scholarly journals Neuroleptics in the treatment of aggressive challenging behaviour for people with intellectual disabilities: a randomised controlled trial (NACHBID)

2009 ◽  
Vol 13 (21) ◽  
Author(s):  
P Tyrer ◽  
P Oliver-Africano ◽  
R Romeo ◽  
M Knapp ◽  
S Dickens ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Intellectual Disabilities ◽  
Controlled Trial ◽  
Challenging Behaviour ◽  
People With Intellectual Disabilities ◽  
Randomised Controlled

scholarly journals Adults with untreated phenylketonuria: out of sight, out of mind

2008 ◽  
Vol 193 (6) ◽  
pp. 501-502 ◽  
Author(s):  
Glynis H. Murphy ◽  
Sally M. Johnson ◽  
Allayne Amos ◽  
Eleanor Weetch ◽  
Rosemary Hoskin ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Controlled Trial ◽  
Support Needs ◽  
Challenging Behaviour ◽  
Restricted Diet ◽  
Randomised Controlled ◽  
High Support

SummarySome people with phenylketonuria who were born before screening began were never treated and are still alive. Here we report that far fewer people with untreated phenylketonuria were detected than are thought to exist (about 2000). The majority of those traced had high support needs, challenging behaviour and other symptoms of phenylketonuria. No significant differences were found between those who had or had not tried the phenylalanine-restricted diet. A randomised controlled trial is required to examine the effect of trying the low-phenylalanine diet for people with untreated phenylketonuria.

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