scholarly journals Removing Trigger Point and Balancing Metabolic Reactions Are the Keys to Fatigue, Nerve Pain, Chronic Illness, Diabetes, Fibromyalgia, Alzheimer’s Diseases, Vestibular Disorder, and Neurodegenerative Diseases

2019 ◽  
Vol 4 (6) ◽  
Keyword(s):  
Chronic Illness ◽  
Neurodegenerative Diseases ◽  
Blood Circulation ◽  
Trigger Point ◽  
Vital Role ◽  
The Body ◽  
Vestibular Disorder ◽  
Metabolic Reactions ◽  
Alzheimer’S Diseases

When we talk about the vital role of oxygen, we forget that the vital role of oxygen is to interact with glucose in the cells catalyzed by many enzymes to generate energy. The main source to generate energy in cells is from glucose, enough glucose is as vital as enough oxygen. Poor blood circulation may come from the blocking points in the vessels or from low blood pressure or low blood glucose. In the body, all the billions of cells of all body systems need the energy to have normal functions; which is mainly generated from metabolizing glucose. When the cells hunger for glucose, it can start to use structure stored glucose or stored lipids or polysaccharides or structure lipid or structure protein. To take stored glucose, the body needs good blood circulation and right body temperature. The people with chronic illness often have hormonal imbalanced – which need glucose as the main source of energy also, and poor blood circulation and disorder of thermoregulation. If we do not stop these disorders, these people may have metabolic disorders or metabolic diseases. The main energy source for the cells is from the catabolism of glucose. So any problem for glycemia and oxygen saturation will make the billions of cells of the body are out of balance. During practice Vietnamese Qi gong combining with traditional medicine, the author realizes that in just ten minutes, just by removing trigger point and balancing metabolic reactions, we can deal easily most of the symptoms of fatigue, nerve pain, chronic illness, diabetes, fibromyalgia, Alzheimer’s diseases, Vestibular disorder, and Neurodegenerative Diseases.

Hypothetical Role of Growth Factors to Reduce Intervertebral Disc Degeneration Significantly through Trained Biological Transformations

2020 ◽  
Vol 26 ◽  
Author(s):  
Cristian Muresanu ◽  
Siva G. Somasundaram ◽  
Sergey V. Vissarionov ◽  
Liliya V. Gavryushova ◽  
Vladimir N. Nikolenko ◽  
...  
Keyword(s):  
Growth Factors ◽  
Blood Circulation ◽  
Seminal Fluid ◽  
Prostate Gland ◽  
The Body ◽  
Personal Experiences ◽  
Biological Transformation ◽  
The Mind

Background: From the evidence of failed injection-based growth factor therapies, it has been proposed that a naturally triggered uninterrupted blood circulation of the growth factors would be superior. Objective: We seek to stimulate discussions and more research about the possibility of using the already available growth factors found in the prostate gland and endometrium by starting a novel educable physiology, known as biological transformations controlled by the mind. Methods: We summarized the stretch-gated ion channel mechanism of the cell membrane, and offer several practical methods that can be applied by anyone, in order to stimulate and enhance the blood circulation of the growth factors from the seminal fluid to sites throughout the body. This details the practical application of our earlier published studies about biological transformations. Results: A previously reported single-patient case study has been extended, adding more from his personal experiences continually improving this novel physiological training and extending the ideas from our earlier findings in detail. Conclusion: The biological transformation findings demonstrate the need additional research to establish the benefits of these natural therapies to repair and rejuvenate tissues affected by various chronic diseases or aging processes.

scholarly journals Role of Education and Mentorship in Entrepreneurial Behavior: Mediating Role of Self-Efficacy

2021 ◽  
Vol 12 ◽  
Author(s):  
Binwu Hu ◽  
Qiang Zheng ◽  
Jie Wu ◽  
Zhibin Tang ◽  
Jianchun Zhu ◽  
...  
Keyword(s):  
Self Efficacy ◽  
Vital Role ◽  
The Body ◽  
Survey Study ◽  
Mediating Role ◽  
Farming Community ◽  
Body Of Knowledge ◽  
Behavioral Preferences ◽  
Structured Questionnaire

Farmers have been very precious for societies for ages. Their active experiments, valuable knowledge about their surroundings, environment, and crops’ requirements have been a vital part of society. However, the psychological perspectives have been a hole in the loop of farming. Hence, this study has investigated the antecedents of entrepreneurial behaviors of farmers with the mediating risk of their entrepreneurial self-efficacy (ESE). The population chosen for this study was the farming community of suburbs of China, and a sample size of 300 was selected for the data collection. This is a survey study, where a structured questionnaire was adapted on a five-point Likert scale. The data were collected from the farming community to know their psychological and behavioral preferences about their profession. This study has produced interesting results that education, training, and intrinsic motivation play a vital role in farmers’ ESE, affecting their entrepreneurial behaviors. This study will add to the body of knowledge and provide an eminent path for emerging entrepreneurs to find more mentorship opportunities to overcome the limitations in upcoming endeavors influencing education and training.

