174. Chemical Information System for Structure-Activity Analysis in Occupational Contact Dermatitis

2002 ◽  
Author(s):  
D. Whaley ◽  
D. Woldemikael ◽  
E. Demchuk
Keyword(s):  
Information System ◽  
Contact Dermatitis ◽  
Activity Analysis ◽  
Chemical Information ◽  
Occupational Contact Dermatitis ◽  
Structure Activity ◽  
Chemical Information System ◽  
Occupational Contact

Modified Plasma Cytokine Profile in Occupational Dermatitis

2020 ◽  
Vol 20 (8) ◽  
pp. 1295-1302
Author(s):  
Alexandra M. Rascu ◽  
Marina R. Otelea ◽  
Cristina Mambet ◽  
Claudia Handra ◽  
Ana I. Neagu ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Fold Increase ◽  
Fibroblast Growth ◽  
Occupational Dermatitis ◽  
Plasma Cytokine ◽  
Growth Differentiation Factor 15 ◽  
Occupational Contact Dermatitis ◽  
Paint Industry ◽  
Pooled Sample ◽  
Occupational Contact

Background: Despite significant progress in the diagnosis of contact dermatitis, the identification by specific tests or biomarkers remains an unsolved issue, particularly when needed for the confirmation of the occupational origin of the disease. Objective: To characterize the plasma proteome profile in occupational dermatitis in workers of paint industry. Methods: The study has a case-control design, comparing exposed workers with and without occupational contact dermatitis, matched for age, gender, occupational history, and comorbidities. An immunological assay (Human XL Cytokine Array Kit – ARY022B, R&D Systems) was used to measure the plasma levels of 105 cytokines and chemokines in a pooled sample of the cases and a pooled sample of the controls. Results: A 1.5-fold increase was noticed for interleukin 3, interleukin 10, and leptin in cases, as compared to controls. Fibroblast growth factor-7 and growth/differentiation factor-15 showed a 1.4-fold increase, while interleukin 19, interleukin 31, and macrophage inflammatory protein 3a.had only a 1.3- fold increase. The leukemia inhibitory factor was the only plasma cytokine that showed a 1.3-fold decrease. All other cytokines had a variation of less than 1.2-fold between cases and controls. Conclusion: The recognition of the molecular signatures is very important for an accurate and indisputable diagnosis of occupational contact dermatitis. In workers from the paint industry, plasma levels of interleukins 3, 10, 13 and 19, fibroblast growth factor-7, and growth/differentiation factor-15, together with leukemia inducible factor, may differentiate subjects with contact dermatitis from those without skin lesions.

Occupational Contact Dermatitis to Penicillium molds on Salami Skin

2011 ◽  
Vol 127 (2) ◽  
pp. AB179-AB179
Author(s):  
F. Wantke ◽  
B. Simon-Nobbe ◽  
V. Pöll ◽  
M. Götz ◽  
R. Jarisch ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Occupational Contact Dermatitis ◽  
Occupational Contact

Incidence and prevalence rates for occupational contact dermatitis in an Australian suburban area

2005 ◽  
Vol 52 (5) ◽  
pp. 254-259 ◽  
Author(s):  
Tessa Keegel ◽  
Jennifer Cahill ◽  
Amanda Noonan ◽  
Shyamali Dharmage ◽  
Helen Saunders ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Suburban Area ◽  
Prevalence Rates ◽  
Occupational Contact Dermatitis ◽  
Occupational Contact

Occupational contact dermatitis from airborne nicergoline

1992 ◽  
Vol 27 (4) ◽  
pp. 256-256 ◽  
Author(s):  
M. Fumagalli ◽  
A. S. Bigardi ◽  
A. Legori ◽  
P. D. Pigatto
Keyword(s):  
Contact Dermatitis ◽  
Occupational Contact Dermatitis ◽  
Occupational Contact

Occupational contact dermatitis from diacetylmorphine (heroin)

2001 ◽  
Vol 45 (2) ◽  
pp. 114-114 ◽  
Author(s):  
P. J. Coenraads ◽  
A. J. Hogen Esch ◽  
R. L. M. A. Prevoo
Keyword(s):  
Contact Dermatitis ◽  
Occupational Contact Dermatitis ◽  
Occupational Contact

PAGODE: The Computer-Based Chemical Information System of CLIN MIDY Research Center

1978 ◽  
Vol 18 (3) ◽  
pp. 140-146
Author(s):  
Samuel Berdugo ◽  
Jean Boitard ◽  
Jean Paul Gervois ◽  
Anne Marie Segretain ◽  
Odile Pietrement
Keyword(s):  
Information System ◽  
Research Center ◽  
Chemical Information ◽  
Computer Based ◽  
Chemical Information System
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