scholarly journals Comparison of Skin Prick Test Results between Crude Allergen Extracts from Foods and Commercial Allergen Extracts in Atopic Dermatitis by Double-Blind Placebo- Controlled Food Challenge for Milk, Egg, and Soybean

2002 ◽  
Vol 43 (5) ◽  
pp. 613 ◽  
Author(s):  
Tae Eun Kim ◽  
Seok Won Park ◽  
Geun Woong Noh ◽  
Sang Sun Lee
Keyword(s):  
Atopic Dermatitis ◽  
Skin Prick Test ◽  
Food Challenge ◽  
Test Results ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Prick Test ◽  
Allergen Extracts

scholarly journals Safety of barley starch syrup in patients with allergy to cereals

2008 ◽  
Vol 101 (2) ◽  
pp. 165-168
Author(s):  
Merja Nermes ◽  
Henna Karvonen ◽  
Essi Sarkkinen ◽  
Erika Isolauri
Keyword(s):  
Atopic Dermatitis ◽  
Food Processing ◽  
Food Challenge ◽  
Allergic Reactions ◽  
Double Blind ◽  
Food Ingredients ◽  
Double Blind Placebo ◽  
Allergic Symptoms ◽  
Skin Prick Tests

It is not known whether trace amounts of proteins that may remain in cereal-starch-derived food ingredients even after food processing can trigger allergic symptoms in cereal-allergic individuals. The aim of this study was to find out if barley starch syrup causes allergic reactions in patients with allergy to wheat, barley, rye or oats. Fifteen children with allergy to these cereals, confirmed by double-blind placebo-controlled food challenge (DBPCFC), were selected for the study. When exposed to cereals, seven of the children (47 %) showed immediate type reactions, such as urticaria, rash or anaphylaxis. Eight of the children (53 %) showed delayed type reactions, such as deterioration of atopic dermatitis or diarrhoea. The fifteen children with allergy to cereals were exposed to barley starch syrup in DBPCFC and none of them showed any objective signs of allergy. On skin-prick tests (SPT), five of the children (33·3 %) showed a positive ( ≥ 3 mm) reaction to at least one of the cereals but none of them to barley starch syrup. This study confirmed with 98 % confidence that at least 90 % of the patients with verified allergy to cereals will not react with allergic symptoms to barley starch syrup.

scholarly journals The Effect of Birch Pollen Immunotherapy on Apple and rMal d 1 Challenges in Adults with Apple Allergy

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 519 ◽  
Author(s):  
Johanna van der Valk ◽  
Birgit Nagl ◽  
Roy Gerth van Wljk ◽  
Barbara Bohle ◽  
Nicolette de Jong
Keyword(s):  
Skin Prick Test ◽  
Challenge Test ◽  
Birch Pollen ◽  
Food Challenge ◽  
Specific Ige ◽  
P Value ◽  
Double Blind ◽  
P Values ◽  
Prick Test ◽  
Bet V 1

Background: A proportion of patients allergic to birch pollen are also allergic to pit fruit. The objective of this study was to investigate the effect of immunotherapy with birch pollen on birch-pollen-related apple allergy. Method: Patients with birch pollen immunotherapy underwent a skin-prick test with birch pollen, apple and rMal d 1, global assessments and nasal challenges with birch pollen, open food challenge with apple and a double-blind, placebo-controlled test with rMal d 1 at the start of and during the immunotherapy. Measurements of specific IgE in response to Bet v 1 and rMal d 1 and IgG4 in response to Bet v 1 and rMal d 1 took place. Results: Six of eight patients demonstrated an improvement of nasal challenge test results and all patients improved on global assessment during the immunotherapy. The median oral dose of apple required to elicit a reaction increased but was not statistically significant. The patients showed a decrease in skin-prick test values in response to birch pollen (1.05 to 0.36), apple (0.78 to 0.25) and rMal d 1 (0.51 to 0.10) with p-values of 0.04, 0.03 and 0.06, respectively and a decrease of specific IgE in response to Bet v 1 (10.66 kU/L to 5.19 kU/L) and rMal d 1 (0.99 to 0.61 kU/L) with p-values of 0.01 and 0.05, respectively. Only the median specific IgG4 value to Bet v 1 increased from 0.05 to 1.85 mg/L (p-value of 0.02) and not to IgG4 rMal d 1 (0.07 to 0.08 kU/L). Conclusion: The beneficial effects of immunotherapy for birch pollen were accompanied by a limited effect on apple allergy.

Negative Atopy Patch Test and Negative Skin Prick Test Reduce the Need for Oral Food Challenge in Children with Atopic Dermatitis

2011 ◽  
Vol 24 (2) ◽  
pp. 107-112 ◽  
Author(s):  
Angela Peron ◽  
Rossana Tenconi ◽  
Maddalena Leone ◽  
Patrizia Macellaro ◽  
Elena Ceriani ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Skin Prick Test ◽  
Patch Test ◽  
Food Challenge ◽  
Oral Food Challenge ◽  
Atopy Patch Test ◽  
Prick Test ◽  
Negative Skin Prick Test

scholarly journals Evaluation of Cow’s Milk Allergy in a Large Group of Adolescent and Adult Patients with Atopic Dermatitis

2012 ◽  
Vol 55 (3) ◽  
pp. 125-129 ◽  
Author(s):  
Jarmila Čelakovská ◽  
Květuše Ettlerová ◽  
Karel Ettler ◽  
Jaroslava Vaněčková ◽  
Josef Bukač
Keyword(s):  
Atopic Dermatitis ◽  
Food Challenge ◽  
Adult Patients ◽  
Cow’S Milk Allergy ◽  
Cow’S Milk ◽  
Milk Allergy ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Cow's Milk ◽  
Cow's Milk Allergy

Few studies concerning the occurrence of cow’s milk allergy with the use of double-blind, placebo controlled food challenge test in adolescents and adult patients suffering from atopic dermatitis exist. Aim: To evaluate the occurrence of cow’s milk allergy in adolescents and adults suffering from atopic dermatitis. Method: Altogether 179 persons suffering from atopic dermatitis were included in the study: 51 men and 128 women entered the study with the average age of 26.2 (s.d. 9.5 years). Complete dermatological and allergological examinations were performed. Results: The positive results in specificIgE and in skin prick tests were recorded in 12% of patients. According to the open exposure tests and double-blind, placebo controlled food challenge tests these patients are only sensitized to cow’s milk without clinical symptoms of allergy. Double-blind, placebo controlled food challenge test confirmed food allergy to cow milk only in one patient (worsening of atopic dermatitis), the oral allergy syndrome was observed in another one patient, occurrence of this allergy was altogether 1.1%. Conclusion: Cow’s milk allergy rarely plays a role in the worsening of atopic dermatitis in adolescent and adult patients.

Sign in / Sign up

Export Citation Format

Share Document