scholarly journals Ocular and Facial Herpes Zoster and Meningitis in an Adult after Zoster Vaccination

2021 ◽  
Vol 62 (12) ◽  
pp. 1663-1666
Author(s):  
Ji-Ho Choi ◽  
Min Ahn ◽  
Nam Chun Cho ◽  
In Cheon You
Keyword(s):  
Herpes Zoster ◽  
Antiviral Treatment ◽  
Brain Magnetic Resonance Imaging ◽  
Severe Headache ◽  
Slit Lamp ◽  
Resonance Imaging ◽  
Chain Reaction ◽  
Varicella Zoster ◽  
Vesicular Rash ◽  
Polymerase Chain

Purpose: To report a case of ocular and facial herpes zoster and meningitis after herpes zoster vaccination.Case summary: A 60-year-old man was administered Zostavax® on his left arm; he developed a vesicular rash over his left eye and forehead 4 days afterwards. He started antiviral drugs for the rash, and visited the hospital for severe headache and spread of the rash to involve the tip of his nose, face, and palate by day 7. He was taking Synthyroid® (Bukwang Pharmaceuticals, Seoul, Korea) since his thyroidectomy for thyroid cancer 6 years ago. He had never been diagnosed with chickenpox, but had an episode of red facial rash in childhood. Slit-lamp examination revealed conjunctival chemosis, hyperemia, and a pseudodendrite in the peripheral cornea. The anterior chamber was quiet, and there were no significant findings on his brain magnetic resonance imaging. Varicella zoster virus was detected in the cerebrospinal fluid by polymerase chain reaction. The patient was treated with oral acyclovir drugs and topical ganciclovir, levofloxacin, and bromfenac. One week later, the pseudodendrite disappeared and conjunctival chemosis improved. There was no recurrence during 6 months follow-up.Conclusions: Reactivation of ocular or facial herpes zoster or meningitis after zoster vaccination may occur, rarely. Immediate antiviral treatment is required in these cases.

scholarly journals Does Herpes Zoster Increase the Risk of Stroke and Myocardial Infarction? A Comprehensive Review

2019 ◽  
Vol 8 (4) ◽  
pp. 547 ◽  
Author(s):  
Ping-Hsun Wu ◽  
Yun-Shiuan Chuang ◽  
Yi-Ting Lin
Keyword(s):  
Myocardial Infarction ◽  
Herpes Zoster ◽  
Antiviral Treatment ◽  
Cardiac Events ◽  
Herpes Zoster Ophthalmicus ◽  
Varicella Zoster ◽  
Vesicular Rash ◽  
Ischemic Complications ◽  
One Year ◽  
Ischemic Attack

Herpes zoster (HZ) caused by varicella zoster virus (VZV) reactivation is characterized as a vesicular rash of unilateral distribution that can also cause multiple complications; such as post-herpetic neuralgia; ophthalmic zoster; and other neurological issues. VZV can also increase incident hemorrhagic or ischemic complications by causing inflammatory vasculopathy. Thus; emerging epidemiological and clinical data recognizes an association between HZ and subsequent acute strokes or myocardial infarction (MI). This study reviewed published articles to elucidate the association between HZ and cerebrovascular and cardiac events. Individuals exposed to HZ or herpes zoster ophthalmicus had 1.3 to 4-fold increased risks of cerebrovascular events. Higher risks were noted among younger patients (age < 40 years) within one year after an HZ episode. The elevated risk of CV events diminished gradually according to age and length of time after an HZ episode. The putative mechanisms of VZV vasculopathy were also discussed. Several studies showed that the development of herpes zoster and herpes zoster ophthalmicus increased the risks of stroke; transient ischemic attack; and acute cardiac events. The association between VZV infection and cardiovascular events requires further studies to establish the optimal antiviral treatment and zoster vaccination to reduce zoster-associated vascular risk

scholarly journals Malacoplakia of the Uterine Cervix: A Case Report

Pathogens ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 343
Author(s):  
Adela Saco ◽  
Natalia Rakislova ◽  
Lorena Marimon ◽  
Aureli Torne ◽  
Berta Diaz-Feijoo ◽  
...  
Keyword(s):  
Uterine Cervix ◽  
Genital Tract ◽  
Vaginal Bleeding ◽  
Female Genital Tract ◽  
Granulomatous Inflammation ◽  
Resonance Imaging ◽  
Chain Reaction ◽  
Polymerase Chain ◽  
Cervical Tumors ◽  
Female Genital

Malacoplakia is an uncommon chronic granulomatous inflammation that rarely affects the female genital tract. A case of a 78-year-old woman with malacoplakia involving the uterine cervix and the vagina is described. The patient complained of vaginal bleeding. Clinically, a 13-mm mass was detected in the cervix, which was confirmed by ultrasound scan and magnetic resonance imaging. Histological examination showed a dense histiocytic infiltrate with abundant Michaelis–Gutmann bodies involving the uterine cervix and the upper vagina. The presence of Escherichia coli was confirmed in the lesion by immunohistochemistry and polymerase chain reaction. Only 12 cases of cervical malacoplakia have been reported to date. This condition should be included in the differential diagnosis of cervical tumors.

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