scholarly journals Safety and efficacy of the combination of T-DM1 with radiotherapy of the central nervous system in a patient with HER2-positive metastatic breast cancer: case study and review of the literature

2015 ◽  
Vol 11 ◽  
Author(s):  
Giuliano Santos Borges ◽  
Rodrigo Kraft Rovere ◽  
Stéphanie Mereniuk Kappel Dias ◽  
Fernando Henrique Chong ◽  
Mayara dos Santos Morais
Breast Care ◽  
2013 ◽  
Vol 8 (5) ◽  
pp. 368-370 ◽  
Author(s):  
Lisa Richters ◽  
Monika Ortmann ◽  
Michael Faust ◽  
Stefan Krämer ◽  
Peter Mallmann ◽  
...  

2021 ◽  
Vol 1 (31) ◽  
pp. 20-24
Author(s):  
M. V. Kalugin ◽  
K. A. Ivanova ◽  
E. I. Borisova ◽  
S. S. Nakhapetyan ◽  
S. L. Gutorov

In most cases triple negative breast cancer is characterized by an aggressive course of disease and early development of resistance to chemotherapy. Thereafter, the late-line treatment choice, usually after anthracyclines and taxanes, is problematic due to the limited amount of effective and low-toxic cytostatics. In our opinion, in this situation the use of eribulin which possesses unique antitumor action mechanisms is a good option. An illustrative case of a pronounced antitumor effect of eribulin in metastatic breast cancer with triple negative phenotype resistant to previous lines of chemotherapy is presented.


2013 ◽  
Vol 37 (4) ◽  
pp. 746-749 ◽  
Author(s):  
Elisa Francone ◽  
Marco J. Nathan ◽  
Federica Murelli ◽  
Maria Santina Bruno ◽  
Enrico Traverso ◽  
...  

Breast Care ◽  
2016 ◽  
Vol 11 (6) ◽  
pp. 424-426 ◽  
Author(s):  
Arpine Gevorgyan ◽  
Giacomo Bregni ◽  
Giulia Galli ◽  
Elisa Zanardi ◽  
Filippo de Braud ◽  
...  

Background: Neuroendocrine carcinoma is an uncommon histology for breast cancer. Case Report: Our patient underwent right quadrantectomy for a neuroendocrine carcinoma in 1984 and had a bone relapse 30 years later. After thorough pathological and immunohistochemical analysis the diagnosis was confirmed and HER2 amplification was observed. Here we discuss the management, rationale and results of HER2-targeted therapy in advanced neuroendocrine breast carcinoma.


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