scholarly journals Topical or oral ibuprofen for chronic knee pain in older people. The TOIB study

2008 ◽  
Vol 12 (22) ◽  
Author(s):  
M Underwood ◽  
D Ashby ◽  
D Carnes ◽  
E Castelnuovo ◽  
P Cross ◽  
...  
Keyword(s):  
Older People ◽  
Knee Pain ◽  
Chronic Knee Pain ◽  
Oral Ibuprofen

scholarly journals Advice to use topical or oral ibuprofen for chronic knee pain in older people: randomised controlled trial and patient preference study

BMJ ◽  
2007 ◽  
Vol 336 (7636) ◽  
pp. 138-142 ◽  
Author(s):  
Martin Underwood ◽  
Deborah Ashby ◽  
Pamela Cross ◽  
Enid Hennessy ◽  
Louise Letley ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Older People ◽  
Knee Pain ◽  
Patient Preference ◽  
Controlled Trial ◽  
Chronic Knee Pain ◽  
Oral Ibuprofen ◽  
Randomised Controlled ◽  
Preference Study

scholarly journals Oral Versus Topical Ibuprofen for Chronic Knee Pain: A Prospective Randomized Pilot Study

2010 ◽  
Vol 5;13 (5;9) ◽  
pp. 457-467
Author(s):  
Sarani Tong-Ngork
Keyword(s):  
Patient Satisfaction ◽  
Pilot Study ◽  
Physical Function ◽  
Knee Pain ◽  
Pain Treatment ◽  
Short Form ◽  
Topical Gel ◽  
Chronic Knee Pain ◽  
Oral Ibuprofen ◽  
Mean Differences

Background: Topical ibuprofen provides an alternative treatment to oral ibuprofen for the treatment of chronic knee pain. Objective: To compare the efficacy of topical versus oral ibuprofen in chronic knee pain treatment. Study Design: Prospective, randomized, unblinded pilot study. Setting: A private pain management practice. Methods: Twenty patients received either ibuprofen tablets 3 times daily (2400 mg total) or 4% topical gel 4 times daily (320 mg total) for 2 weeks. Subjects completed the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index, the Medical Outcomes Study 12-Item Short Form (SF-12v2) Health Survey, and a satisfaction questionnaire. Results: Comparison of WOMAC and SF-12v2 mean changes from baseline showed no differences between groups. Patient satisfaction and study treatment convenience were rated equivalently between groups. Within the topical group, significant improvements (P < 0.05) were experienced in the mean differences of WOMAC Pain scores from baseline to 2 weeks (-82.6, -158.3 to -6.8), WOMAC Stiffness scores from baseline to one week (-25.3, -50.0 to -0.6) and baseline to 2 weeks (-47.8, -95.7 to 0.1), WOMAC Physical Function scores from baseline to one week (-175.9, -348.6 to -3.2) and baseline to 2 weeks (-312.1, -580.5 to -43.7), and patient satisfaction scores from baseline to one week and baseline to 2 weeks. Within the oral group, significant improvements (P < 0.05) were experienced in mean differences of WOMAC Physical Function from baseline to one week (-342.6, -638.1 to -47.1) and baseline to 2 weeks (-323.2, -637.1 to -9.2). Limitations: As this was a preliminary investigation, the sample size of 20 subjects is a limitation in this study. Conclusion: Treatment of chronic knee pain with topical ibuprofen provided comparable clinical efficacy and patient satisfaction as oral ibuprofen in this pilot study. Key words: Topical ibuprofen, knee osteoarthritis, chronic pain

scholarly journals 75. How do GPs Explain Chronic Knee Pain in Older Adults? Preliminary Results from a National Pilot GP Questionnaire Survey

Rheumatology ◽  
2014 ◽  
Vol 53 (suppl_1) ◽  
pp. i83-i83
Author(s):  
Elizabeth Cottrell ◽  
Elaine Thomas ◽  
Trishna Rathod ◽  
Edward Roddy ◽  
Mark Porcheret ◽  
...  
Keyword(s):  
Older Adults ◽  
Knee Pain ◽  
Questionnaire Survey ◽  
Preliminary Results ◽  
Chronic Knee Pain
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