Extracellular vesicles, stem cells and the role of miRNAs in neurodegeneration

2021 ◽  
Vol 19 ◽  
Author(s):  
Ayaz M. Belkozhayev ◽  
Minnatallah Al-Yozbaki ◽  
Alex George ◽  
Raigul Ye Niyazova ◽  
Kamalidin O. Sharipov ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neurodegenerative Diseases ◽  
Extracellular Vesicles ◽  
Intercellular Communication ◽  
Direct Consequence ◽  
Therapeutic Benefit ◽  
The Body ◽  
A Cell ◽  
Crucial Information

There are different modalities of intercellular communication governed by cellular homeostasis. In this review, we will explore one of these forms of communication called extracellular vesicles (EVs). These vesicles are released by all cells in the body and are heterogeneous in nature. The primary function of EVs is to share information through their cargo consisting of proteins, lipids and nucleic acids (mRNA, miRNA, dsDNA etc.) with other cells, which have a direct consequence on their microenvironment. We will focus on the role of EVs of mesenchymal stem cells (MSCs) in the nervous system and how these participate in intercellular communication to maintain physiological function and provide neuroprotection. However, deregulation of this same communication system could play a role in several neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, Amyotrophic lateral sclerosis, multiple sclerosis, prion disease and Huntington’s disease. The release of EVs from a cell provides crucial information to what is happening inside the cell and thus could be used in diagnostics and therapy. We will discuss and explore new avenues for the clinical applications of using engineered MSC-EVs and their potential therapeutic benefit in treating neurodegenerative diseases.

scholarly journals Therapeutic Potential of AAV1-Rheb(S16H) Transduction against Neurodegenerative Diseases

2021 ◽  
Vol 22 (6) ◽  
pp. 3064
Author(s):  
Youngpyo Nam ◽  
Gyeong Joon Moon ◽  
Sang Ryong Kim
Keyword(s):  
Neurodegenerative Diseases ◽  
Neurodegenerative Disorders ◽  
Therapeutic Potential ◽  
Neuroprotective Effect ◽  
Active Form ◽  
Mammalian Target Of Rapamycin ◽  
Regulatory System ◽  
Neuronal Population ◽  
Vital Role

Neurotrophic factors (NTFs) are essential for cell growth, survival, synaptic plasticity, and maintenance of specific neuronal population in the central nervous system. Multiple studies have demonstrated that alterations in the levels and activities of NTFs are related to the pathology and symptoms of neurodegenerative disorders, such as Parkinson’s disease (PD), Alzheimer’s disease (AD), and Huntington’s disease. Hence, the key molecule that can regulate the expression of NTFs is an important target for gene therapy coupling adeno-associated virus vector (AAV) gene. We have previously reported that the Ras homolog protein enriched in brain (Rheb)–mammalian target of rapamycin complex 1 (mTORC1) axis plays a vital role in preventing neuronal death in the brain of AD and PD patients. AAV transduction using a constitutively active form of Rheb exerts a neuroprotective effect through the upregulation of NTFs, thereby promoting the neurotrophic interaction between astrocytes and neurons in AD conditions. These findings suggest the role of Rheb as an important regulator of the regulatory system of NTFs to treat neurodegenerative diseases. In this review, we present an overview of the role of Rheb in neurodegenerative diseases and summarize the therapeutic potential of AAV serotype 1 (AAV1)-Rheb(S16H) transduction in the treatment of neurodegenerative disorders, focusing on diseases, such as AD and PD.

Role of BCL-2 Family Proteins in Apoptosis and its Regulation by Nutrients

2020 ◽  
Vol 21 (8) ◽  
pp. 799-806 ◽  
Author(s):  
Chen Zheng ◽  
Ting Liu ◽  
Huihui Liu ◽  
Jing Wang
Keyword(s):  
Cell Death ◽  
Normal Function ◽  
Vital Role ◽  
The Body ◽  
Cell Leukemia ◽  
Nutritional Factors ◽  
Antiapoptotic Proteins ◽  
B Cell Leukemia ◽  
Growth Development

In the body, millions of cells die and proliferate each day to maintain normal function and cooperation of all tissues, organs, and systems. Thus, programmed cell death, or apoptosis, is critical to sustain growth, development, and body health. The vital role of B-cell leukemia/lymphoma-2 (BCL-2) family proteins in apoptosis has been identified. The BCL-2 family includes both pro- and antiapoptotic proteins, which are structurally and functionally related, containing up to four BCL-2 homology (BH) motifs (BH1-4). There are also some nutritional factors that regulate apoptosis via the BCL-2 family proteins. In this review, the BCL-2 family proteins and their apoptosis-inducing mechanism have been discussed, along with the nutrient factors that regulate apoptosis through the BCL-2 family proteins.

