scholarly journals The role of specialist nurses in multiple sclerosis: a rapid and systematic review

2001 ◽  
Vol 5 (17) ◽  
Author(s):  
S. De Broe ◽  
F. Christopher ◽  
N. Waugh
Keyword(s):  
Multiple Sclerosis ◽  
Systematic Review ◽  
Specialist Nurses

Efficacy of probiotics in multiple sclerosis: a systematic review of preclinical trials and meta-analysis of randomized controlled trials

2021 ◽  
Author(s):  
Jinchi Jiang ◽  
Chuanqi Chu ◽  
Caie Wu ◽  
Chen Wang ◽  
Chengcheng Zhang ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Potential Role ◽  
Meta Analysis ◽  
Preliminary Evidence ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Preclinical Trials

Preliminary evidence shows the potential role of probiotics in ameliorating multiple sclerosis (MS); however, the effects of probiotics on MS remain unclear.

scholarly journals The role of expectations and future-oriented cognitions in quality of life of people with multiple sclerosis: A systematic review

2021 ◽  
pp. 103293
Author(s):  
Rebecca Maguire ◽  
Beth McKeague ◽  
Nathalie Kóka ◽  
Laura Coffey ◽  
Phil Maguire ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Systematic Review

A Systematic Review on the Role of Arachidonic Acid Pathway in Multiple Sclerosis

2020 ◽  
Vol 19 ◽  
Author(s):  
Malvina Hoxha ◽  
Erila Spahiu ◽  
Emanuela Prendi ◽  
Bruno Zappacosta
Keyword(s):  
Multiple Sclerosis ◽  
Systematic Review ◽  
Arachidonic Acid ◽  
Immune Cell ◽  
Inflammatory Responses ◽  
Lox Inhibitors ◽  
Acid Pathway ◽  
Arachidonic Acid Pathway

Background & Objective: Multiple sclerosis (MS) is an inflammatory neurodegenerative disease characterized by destruction of oligodendrocytes, immune cell infiltration and demyelination. Inflammation plays a significant role in MS, and the inflammatory mediators such as eicosanoids, leukotrienes, superoxide radicals are involved in pro-inflammatory responses in MS. In this systematic review we tried to define and discuss all the findings of in vivo animal studies and human clinical trials on the potential association between arachidonic acid (AA) pathway and multiple sclerosis. Methods: A systematic literature search across Pubmed, Scopus, Embase and Cochrane database was conducted. This systematic review was performed according to PRISMA guidelines. Results: A total of 146 studies were included, of which 34 were conducted in animals, 58 in humans, and 60 studies reported the role of different compounds that target AA mediators or their corresponding enzymes/ receptors, and can have a therapeutic effect in MS. These results suggest that eicosanoids have significant roles in experimental autoimmune encephalomyelitis (EAE) and MS. The data from animal and human studies elucidated that PGI2, PGF2α, PGD2, isoprostanes, PGE2, PLA2, LTs are increased in MS. PLA2 inhibition modulates the progression of the disease. PGE1 analogues can be a useful option in the treatment of MS. Conclusions: All studies reported the beneficial effects of COX and LOX inhibitors in MS. The hybrid compounds, such as COX-2 inhibitors/TP antagonists and 5-LOX inhibitors can be an innovative approach for multiple sclerosis treatment. Future work in MS should shed light in synthesizing new compounds targeting arachidonic acid pathway.

The role of gluten in multiple sclerosis: A systematic review

2019 ◽  
Vol 27 ◽  
pp. 156-163 ◽  
Author(s):  
Henriette Lynge Thomsen ◽  
Elise Barsøe Jessen ◽  
Moschoula Passali ◽  
Jette Lautrup Frederiksen
Keyword(s):  
Multiple Sclerosis ◽  
Systematic Review

scholarly journals Role of disease-modifying oral drugs in multiple sclerosis: A systematic review with meta-analysis

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Minerva López-Ruiz ◽  
Silvia Guzmán-Vázquez ◽  
Osvaldo Díaz-Álvarez ◽  
Yareli O. Buendía-López ◽  
Herman Soto-Molina
Keyword(s):  
Multiple Sclerosis ◽  
Systematic Review ◽  
Meta Analysis ◽  
Oral Drugs ◽  
Disease Modifying

The role of phospholipase A2 in multiple Sclerosis: A systematic review and meta-analysis

2019 ◽  
Vol 27 ◽  
pp. 206-213 ◽  
Author(s):  
Austin Trotter ◽  
Emily Anstadt ◽  
Robert B. Clark ◽  
Frank Nichols ◽  
Alok Dwivedi ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Systematic Review ◽  
Phospholipase A2 ◽  
Meta Analysis
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