scholarly journals The Causes of Hair Loss in Women 20-30 Years Old

2020 ◽  
Vol 5 (2) ◽  
Keyword(s):  
Vitamin D ◽  
Young Women ◽  
Hair Loss ◽  
Thyroid Function Test ◽  
Sex Hormone Binding Globulin ◽  
Full Blood Count ◽  
Care Hospital ◽  
Primary Care Level ◽  
Zinc Levels

Objective: To investigate the role of vitamins, minerals, and hormones in the pathogenesis of hair loss in young women between the ages 20 – 30 years old. Methods: We conducted a study based on young women who were referred to the Royal Wolverhampton NHS Trust, Wolverhampton (secondary care hospital) with hair loss and were investigated by requesting Full Blood Count, Serum Ferritin, B12, Folate, Zinc, Vitamin D, Thyroid Function Test, Luteinising hormone, Follicle stimulating Hormone, Testosterone, Sex hormone binding Globulin (SHBG) and Cortisol. Results: 15 out of 16 patients (93.75 %) of all the female patients who presented with alopecia were investigated and found to be deficient of Vitamin D. 16 out of 17 patients were investigated for Zinc Levels. 7 out of 17 patients (43.7%) were found to have low zinc Levels and 2 out of the 3 patients with irregular periods were noted to have low SHBG levels (66.6%) . 10 out of 16 patients (62%) were found to have abnormal ferritin levels (<20 ng/ml) and 6 out of the 17 patients (35.2%) were found to have low haemoglobin levels . Conclusion: Results from this study highlight the importance of early investigating the levels of vitamins, minerals and hormones in young women who present with alopecia and the need to conduct these blood tests as part of the routine treatment at primary care level.

scholarly journals Role of Vitamin D in Reducing the Frequency of Asthma Attacks in Patients with Frequent Exacerbation of Asthma

2021 ◽  
pp. 11-16
Author(s):  
Mubeen Ahmed Memon ◽  
Sheeba Faryal Ansari ◽  
Mumtaz Ali Lakho ◽  
Mukhtiar Hussain Jaffery ◽  
Syed Zulfiquar Ali Shah ◽  
...  
Keyword(s):  
Vitamin D ◽  
Corticosteroid Treatment ◽  
Vitamin D Supplementation ◽  
The Body ◽  
P Value ◽  
Care Hospital ◽  
Asthma Exacerbations ◽  
Vitamin D Levels ◽  
Interventional Group

Introduction: Vitamin D deficiency is common among asthmatics with literature suggesting that its low levels in the body may trigger exacerbations and decrease the response to corticosteroid treatment. It has also shown to inhibit the production of cytokines, which in turn enhances the body’s response to corticosteroid treatment during an exacerbation. Therefore, maintenance of adequate levels of vitamin D in patients with asthma may reduce the risk of exacerbation and improve their general health. This study aims to explore the role of vitamin D supplementation in preventing asthma exacerbations. Methods: This single blind parallel arm interventional study was conducted in the pulmonology ward in a tertiary care hospital from June 2018 to April 2020. Two hundred (n= 200) participants with a history of frequent acute exacerbation of asthma were enrolled in the study via consecutive convenient non-probability technique. Participants were divided into two groups; the placebo and the interventional group that received 200,000 IU of vitamin D capsule. Results: Compared to day 0, mean episodes of exacerbation in the interventional group were significantly lower after 180 days (1.1 ± 0.4 vs. 0.61 ± 0.3; p-value <0.0001). Similarly, number of asthma attacks in past 7 days was significantly lower in intervention group after 180 days (4.4 ± 2.7 vs. 3.1 ± 1.5; p-value 0.0001) Conclusion: Vitamin D supplementation is a safe and cost-friendly approach to reducing asthma exacerbations. It may also help to improve the condition in severe asthmatics with low vitamin D levels.