Etiologic Factors in Obesity and Leanness

PEDIATRICS ◽  
1958 ◽  
Vol 22 (4) ◽  
pp. 760-760
Keyword(s):  
Cultural Influences ◽  
Juvenile Diabetes ◽  
The Body ◽  
Energy Utilization ◽  
Obese Person ◽  
Juvenile Diabetes Mellitus ◽  
The Past ◽  
Metabolic Systems ◽  
Metabolic Reactions

In recent years the literature placed before the pediatric audience has belabored the role of psychogenic factors in the causation of obesity. This stimulating essay shows promise that this spell is to be broken. In the past the obese person has been pictured as an individual who is the victim of a disordered personality. Insufficient attention has been given to inherent difficulties in the metabolic systems which govern exchange of energy in the body. This paper challenges the concept that obesity is generally due simply to overeating. A review is given of possible variations in efficiency of phosphorylation; aerobiosis versus anaerobiosis; variations in energy utilization and variations in lipogenesis, any of which may be attributes of the person prone to obesity or leanness. It is emphasized that the maintenance of an optimal body weight by an individual is the result of the algebraic sum of 1) hereditary traits affecting metabolic reactions and 2) the environmental and cultural influences, which may act in conjunction with the former to predispose to either obesity or leanness. One may conjecture that we shall ultimately come to view the simple restriction of intake to be as ruthless a therapy for the obese as we have discovered the simple restriction of carbohydrate to be ridiculous as a treatment for juvenile diabetes mellitus.

Role of medicinal plants against neurodegenerative diseases

2021 ◽  
Vol 22 ◽  
Author(s):  
Ritika Luthra ◽  
Arpita Roy
Keyword(s):  
Medicinal Plants ◽  
Neurodegenerative Diseases ◽  
Molecular Mechanisms ◽  
Environmental Changes ◽  
Inflammatory Responses ◽  
Vital Role ◽  
Significant Loss ◽  
Therapeutic Interventions ◽  
Inflammatory Stress

: Diseases with a significant loss of neurons, structurally and functionally are termed as neurodegenerative diseases. Due to the present therapeutic interventions and progressive nature of diseases, a variety of side effects have risen up, thus leading the patients to go for an alternative medication. The role of medicinal plants in such cases has been beneficial because of their exhibition via different cellular and molecular mechanisms. Alleviation in inflammatory responses, suppression of the functionary aspect of pro-inflammatory cytokines like a tumor, improvement in antioxidative properties is among few neuroprotective mechanisms of traditional plants. Variation in transcription and transduction pathways play a vital role in the preventive measures of plants in such diseases. Neurodegenerative diseases are generally caused by depletion of proteins, oxidative and inflammatory stress, environmental changes and so on, with aging being the most important cause. Natural compounds can be used in order to treat neurodegenerative diseases Medicinal plants such as Ginseng, Withania somnifera, Bacopa monnieri, Ginkgo biloba, etc. are some of the medicinal plants for prevention of neurological symptoms. This review deals with the use of different medicinal plants for the prevention of neurodegenerative diseases.

The Role of Traffic-Related Air Pollution on Neurodegenerative Diseases in Older People: An Epidemiological Perspective

2020 ◽  
pp. 1-11
Author(s):  
Rachel Tham ◽  
Tamara Schikowski
Keyword(s):  
At Risk ◽  
Air Pollution ◽  
Environmental Factors ◽  
Neurodegenerative Diseases ◽  
Risk Groups ◽  
Air Pollutant ◽  
The Body ◽  
Design Assessment ◽  
Genetic Characteristics

Traffic-related air pollution is ubiquitous and almost impossible to avoid. It is important to understand the role that traffic-related air pollution may play in neurodegenerative diseases, such as dementia, Alzheimer’s disease, and Parkinson’s disease, particularly among older populations and at-risk groups. There is a growing interest in this area among the environmental epidemiology literature and the body of evidence identifying this role is emerging and strengthening. This review focuses on the principal components of traffic-related air pollutants (particulate matter and nitrogen oxides) and the epidemiological evidence of their contribution to common neurodegenerative diseases. All studies reported are currently observational in nature and there are mixed findings depending on the study design, assessment of traffic-related air pollutant levels, assessment of the neurodegenerative disease outcome, time period of assessment, and the role of confounding environmental factors and at-risk genetic characteristics. All current studies have been conducted in income-rich countries where traffic-related air pollution levels are relatively low. Additional longer-term studies are needed to confirm the levels of risk, consider other contributing environmental factors and to be conducted in settings where air pollution exposures are higher and at-risk populations reside and work. Better understanding of these relationships will help inform the development of preventive measures and reduce chronic cognitive and physical health burdens (cost, quality of life) at personal and societal levels.

