scholarly journals Evaluation of the Protective Effect of an Ophthalmic Viscosurgical Device on the Ocular Surface in Dry Eye Patients during Cataract Surgery

2019 ◽  
Vol 33 (5) ◽  
pp. 467 ◽  
Author(s):  
Do Yeh Yoon ◽  
Joo Hyun Kim ◽  
Hyun Sun Jeon ◽  
Hee Eun Jeon ◽  
Sang Beom Han ◽  
...  
Keyword(s):  
Protective Effect ◽  
Cataract Surgery ◽  
Dry Eye ◽  
Ocular Surface ◽  
Ophthalmic Viscosurgical Device

scholarly journals Cataract surgery and dry eye disease: A review

2020 ◽  
Vol 30 (5) ◽  
pp. 840-855
Author(s):  
Khayam Naderi ◽  
Jack Gormley ◽  
David O’Brart
Keyword(s):  
Cataract Surgery ◽  
Dry Eye ◽  
Ocular Surface ◽  
Dry Eye Disease ◽  
Current Evidence ◽  
Cochrane Library ◽  
Eye Disease ◽  
Controlled Trials ◽  
Ovid Medline ◽  
Accuracy Of Measurements

Aim To review published literature concerning cataract surgery and dry eye disease (DED). Methods A search was undertaken using the following: PubMed (all years), Web of Science (all years), Ovid MEDLINE(R) (1946 to 12 December 2019), Ovid MEDLINE(R) Daily Update 10 December 2019, MEDLINE and MEDLINE non-indexed items, Embase (1974–2019, week 49), Ovid MEDLINE (R) and Epub Ahead of Print, In-Process and Other Non-Indexed Citations and Daily (1946 to 12 December 2019), CENTRAL (including Cochrane Eyes and Vision Trials Register; Cochrane Library: Issue 12 of 12 December 2019), metaRegister of Controlled Trials (mRCT) ( www.controlled-trials.com ), ClinicalTrials.gov ( www.clinicaltrial.gov ) and WHO International Clinical Trials Registry Platform ( www.who.int/ictrp/search/en ). Search terms included ‘cataract surgery’, ‘phacoemulsification’ and ‘cataract extraction’, combined with ‘dry eyes’ and ‘ocular surface’. Relevant in-article references not returned in our searches were also considered. Results Publications identified included systematic reviews, meta-analysis, randomized controlled trials, cohort studies, case series and laboratory-based studies. Published data highlighting the burden of DED both prior and following cataract surgery were reviewed as well as studies highlighting the effects of cataract surgery on the ocular surface, intra-operative measures to reduce deleterious effects on the ocular surface and current evidence on the management options of post-operative DED. Conclusions DED is common and can be exacerbated by cataract surgery. Ophthalmologists need to assess for pre-existing DED and instigate treatment before surgery; be aware of reduced accuracy of measurements for surgical planning in the presence of DED; limit intra-operative surgical factors damaging to the ocular surface; and consider management to reduce DED post-operatively.

scholarly journals Discrepancies in Persistent Dry Eye Signs and Symptoms in Bilateral Pseudophakic Patients

2019 ◽  
Vol 8 (2) ◽  
pp. 211 ◽  
Author(s):  
Akiko Hanyuda ◽  
Masahiko Ayaki ◽  
Kazuo Tsubota ◽  
Kazuno Negishi
Keyword(s):  
Cataract Surgery ◽  
Dry Eye ◽  
Ocular Surface ◽  
Bright Light ◽  
Signs And Symptoms ◽  
Clinical Tests ◽  
Blurred Vision ◽  
Body Sensation ◽  
Ocular Fatigue ◽  
Fatigue Sensitivity

