scholarly journals Evaluating the effects of probiotics in pediatrics with recurrent abdominal pain

2020 ◽  
Vol 63 (12) ◽  
pp. 485-490 ◽  
Author(s):  
Parisa Rahmani ◽  
Azin Ghouran-orimi ◽  
Farzaneh Motamed ◽  
Alireza Moradzadeh
Keyword(s):  
Abdominal Pain ◽  
Lactobacillus Reuteri ◽  
Functional Gastrointestinal Disorders ◽  
Recurrent Abdominal Pain ◽  
Placebo Treatment ◽  
Functional Abdominal Pain ◽  
Double Blind ◽  
Probiotic Treatment ◽  
Rome Iii ◽  
Irritable Bowel

Background: Recurrent abdominal pain (RAP) is one of the frequent complaints in general practice, particularly in pediatrics and is among the common cause of referral to gastroenterology clinics.Purpose: This study is designed to investigate the effects of probiotics for the treatment of RAP and desired therapeutic outcomes.Methods: One hundred twenty-five children with the diagnosis of RAP according to Rome III criteria for irritable bowel syndrome (IBS), functional abdominal pain (FAP), functional dyspepsia (FD), and abdominal migraine (AM), were enrolled in this double-blind randomized controlled trial.Results: Sixty-five subjects received probiotics, and others received placebo treatment for 4 weeks. <i>Lactobacillus reuteri</i> was therapeutically effective in 32 patients compared to 8 patients, responding to the placebo treatment. Compared to baseline, all pain-related variables showed a significant reduction for the IBS and FD at the end of the 4th week. However, it did not respond well in FAP and AM groups. Pain-related outcomes such as, frequency of the pain, severity, and duration of the pain were decreased following the probiotic treatment. No therapeutic response was seen in AM group after the administration of probiotics. <i>L. reuteri</i> significantly led to pain relief in the overall population, and also in FAP, FD, and IBS subgroups.Conclusion: <i>L. reuteri</i> probiotics are likely to lead to RAP relief and can be recommended for the treatment of functional gastrointestinal disorders.

scholarly journals Probiotics on Pediatric Functional Gastrointestinal Disorders

Nutrients ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 1836 ◽  
Author(s):  
Anna Pärtty ◽  
Samuli Rautava ◽  
Marko Kalliomäki
Keyword(s):  
Abdominal Pain ◽  
Lactobacillus Reuteri ◽  
Functional Gastrointestinal Disorders ◽  
Functional Constipation ◽  
Current Evidence ◽  
Infantile Colic ◽  
Functional Abdominal Pain ◽  
Single Strain ◽  
Potential Association ◽  
Irritable Bowel

The potential association between gut microbiota perturbations and childhood functional gastrointestinal disturbances opens interesting therapeutic and preventive possibilities with probiotics. The aim of this review was to evaluate current evidence on the efficacy of probiotics for the management of pediatric functional abdominal pain disorders, functional constipation and infantile colic. Thus far, no single strain, combination of strains or synbiotics can be recommended for the management of irritable bowel syndrome, functional abdominal pain or functional constipation in children. However, Lactobacillus reuteri DSM 17938 may be considered for the management of breastfed colic infants, while data on other probiotic strains, probiotic mixtures or synbiotics are limited in infantile colic.

scholarly journals Gluten and Functional Abdominal Pain Disorders in Children

Nutrients ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1491 ◽  
Author(s):  
Alejandro Llanos-Chea ◽  
Alessio Fasano
Keyword(s):  
Abdominal Pain ◽  
Pediatric Patients ◽  
Functional Gastrointestinal Disorders ◽  
Gastrointestinal Symptoms ◽  
Gluten Sensitivity ◽  
Gluten Free ◽  
Functional Abdominal Pain ◽  
Adults And Children ◽  
Small Intestinal ◽  
Irritable Bowel

In children, functional gastrointestinal disorders (FGIDs) are common at all ages. Consumption of certain foods, particularly gluten, is frequently associated with the development and persistence of FGIDs and functional abdominal pain disorders (FAPDs) in adults and children. However, this association is not well defined. Even without a diagnosis of celiac disease (CD), some people avoid gluten or wheat in their diet since it has been shown to trigger mostly gastrointestinal symptoms in certain individuals, especially in children. The incidence of conditions such as non-celiac gluten sensitivity (NCGS) is increasing, particularly in children. On the other hand, CD is a chronic, autoimmune small intestinal enteropathy with symptoms that can sometimes be mimicked by FAPD. It is still unclear if pediatric patients with irritable bowel syndrome (IBS) are more likely to have CD. Abdominal, pain-associated FGID in children with CD does not seem to improve on a gluten-free diet. The threshold for gluten tolerance in patients with NCGS is unknown and varies among subjects. Thus, it is challenging to clearly distinguish between gluten exclusion and improvement of symptoms related solely to functional disorders.