scholarly journals Pemberdayaan Masyarakat Di Kelurahan Wonosari Melalui Olahraga

2018 ◽  
Vol 18 (1) ◽  
pp. 111
Author(s):  
Qorby Haqqul Adam
Keyword(s):  
Blood Circulation ◽  
Social Economic ◽  
Active Role ◽  
The Body ◽  
Community Group ◽  
Mutual Cooperation ◽  
Rhythmic Gymnastics ◽  
Education Culture ◽  
The Village

<p>Wonosari is one of the sub-districts in Ngaliyan district, Semarang city. The community in Wonosari Village is a suburban community group. They have low insight and awareness in doing sports. Sports can be used as a development of the potential, character and active role of humans in community life. Sports has benefits in all fields in the community such as education, culture, social, economic and health. Humans have been preoccupied with pragmatism in this age. They do not understand that moving is very important for health and is the most valuable asset they can have. Health is grouped into four types, physically, spiritually, socially and economically healthy. Lack of physical activity and exercise will cause adverse effects on the body. Wonosari people who have solid activities can do some physical activities to just relax muscles and blood circulation such as: cycling, walking early in the morning, sweeping the floor, mutual cooperation in the village every day, and others. If you have enough free time someone can exercise. The types of sports that can be done in the Wonosari Urban community include rhythmic gymnastics, soccer, volleyball, badminton and relaxing walking. Sports also have benefits for physical fitness, achieving spiritual, social and economic health in humans.</p><p> </p><p>Wonosari merupakan salah satu Kelurahan di Kecamatan ngaliyan Kota Semarang. Masyarakat di Kelurahan Wonosari merupakan kelompok masyarakat suburban. Mereka mempunyai wawasan dan kesadaran yang rendah dalam melakukan olahraga. Olahraga dapat dijadikan sebagai pengembangan potensi, karakter dan peran aktif manusia dalam kehidupan bermasyarakat. Olahraga mempunyai manfaat dalam segala bidang di lingkungan masyarakat seperti pendidikan, budaya, sosial, ekonomi dan kesehatan. Manusia telah disibukkan dengan aktivitas pragmatisme pada zaman ini. Mereka tidak mengerti bahwa bergerak sangat penting bagi kesehatan dan menjadi harta yang paling berharga yang dapat mereka miliki. Kesehatan dikelompokkan menjadi empat macam, sehat secara jasmani, rohani, sosial dan ekonomi. Kurangnya melakukan aktivitas fisik dan olahraga akan mengakibatkan efek yang kurang baik bagi tubuh. Masyarakat Wonosari yang mempunyai kegiatan padat dapat melakukan beberapa aktivitas fisik untuk sekedar melemaskan otot maupun melancarkan peredaran darah seperti: bersepeda, jalan pagi, menyapu lantai, gotong royong di desa setiap ahad, dan lainnya. Jika memiliki waktu luang yang cukup banyak seseorang dapat melakukan olahraga. Jenis olahraga yang dapat dilakukan di lingkungan masyarakat Kelurahan Wonosari antara lain senam ritmik, sepakbola, bola voli, badminton dan jalan santai. Olahraga juga mempunyai manfaat untuk kebugaran jasmani, meraih kesehatan secara rohani, sosial dan ekonomi pada manusia.</p>

scholarly journals ATTITUDE TOWARDS HANDLING OF EMPTYPACKAGED DRINKING WATER BOTTLE

2016 ◽  
Vol 4 (9(SE)) ◽  
pp. 9-17
Author(s):  
S. Vanitha
Keyword(s):  
Drinking Water ◽  
Vital Role ◽  
The Body ◽  
Water Bottle ◽  
Environment Pollution ◽  
Industrial Growth ◽  
Green Management ◽  
Pollution Problem ◽  
The World

Water is one of most essential product for our life. Without water any living beings cannot live for a longer period of time. Water is one of the important top five sources for all. Role of water cannot be measured. Such the vital role is done by water in the body. It gives strength, clear all unnecessary contains from our body, refresh our flesh, and maintain correct temperature and so on. It is very much important that drinking a good water. These days, water is highly polluted due to the industrial growth. Therefore, water is sold in the packet. As it is little difficult to bring water wherever we go, people prefer to buy this packaged water. After drinking the water, people simply throw the packet in the dustbin. It creates the environment pollution problem. Now, green management has very important to protect the world from pollution. It urges the scholar to study about the importance of the packet water and how can be protected our environment from these waste. It also deals with giving suggestion to use packet water without pollute the environment.

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