofer strain was similar to what would be expected for other strains of rainbow trout, either domestic or wild. These pathogen challenges provide evidence that the Hofer trout present a low risk for introducing any pathogen that might be detrimental to native or established fish populations or further amplifying those that are endemic.


2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Mona Saleh ◽  
Ruth Montero ◽  
Gokhlesh Kumar ◽  
Arun Sudhagar ◽  
Adina Friedl ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document