Role of vitamin D in hair loss: A short review

2021 ◽  
Author(s):  
Kriteeka Saini ◽  
Venkataram Mysore
Keyword(s):  
Vitamin D ◽  
Hair Loss ◽  
Short Review

Role of vitamin D and sFlt-1/PlGF ratio in the development of early- and late-onset preeclampsia

2015 ◽  
Vol 53 (7) ◽  
Author(s):  
Indira Álvarez-Fernández ◽  
Belén Prieto ◽  
Verónica Rodríguez ◽  
Yolanda Ruano ◽  
Ana I. Escudero ◽  
...  
Keyword(s):  
Vitamin D ◽  
Late Onset ◽  
Tertiary Care ◽  
Care Hospital ◽  
Hydroxyvitamin D ◽  
Increased Risk ◽  
25 Hydroxyvitamin D ◽  
The Relationship ◽  
Plgf Ratio

AbstractThe imbalanced production of placental biomarkers and vitamin D deficiency have been proposed as risk factors for the development of preeclampsia (PE). However, little is known about the relationship between them and their role in early- versus late-onset PE. The objectives were to assess the role of 25-hydroxyvitamin D [25(OH)D] concentrations and the soluble fms-like tyrosine kinase 1 (sFlt-1) to placental growth factor (PlGF) ratio in the development of early- and late-onset PE; and to evaluate the relationship between 25(OH)D and the biomarkers.A retrospective, full-blinded cohort study was conducted at the Obstetric Emergency Service of a tertiary care hospital. Pregnant women (n=257) attending obstetric triage with suspicion of PE were included. sFlt-1, PlGF and 25(OH)D concentrations were measured by electrochemoluminescence (ECLIA) immunoassay and pregnancy outcome (development of PE) was registered from patients records.PE women showed lower 25(OH)D concentrations at clinical presentation than non-PE women (median: 35.0 nmol/L and 39.6 nmol/L, respectively; p=0.027). Women with 25(OH)D levels <50 nmol/L experienced an increased risk of developing late-onset PE [odds ratio (OR) 4.6, 95% confidence interval (CI) 1.4–15], but no association was found for early-onset PE. However, a sFlt-1/PlGF ratio above the corresponding cutpoints increased the risk of developing both early- and late-onset PE [ORs 58 (95% CI 11–312) and 12 (95% CI 5.0–27), respectively]. No association was found between 25(OH)D levels and sFlt-1/PlGF ratio.Low vitamin D status in women with suspected late-onset PE increases the risk of imminent development of the disease.

TEENAGE PREGNANCY AND ITS OBSTETRICS AND NEONATAL OUTCOME IN TERTIARY CARE HOSPITAL: AN OBSERVATIONAL STUDY.

2020 ◽  
Vol 4 (6) ◽  
Author(s):  
Rashmi Kumari ◽  
Usha Kumari ◽  
Krishna Sinha
Keyword(s):  
Vitamin D ◽  
Teenage Pregnancy ◽  
Neonatal Outcome ◽  
Tertiary Care ◽  
Vitamin D Supplementation ◽  
Care Hospital ◽  
Medical College ◽  
Group I ◽  
Jawaharlal Nehru

Aim: to study the effects of teenage pregnancy on obstetrics and neonatal outcome. Materials and methods: The present prospective comparative interventional study was conducted in the Department of Obstetrics and Gynecology, Jawaharlal Nehru Medical College and Hospital, Bhagalpur, Bihar, India. Total 60 patients were divided in to two groups. Results: Majority of the patients (66.9%) were in the 18-20 years of age group. Pre-eclampsia was observed in 26.7% of the patients who didn’t receive vitamin D supplement whereas the group I which received supplementation showed on pre-eclampsia in   6.7% of the patients (p=0.001). Conclusion: This study concludes that there is significant role of vitamin D supplementation in pregnant women in prevention of pre-eclampsia. Keywords: pre-eclampsia, vitamin D, neonatal outcome, teenage