Despite the increased awareness of early prophylaxis and treatment for dry eye disease (DED) during the first few weeks after cataract surgery, the chronic effect of cataract surgery on the risk of ocular surface abnormalities has not been fully explored. This study was to assess the prevalence of DE subjective symptoms and clinical tests according to the cataract surgery. A total of 172 patients who underwent bilateral cataract surgeries at least 5 months before the recruitment date and 1225 controls with no cataracts were evaluated for their subjective DE symptoms (dry sensation, foreign-body sensation, ocular pain, ocular fatigue, sensitivity to bright light, and blurred vision) and ophthalmic parameters (tear break-up time, keratoconjunctival staining scores, and maximum blinking interval). The presence of subjective DE symptoms was generally inversely associated with cataract surgeries, whereas abnormal clinical tests were more pronounced among postsurgical cataract patients than among controls. Pseudophakic patients showed a 57% increased prevalence of severe keratoconjunctivitis, compared to controls (P = 0.02). In contrast, among subjective DE symptoms, significantly lower odds of sensitivity to bright light were detected among cases than controls; the multivariable-adjusted odds ratio (95% confidence interval) comparing pseudophakic patients with noncataract patients was 0.56 (0.34–0.92) (P = 0.02). In conclusion, persistent tear instability and corneal epitheliopathy were found even at several months or more after cataract surgery. This study demonstrates the importance of evaluating ocular surface conditions in pseudophakic patients, even if they lack DE symptoms.

scholarly journals Effectiveness and Optical Quality of Topical 3.0% Diquafosol versus 0.05% Cyclosporine A in Dry Eye Patients following Cataract Surgery

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Jang Hoon Lee ◽  
In Seok Song ◽  
Kyoung Lae Kim ◽  
Sam Young Yoon
Keyword(s):  
Cataract Surgery ◽  
Dry Eye ◽  
Cyclosporine A ◽  
Ocular Surface ◽  
Ophthalmic Solution ◽  
Optical Quality ◽  
Ocular Surface Disease Index ◽  
Staining Score ◽  
Surface Staining

Purpose.To evaluate the effectiveness and optical quality of 3.0% topical diquafosol versus 0.05% cyclosporine A in dry eye patients following cataract surgery.Methods.In total, 40 eyes of 40 patients newly diagnosed with dry eye syndrome 1 week after cataract surgery were randomized to receive either 3.0% diquafosol ophthalmic solution six times daily or 0.05% cyclosporine A twice daily for 3 months. Outcome measures were tear film break-up time (TBUT), results on Schirmer 1 test, ocular surface staining score, the ocular surface disease index (OSDI) score, and higher-order aberrations (HOAs). Measurements were taken at baseline and at 1, 2, and 3 months.Results.In the diquafosol group, TBUT showed higher outcomes than the cyclosporine A group at 1 and 3 months. Both groups showed increased scores on Schirmer 1 test. The ocular surface staining score decreased in all periods in both groups. Vertical coma and total HOAs decreased more in the cyclosporine A group than in the diquafosol group at 3 months.Conclusion.Both 3.0% diquafosol and 0.05% cyclosporine A were effective in treating dry eye after cataract surgery. Diquafosol was more effective in increasing the tear secretion, but cyclosporine A was more effective in improving optical aberrations.

The effect of tea tree oil on dry eye treatment after phacoemulsification cataract surgery: A randomized clinical trial

2019 ◽  
Vol 30 (6) ◽  
pp. 1314-1319 ◽  
Author(s):  
Mehrdad Mohammadpour ◽  
Siamak Maleki ◽  
Masoud Khorrami-Nejad
Keyword(s):  
Treatment Group ◽  
Cataract Surgery ◽  
Dry Eye ◽  
Ocular Surface ◽  
Disease Index ◽  
Ocular Surface Disease ◽  
Tea Tree Oil ◽  
Ocular Surface Disease Index ◽  
Tea Tree ◽  
Break Up