Irritable bowel syndrome

2020 ◽  
pp. 2951-2959
Author(s):  
Adam D. Farmer ◽  
Qasim Aziz
Keyword(s):  
Irritable Bowel Syndrome ◽  
Abdominal Pain ◽  
Recurrent Abdominal Pain ◽  
Bowel Habit ◽  
Western World ◽  
Older Individuals ◽  
Butyl Bromide ◽  
Rome Iii ◽  
Fermentable Carbohydrates ◽  
Irritable Bowel

Symptoms suggestive of disturbed lower gastrointestinal function without adequate explanation are very common in adults in the Western world, up to 15% of whom experience such symptoms at any one time, although most do not seek medical advice. The currently used terms are best viewed as an attempt to provide some clinically useful, rather than pathophysiologically accurate, categorization of patients and their symptoms based on disordered gut–brain interactions. Irritable bowel syndrome is defined according to the Rome III criteria as recurrent abdominal pain or discomfort associated with a change in bowel habit for at least 6 months, with symptoms experienced on at least 3 days of at least 3 months. Many subtypes are recognized. Routine haematological and biochemical screening is usually performed on the assumption that it will be normal. Features that raise the suspicion of organic disease and indicate a need for further investigation include the onset of symptoms in middle-aged or older individuals, weight loss, or blood in the stool. Management remains empirical: no single pharmacological agent or group of agents has ever been found to be consistently effective. The principal task of the physician is to provide explanation and reassurance (sometimes supplemented by psychological treatments), but particular symptoms are often treated as follows: (1) constipation—defecation may be eased by supplementary dietary fibre and poorly absorbed fermentable carbohydrates which increase faecal bulk and soften the stool; osmotic laxatives and enemas are used for the severely constipated patient, as well as more novel agents; (2) diarrhoea—attention to diet is often helpful, as are simple antidiarrhoeal agents; and (3) abdominal pain—antispasmodics (e.g. hyoscine butyl bromide) are frequently used, as are antidepressants.

scholarly journals Functional Abdominal Pain Disorders in Children

2021 ◽  
Vol 22 (1) ◽  
pp. 60-65
Author(s):  
Muzal Kadim
Keyword(s):  
Abdominal Pain ◽  
Life Experiences ◽  
Major Change ◽  
Anxiety And Depression ◽  
Functional Abdominal Pain ◽  
Negative Experiences ◽  
Not Otherwise Specified ◽  
Rome Iii ◽  
Irritable Bowel ◽  
Rome Iv

Diagnostic criteria for functional abdominal pain has developed in the last decade, from the Rome III criteria to the Rome IV criteria. The major change was in the phrase "abdominal pain related gastrointestinal disorders" to "functional abdominal pain disorders (FAPD)". According to Rome IV criteria, FAPD  are divided into functional dyspepsia (FD), irritable bowel syndrome (IBS), abdominal migraine, and functional abdominal pain-not otherwise specified (FAP-NOS). In order to diagnose FAPD, it is important to pay attention to alarm signs that can indicate organic abnormalities. The pathophysiology of FAPD was a complex interaction between psychosocial, genetic, environmental and life experiences of children through the gut brain axis. The risk factors for functional abdominal pain in children include psychological factors including anxiety and depression, stress conditions, negative experiences, and socioeconomic status.  

scholarly journals Risk factors of recurrent abdominal pain in adolescents

2021 ◽  
Vol 61 (3) ◽  
pp. 141-8
Author(s):  
Muzal Kadim ◽  
Anjar Setiani ◽  
Aryono Hendarto
Keyword(s):  
Risk Factors ◽  
Abdominal Pain ◽  
High School Students ◽  
Junior High School ◽  
Family Income ◽  
Recurrent Abdominal Pain ◽  
Functional Abdominal Pain ◽  
School Students ◽  
Female Age ◽  
Irritable Bowel

Background Recurrent abdominal pain is 2-4% of all cases encountered by pediatricians. Risk factors vary among countries. There is no data on prevalence and risk factors of recurrent abdominal pain in adolescents in Indonesia. Objective To evaluate prevalence and risk factors of recurrent abdominal pain in junior high school students. Methods A cross-sectional study was performed among junior high school students in South Jakarta who experienced recurrent abdominal pain according to Roma III criteria. Students allowed by their parents to participate to this study were asked to complete a Roma III questionnaire. Data about sociodemographic and history of recurrent abdominal pain among the parents were also collected using a questionnaire. ResultsThree hundred ninety-six adolescents participated in this study, 17.2% among them  experiencing recurrentabdominal pain. Irritable bowel syndrome (IBS) was the most common type (42.6%), followed by functional dyspepsia (30.9%), functional abdominal pain syndrome (11.8%), functional abdominal pain (10.3%), and abdominal migraine (4.4%). The risk factor most responsible was anxious personality (OR 3.86; 95%CI 2.05 to 7.29, P<0.001). Other risk factors that contribute were female, age > 13 years, and middle to lower family income. Conclusions Prevalence of recurrent abdominal pain in adolescents is 17.2%. Irritable bowel syndrome is the most common type. The risk factors are anxious personality, female, age > 13 years, and middle to lower family income.

Lactobacillus reuteri DSM 17938 is effective in the treatment of functional abdominal pain in children: Results of the double-blind randomized study

2020 ◽  
Vol 39 (12) ◽  
pp. 3645-3651
Author(s):  
Oleg Jadrešin ◽  
Sara Sila ◽  
Ivana Trivić ◽  
Zrinjka Mišak ◽  
Sanja Kolaček ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Lactobacillus Reuteri ◽  
Randomized Study ◽  
Functional Abdominal Pain ◽  
Double Blind
Sign in / Sign up

Export Citation Format

Share Document