Low sex-hormone binding globulin levels in young women with diffuse hair loss

1982 ◽  
Vol 106 (3) ◽  
pp. 331-336 ◽  
Author(s):  
J.A. MILLER ◽  
C.R. DARLEY ◽  
K. KARKAVITSAS ◽  
J.D. KIRBY ◽  
D.D. MUNRO
Keyword(s):  
Young Women ◽  
Hair Loss ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding

scholarly journals Relationship Between Vitamin D Deficiency and the Amount of Sun Exposure in Young Women

2021 ◽  
Author(s):  
ŞÜKRİYE TAŞÇI KARAGÖL ◽  
sevil turhan ◽  
Hulya Coskun ◽  
Yusuf Bostan ◽  
Raziye yıldız
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Young Women ◽  
Bone Mineralization ◽  
Sunshine Duration ◽  
Sun Exposure ◽  
Care Hospital ◽  
Monthly Average ◽  
Vitamin D Levels ◽  
The Individual

Abstract Objective: Vitamin D is an essential vitamin for bone mineralization and its deficiency adversely affects many systems, predominantly the musculoskeletal system. A lack of synthesis in the skin is the key step that predominantly causes vitamin D deficiency. Vitamin D synthesis can be affected by numerous factors including geographical region of residence, seasons, monthly average daily global horizontal solar radiation (MADGHSR), monthly average daily sunshine duration (MADSD), ethnic group of the individual. The study aimed to investigate the relationship between vitamin D level and MADSD and MADGHSR values in young women. Methods: The retrospective study included women aged 15-45 years, who presented to Secondary Care Hospital for general health screening. Vitamin D levels were classified according to age groups, months, seasons, MADGHSR and MADSD values. Results: The mean vitamin D level was 17.3±7.3 ng/mL in summer and was 15.9±7.5 ng/mL in winter (p=0.001). Vitamin D deficiency (<20 ng/mL) was detected in 68.1% as opposed to 75.1% of women in summer and winter, respectively (p<0.001). A weak correlation was found between vitamin D level and age (r=0.082, p=0.002), MADGHSR (r=0.062, p=0.006), and MADSD (r=0.075, p=0.001). Conclusion: The individual and environmental factors with the MADGHSR, MADSD have a direct effect on sun exposure. The traditional and religious clothing habits of our participants constituted the most important factor contributing to their low vitamin D levels. We propose that routine vitamin D supplementation at optimal doses will be an appropriate approach in populations similar to the population studied in the present study.

scholarly journals Incidence of Vitamin D Deficiency in Patients with Female Pattern Hair Loss (FPHL)

2021 ◽  
pp. 48-53
Author(s):  
Erum Siddiqui ◽  
Shakila Yousuf ◽  
Sumbul Nisar ◽  
Faryal Hussain Memon ◽  
Anum Sharif ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Hair Loss ◽  
Vitamin D3 ◽  
Economic Status ◽  
Tertiary Care ◽  
Serum Levels ◽  
Care Hospital ◽  
Cross Sectional ◽  
Female Pattern Hair Loss

Background: Female pattern hair loss is also observed in women without increased androgen levels. Vitamin D is a factor that has recently been considered in dealing with these patients. Deficiency of Vitamin D might be correlated with diffuse hair loss. Objective: To determine the frequency of serum levels of Vitamin D3 in patients with female pattern of hair loss (FPHL) at tertiary care hospital Karachi. Methodology: This cross-sectional research was conducted upon a sample of 163 female patients (chosen via non-probability – consecutive sampling) presenting to the Dept. of Dermatology, Abbasi Shaheed Hospital, Karachi from 29th July 2018 to 28 th January 2019, with a clinical diagnosis of FPHL. Data was recorded onto a structured questionnaire containing inquiries pertaining to basic biodata, sociodemographic details, and inferences obtained from blood tests (CBC, serum ferritin, TSH level and vitamin D level). Serum 25 OH Vitamin D level < 20 was taken as deficient, 21-29 was insufficient and over 30 was sufficient. Data was analyzed using SPSS. v. 21.0. Results: The mean age was 30.39±6.36 years. Mean FPHL duration was 5.85±2.89 months. Total 63.2% patients were classified as mild, 26.45% patients were classified as moderate and 10.4% patients were classified as severe. Total 73% patients were found as vitamin D deficient, 22.1% as vitamin D insufficient and 4.9% as vitamin D sufficient. Significant association of vitamin D deficiency was observed with education status, vitamin D intake since past 6 months, and socio economic status. Conclusion: Results showed high vitamin D3 deficiency (73.0%) among patients with female pattern of hair loss (FPHL).