Purpose: To evaluate the effect of eyelid scrubbing with eye shampoo containing tea tree oil on dry eye disease following phacoemulsification cataract surgery. Methods: This prospective triple-blinded randomized clinical trial was performed on 62 eyes of 62 patients. Patients were randomly assigned to two groups—(1) treatment group: for 33 patients in the treatment group, artificial tears, topical steroid drops, and eye shampoos with tea tree oil and (2) for 29 patients in the control group, artificial tears, topical steroids, and eye shampoos without tea tree oil were used. In the first and second (after 1 month) follow-up visits, microscopic Demodex examination, refraction, corrected distance visual acuity, the ocular surface disease index score (by the questionnaire), Schirmer test, tear break-up time test, and osmolarity of tears (by TearLab) were recorded in treatment and control groups. Results: The mean age of patients was 66.37 ± 8.83 (range: 37–82) years, of which 49 (79%) were female and 13 (21%) were male. The results showed a significant improvement in tear break-up time test, corrected distance visual acuity, osmolarity, and ocular surface disease index score in both groups ( p < 0.05). However, the number of Demodex decreases significantly only in the treatment group after treatment ( p <0.001). Tear break-up time, osmolarity, and ocular surface disease index scores in the treatment group were significantly better than the control group ( p < 0.05). However, there was no significant difference between the two groups in the pre- and post-Schirmer test results ( p > 0.05). Conclusion: Eyelid scrubbing with eye shampoo containing tea tree oil is recommended for dry eye treatment after cataract surgery, especially decrease in the number of Demodex.

scholarly journals Acute corneal perforation 1 week following uncomplicated cataract surgery: the implication of undiagnosed dry eye disease and topical NSAIDs

2019 ◽  
Vol 11 ◽  
pp. 251584141986950 ◽  
Author(s):  
Darren Shu Jeng Ting ◽  
Saurabh Ghosh
Keyword(s):  
Rheumatoid Arthritis ◽  
Cataract Surgery ◽  
Dry Eye ◽  
Ocular Surface ◽  
Preoperative Assessment ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Corneal Perforation ◽  
Inflammatory Drugs ◽  
Topical Nsaids

Dry eye disease is a common ocular surface disease in patients who are undergoing cataract surgery. The significance of dry eye disease is often underestimated or overlooked during preoperative assessment of cataract. We report an 80-year-old patient, with a background of seropositive rheumatoid arthritis and diabetes, who presented with an acute corneal melt and perforation associated with undiagnosed dry eye disease and use of topical ketorolac 1 week following an uncomplicated cataract surgery. The patient underwent repeated corneal gluing for corneal perforation and was subsequently diagnosed and treated for bilateral moderate-severe dry eye disease. This case highlights the importance of meticulous preoperative assessment and management of the ocular surface, especially in patients with systemic diseases such as rheumatoid arthritis and diabetes prior to cataract surgery. The implication of the use of topical nonsteroidal anti-inflammatory drugs following cataract surgery – which might have contributed to the process of corneal melt in our case – is also discussed.

Dry-eye and inflammation of the ocular surface after cataract surgery

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Carlo Cagini ◽  
Giampiero Di Lascio ◽  
Giovanni Torroni ◽  
Marco Mariniello ◽  
Giulia Meschini ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Dry Eye ◽  
Ocular Surface

Hoornvliesbeschadiging na cataractchirurgie: belang van het droge-ogensyndroom en topische NSAID’s en oppuntstelling van de behandeling

2021 ◽  
Author(s):  
A. POTVIN ◽  
D. ROELS
Keyword(s):  
Risk Factors ◽  
Cataract Surgery ◽  
Dry Eye ◽  
Ocular Surface ◽  
Dry Eye Disease ◽  
Autologous Serum ◽  
Eye Disease ◽  
Amniotic Membrane Transplantation ◽  
Topical Medication ◽  
Anti Inflammatory

Dry eye disease and cataract surgery: identification of risk factors for corneal damage and optimisation of treatment Various factors in the perioperative cataract surgery period can synergistically initiate a vicious inflammatory cycle of dry eye disease (DED) and tissue damage, with dire consequences. A careful anamnesis and preoperative assessment of the ocular surface can reveal some of the risk factors and facilitate an appropriate perioperative approach. Attention should be paid to DED and associated conditions, such as Meibomian gland dysfunction, as these conditions are very common. In the postoperative period, it is wise to avoid preserved topical medication, as well as to use topical medication that may be toxic to the ocular surface, such as non-steroidal anti-inflammatory drugs (NSAIDs), with care in specific cases. The treatment of DED and its complications consists primarily of the careful use of lubricating, antibiotic and anti-inflammatory agents. In serious DED cases, autologous serum promotes tissue regeneration by promoting epithelialisation and stromal recovery, and can be a useful adjunct to the first-line treatment. In extreme and rare cases, DED can, in combination with the use of topical NSAIDs and other risk factors, lead to sight-threatening complications, such as corneal melting. A surgical treatment consisting of conjunctival flap transplantation, amniotic membrane transplantation, gluing of the cornea or tectonic keratoplasty may be necessary when perforation is imminent.

