scholarly journals Comparison of Serum Zinc Levels Measured by Inductively Coupled Plasma Mass Spectrometry in Preschool Children with Febrile and Afebrile Seizures

2012 ◽  
Vol 32 (3) ◽  
pp. 190-193 ◽  
Author(s):  
Jun-Hwa Lee ◽  
Jeong Hyun Kim
Keyword(s):  
Mass Spectrometry ◽  
Preschool Children ◽  
Inductively Coupled Plasma ◽  
Serum Zinc ◽  
Inductively Coupled ◽  
Plasma Mass Spectrometry ◽  
Zinc Levels ◽  
Serum Zinc Levels

Decreased Serum Hepatocyte Growth Factor (HGF) in Individuals with Schizophrenia Normalizes after Zinc and B-6 Therapy

2010 ◽  
Vol 3 ◽  
pp. PRI.S6145
Author(s):  
A.J. Russo ◽  
Robert deVito
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Serum Levels ◽  
Age And Gender ◽  
Inductively Coupled ◽  
Plasma Mass Spectrometry ◽  
And Gender ◽  
Zinc Levels ◽  
Hepatocyte Growth ◽  
Post Therapy

Aim To assess serum HGF concentration in individuals with schizophrenia and investigate the efficacy of zinc and B-6 therapy on these levels. Subjects and methods Serum from 18 individuals diagnosed with schizophrenia and 19 age and gender similar controls ( P = 0.18) were tested for HGF concentration using ELISAs, and tested for copper and zinc plasma levels using inductively-coupled plasma-mass spectrometry. Results HGF serum levels of individuals with schizophrenia, before zinc and B-6 therapy, were significantly lower than age and gender similar controls ( P = 0.016), and significantly lower in schizophrenia patients pre-therapy compared to post therapy ( P = 0.028). HGF levels normalized (reached levels similar to controls) post-therapy. Zinc levels in these same individuals also normalized, and perceived symptoms, particularly anxiety ( P = 0.03), improved significantly after therapy. Discussion These results suggest an association between low HGF levels and schizophrenia and demonstrate that zinc and B-6 therapy may be associated with the normalization of HGF levels and perceived improvement in symptoms.

Single Particle Inductively Coupled Plasma Mass Spectrometry: Investigating Nonlinear Response Observed in Pulse Counting Mode and Extending the Linear Dynamic Range by Compensating for Dead Time Related Count Losses on a Microsecond Timescale

2019 ◽  
Author(s):  
Ingo Strenge ◽  
Carsten Engelhard
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Nonlinear Response ◽  
Dynamic Range ◽  
Dead Time ◽  
Inorganic Nanoparticles ◽  
Linear Dynamic Range ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry

<p>The article demonstrates the importance of using a suitable approach to compensate for dead time relate count losses (a certain measurement artefact) whenever short, but potentially strong transient signals are to be analysed using inductively coupled plasma mass spectrometry (ICP-MS). Findings strongly support the theory that inadequate time resolution, and therefore insufficient compensation for these count losses, is one of the main reasons for size underestimation observed when analysing inorganic nanoparticles using ICP-MS, a topic still controversially discussed.</p>

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