scholarly journals Comparative study of serum ferritin and vitamin D in thalassemia patients with healthy controls

2018 ◽  
Vol 6 (2) ◽  
pp. 693 ◽  
Author(s):  
Shweta Gombar ◽  
Kiran Parihar ◽  
Mamta Choudhary
Keyword(s):  
Vitamin D ◽  
Serum Ferritin ◽  
Genetic Disorder ◽  
Tertiary Care ◽  
P Value ◽  
Care Hospital ◽  
Globin Chains ◽  
Bony Landmarks ◽  
High Level

Background: Thalassemia is the most common genetic disorder in humans; they are encountered among all ethnic groups and in almost every country around the world. Mostly occur in the regions surrounding the Mediterranean sea, hence the name. These are a group of hereditary haemolytic disorders characterized by impairment in the synthesis of globin chains of Hb. The present study aimed to find out the serum ferritin and vitamin D level in thalassemic children in the tertiary care hospital in Bikaner, western Rajasthan, India.Methods: In this study 50 (27 male and 23 female) adult skulls were investigated to determine the type of asterion, its distance from important bony landmarks and also the nearby venous sinuses were measured.Results: Level of serum ferritin was significantly high and vitamin D was significantly low (p-value<0.0001 for both) in thalassemic children.Conclusions: In this study the role of serum ferritin and vitamin D has been explored. The extremely high level of ferritin was found due to the regular blood transfusion and consequent iron overload and low vitamin D was found due to impairment in liver functions among thalassemic children.

The role of vitamin D in metabolic and reproductive disturbances of polycystic ovary syndrome: A narrative mini-review

2020 ◽  
pp. 1-8
Author(s):  
Daniela Menichini ◽  
Gianpiero Forte ◽  
Beatrice Orrù ◽  
Giuseppe Gullo ◽  
Vittorio Unfer ◽  
...  
Keyword(s):  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Embryo Quality ◽  
Polycystic Ovary ◽  
Vitamin D Supplementation ◽  
Endometrial Receptivity ◽  
Metabolic Disturbances ◽  
Ovary Syndrome ◽  
Beneficial Role

Abstract. Vitamin D is a secosteroid hormone that plays a pivotal role in several metabolic and reproductive pathways in humans. Increasing evidence supports the role of vitamin D deficiency in metabolic disturbances and infertility in women with polycystic ovary syndrome (PCOS). Indeed, supplementation with vitamin D seems to have a beneficial role on insulin resistance and endometrial receptivity. On the other hand, exceedingly high levels of vitamin D appear to play a detrimental role on oocytes development and embryo quality. In the current review, we summarize the available evidence about the topic, aiming to suggest the best supplementation strategy in women with PCOS or, more generally, in those with metabolic disturbances and infertility. Based on the retrieved data, vitamin D seems to have a beneficial role on IR, insulin sensitivity and endometrial receptivity, but high levels and incorrect timing of administration seem to have a detrimental role on oocytes development and embryo quality. Therefore, we encourage a low dose supplementation (400–800 IU/day) particularly in vitamin D deficient women that present metabolic disturbances like PCOS. As far as the reproductive health, we advise vitamin D supplementation in selected populations, only during specific moments of the ovarian cycle, to support the luteal phase. However, ambiguities about dosage and timing of the supplementation still emerge from the clinical studies published to date and further studies are required.

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