The Effect of Aqueous Extract of Capparis spinosa Flowers on the Level of Serum Lipids in Rabbits

2012 ◽  
Vol 10 (2) ◽  
Author(s):  
Vellingiri Vadivel ◽  
Sambasivam Manikandaselvi ◽  
Pemaiah Brindha

Capparis spinosa L. (Capparaceae) is growing wild on walls or in rocky coastal areas all over India and normally known as Maratimokku in Tamil. The current study was aimed reveal the botanical and chemical pharmacognostic standards, and pharmacological and toxicity properties of aqueous extract of C. spinosa flower buds. Powder microscopy revealed the characteristics features of the sample, which are useful in fixing the pharmacognostic standards. Preliminary phytochemical screening revealed the presence of alkaloids, reducing sugars, carbohydrates, saponins, phenolic compounds, tannins, anthraquinones and lignins in aqueous extract. LC-MS/MS analysis revealed the presence of quercetin as the major constituent in the aqueous extract. Strong antioxidant activity was observed in aqueous extract centered on the outcomes of DPPH radical scavenging (IC-50 1.74 µg/ml) and inhibition of lipid peroxidation (IC-50 4.01 µg/ml) assays. The aqueous extract exhibited anti-inflammatory activity in terms of inhibition of protein denaturation (IC-50 8.01 µg/ml), inhibition of protease activity (14.24%) and RBC membrane stabilization (IC-50 226.69 µg/ml) and also possess antibacterial activity against Bacillus cereus, Staphylococcus aureus, Campylobacter jejuni and Salmonella enteritidis strains. Acute oral toxicity study revealed that it is safe up to the dose level of 2000 mg/kg bw in the experimental animals.


2010 ◽  
Vol 58 (24) ◽  
pp. 12717-12721 ◽  
Author(s):  
Haifeng Zhou ◽  
Renji Jian ◽  
Jie Kang ◽  
Xiaoling Huang ◽  
Yan Li ◽  
...  

2019 ◽  
Vol 25 (105) ◽  
pp. 140-149
Author(s):  
Fakhri S. Alajeeli Ph.D ,A.M.TAHA ,M.SC,

Objective: DMT 2 is the common metabolic disorders with highly  impact on quality of life.  The tsability of C. Spinosa fruits extract in reducing plasma glucose levels and serum lipids was tested . There is no study  about the anti-diabetic , anti- obesity effect of  capparis spinosa  fruits in Iraq  . Therefore, we aim to study the effects of the C. spinosa fruits on diabetic obese patients.


2021 ◽  
pp. 3350-3357
Author(s):  
Rabah Hassan Saady ◽  
Abdulrahman Jihad Mansoor

       The results of the present study show the biological effects of ethyl elcoholic and aquatic extracts as well as alkaloids compounds  of Atriplex helmius and Capparis spinosa  roots. The results demonstrated the superiority of the cold aqueous extract of C. capparis at the highest concentration of 20 mg / ml, as the killing rate was 81.16% for the second  larval instar of Cx. pipiens after 72 hours of exposure. While, the killing rate caused by the same treatment was 79.52% for the third larval instar. The results also showed the superiority of the alcoholic extract against C.  spinosa , as the killing rate reached 98.55% for the second larval instar after 72 hours of treatment at a concentration of 20 mg/ml. As for A. halmius extract, the same treatment caused the lowest killing rate of 89.27% ​​ for the third instar of Cx. pipiens. The study also showed significant effects of the raw alkaline compounds’ extracts of A. halimus  roots on the killing of non-adult instars of Cx. pipiens L. The highest rate of mortality observed was 88.54% at the highest concentration of 20 mg /ml at the second instar. Also, significant effects of raw alkaline compounds’ extracts of C. spinosa roots were observed. The highest mortality was 69.21% at the highest concentration of 20 mg/ml for the third larval instar,                                                         


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