scholarly journals Dry Eye Epidemiology in Patients before Cataract Surgery

2020 ◽  
Vol 17 (2) ◽  
pp. 281-289
Author(s):  
S. N. Sakhnov ◽  
S. V. Yanchenko ◽  
A. V. Malyshev ◽  
V. V. Dashina ◽  
A. R. Ceeva ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Cataract Surgery ◽  
Dry Eye ◽  
Ocular Surface ◽  
Surface Condition ◽  
Significant Risk ◽  
Eye Drops ◽  
Local Risk ◽  
Cataract Patients

Purpose. To evaluate the prevalence, clinical and pathogenetic variants and statistically significant risk factors of dry eye (DE) in patients before cataract surgery. Patients and Methods. 600 age-related and complicated cataract patients (70.6 ± 7.8 years old; 269 men, 331 women) were examined. Visometry and biomicroscopy with photographic recording of the lens state and assessment of its opacities according to the LOCS III classification were used to cataract revealing. OSDI testing, lipid interferential test, TBUT, Shirmer-1, -2 tests, visual and OCT meniscometry, evaluation of epitheliopaty and microerosion (with vital staining), compression Norn test in Korb modification, visual and OCT LIPCOF assessment, lid viper epitheliopathy evaluation, anterior segment of the eye photoregistration with computer morphometry were performed to assess the ocular surface condition. The structure of the DE risk factors, was studied both in DE patients and non-DE subjects with calculation of the Pearson xi-square test. To estimate the strength of the connection between the etiological condition and the DE, the normalized value of the Pearson coefficient (C´) was used. Results. The dry eye prevalence was 53.2 % (of them, 25.5 % was mild, 27.7 % — moderate, by Brzhesky). Subclinical DE prevalence was 27 %. Clinical and pathogenetic variants of mild DE included: isolated lipid deficiency (71.9 %), lipid-mucin deficiency (28.1 %). In patients with moderate DE were identified: aqueous-lipid-mucin deficiency (54.8 %), aqueous-lipid deficiency (37.95 %), isolated aqueous deficiency (7.2 %). The most significant systemic-organ DE risk factors were: diabetes mellitus (C´ = 0.302; in 18.8 % DE patients), female sex (C´ = 0.240; in 62.1 % de patients), allergy (С´ = 0.233; in 23.2 % DE patients). Local risk factors most significantly associated with DE were: meibomian glands dysfunction (С´ = 0.58; in 77.7 % DE patients), chronic blepharitis (С´ = 0.233; in 23.2 % DE patients), pterygium (С´ = 0.276; in 13.2 % DE patients), allergic conjunctivitis (С´ = 0.21; in 21.3 % DE patients). Among the exogenous risk factors, the most significant were: the use of medication affecting tear production or tear film stability (С´ = 0.485; in 89.03 % DE patients), preservative eye drops instillation (С´ = 0.2975; in 56.1 % DE patients). Conclusion. In our opinion, data on the high DE prevalence in cataract patients (53.2 %) should be taken into account when planning cataract surgery, since perioperative correction of the ocular surface condition can increase the surgical treatment efficiency, predictability and safety. The data on the structure of significant risk factors and clinical and pathogenetic DE variants in cataract patients can be the basis for the development of measures to ensure timely DE detection and implementation of reasonable therapy. The risk factor most significantly associated with DE in cataract patients was the meibomian gland dysfunction (MGD) (Pearson xi-square test = 88.542, p < 0.001, С´ = 0.58; “relatively strong” strength). Considering the modifiability of this risk factor (MGD), as well as its high prevalence (77.7 %), it can be considered that eye lids hygiene may be a reasonable therapy in most DE and cataract patients before phacoemulsification.

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