scholarly journals N-Acetylglucosaminyltransferase V Expression is Implicated in Malignant Phenotype of Human Tongue Squamous Cell Carcinoma.

2005 ◽  
Vol 10 (4) ◽  
pp. 121-129
Author(s):  
Makiko Kyan ◽  
Yuichiro Onodera ◽  
Tadashi Iizuka ◽  
Ken-ichi Notani ◽  
Takao Kohgo ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tongue Squamous Cell Carcinoma ◽  
Malignant Phenotype ◽  
Human Tongue

miR-222 targets VGLL4 to promote growth of tongue squamous cell carcinoma

2020 ◽  
Vol 10 (1) ◽  
pp. 102-111
Author(s):  
Liang Shi ◽  
Xiaobin Song ◽  
Ketao Wang ◽  
Shaohua Liu ◽  
Yong Wang
Keyword(s):  
Squamous Cell Carcinoma ◽  
Protein Expression ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tumor Model ◽  
Tongue Squamous Cell Carcinoma ◽  
Migration And Invasion ◽  
Oral Keratinocytes ◽  
Human Tongue

We investigated whether regulation of VGLL4 by miR-222 affects proliferation, migration, invasion, and apoptosis in human tongue squamous cell carcinoma (TSCC) cells. Nanometer Magnetic beads were prepared to extract RNA in CAL27/human oral keratinocytes (HOK). Correlation between expression of miR-222 and VGLL4 in CAL27/human oral keratinocytes (HOK) was analyzed using RT-PCR and western blot. The cellular effects of miR-222/VGLL4 interactions were detected by cck8, transwell, and cell scratch assays, and flow cytometry after miR-222 was silenced or overexpressed in CAL27 cells. We assessed tumor growth in vivo, in a subcutaneous tumor model in mice, and assessed VGLL4 protein expression in tumors by immunohistochemistry. We found that miR-222 expression is higher in CAL27 cells than that in HOK cells. VGLL4 was highly expressed in HOK cells relative to CAL27 cells. When miR-222 was overexpressed, VGLL4 mRNA expression was reduced in CAL27 cells, and protein expression was reduced in the in vivo tumor model. Thus, miR-222 may down-regulate VGLL4 to promote proliferation, migration, and invasion of TSCC cells.

MicroRNA-24 induces cisplatin resistance by targeting PTEN in human tongue squamous cell carcinoma

Oral Oncology ◽  
2015 ◽  
Vol 51 (11) ◽  
pp. 998-1003 ◽  
Author(s):  
Xiangqian Zheng ◽  
Jiansen Li ◽  
Chen Peng ◽  
Jingzhu Zhao ◽  
Jiadong Chi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cisplatin Resistance ◽  
Tongue Squamous Cell Carcinoma ◽  
Human Tongue

scholarly journals Expression and Significance of IL-6 and bFGF in Human Tongue Squamous Cell Carcinoma

2017 ◽  
Vol 08 (02) ◽  
pp. 210-215
Author(s):  
Ju-Hua Hou ◽  
Zheng-Bing He ◽  
Xiao-Ju Hou ◽  
Yuan-Yue Liu ◽  
Wen-Jiang Zhang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tongue Squamous Cell Carcinoma ◽  
Human Tongue
Sign in / Sign up

Export Citation Format

Share Document