scholarly journals Synthesis of bio-functionalized three-dimensional titania nanofibrous 3 using femtosecond laser ablation

2021 ◽  
Author(s):  
Amirhossein Tavangar ◽  
Bo Tan ◽  
Krishnan Venkatakrishnan
Keyword(s):  
Femtosecond Laser ◽  
Three Dimensional ◽  
Titanium Substrate ◽  
Chemical Properties ◽  
Femtosecond Laser Ablation ◽  
Cell Interaction ◽  
Primary Objective ◽  
Femtosecond Laser Irradiation ◽  
Ambient Conditions

The primary objective of current tissue regeneration research is to synthesize nano-based platforms that 24 can induce guided, controlled, and rapid healing. Titanium nanotubes have been extensively considered 25 as a new biomaterial for biosensors, implants, cell growth, tissue engineering, and drug delivery systems. 26 However, cell adhesion to nanotubes is poor due to their chemical inertness, as well as the one-dimen- 27 sional structure, and surface modification is required to enhance nanotube–cell interaction. While there 28 have been a considerable number of studies on growing titanium nanotubes, synthesizing a three-dimen- 29 sional (3-D) nano-architecture which can act as a growth support platform for bone and stem cells has 30 not been reported so far. Therefore, we present a novel technique to synthesize and grow 3-D titania 31 interwoven nanofibrous structures on a titanium substrate using femtosecond laser irradiation under 32 ambient conditions. This surface architecture incorporate the functions of 3-D nano-scaled topography 33 and modified chemical properties to improve osseointegration while at the same time leaving space to 34 deliver other functional agents. The results indicate that laser pulse repetition can control the density 35 and pore size of engineered nanofibrous structures. In vitro experiments reveal that the titania nanofi- 36 brous architecture possesses excellent bioactivity and can induce rapid, uniform, and controllable 37 bone-like apatite precipitation once immersed in simulated body fluid (SBF). This approach to synthesiz- 38 ing 3-D titania nanofibrous structures suggests considerable promise for the promotion of Ti interfacial 39 properties to develop new functional biomaterials for various biomedical applications.

scholarly journals Synthesis of bio-functionalized three-dimensional titania nanofibrous 3 using femtosecond laser ablation

2021 ◽  
Author(s):  
Amirhossein Tavangar ◽  
Bo Tan ◽  
Krishnan Venkatakrishnan
Keyword(s):  
Femtosecond Laser ◽  
Three Dimensional ◽  
Titanium Substrate ◽  
Chemical Properties ◽  
Femtosecond Laser Ablation ◽  
Cell Interaction ◽  
Primary Objective ◽  
Femtosecond Laser Irradiation ◽  
Ambient Conditions

The primary objective of current tissue regeneration research is to synthesize nano-based platforms that 24 can induce guided, controlled, and rapid healing. Titanium nanotubes have been extensively considered 25 as a new biomaterial for biosensors, implants, cell growth, tissue engineering, and drug delivery systems. 26 However, cell adhesion to nanotubes is poor due to their chemical inertness, as well as the one-dimen- 27 sional structure, and surface modification is required to enhance nanotube–cell interaction. While there 28 have been a considerable number of studies on growing titanium nanotubes, synthesizing a three-dimen- 29 sional (3-D) nano-architecture which can act as a growth support platform for bone and stem cells has 30 not been reported so far. Therefore, we present a novel technique to synthesize and grow 3-D titania 31 interwoven nanofibrous structures on a titanium substrate using femtosecond laser irradiation under 32 ambient conditions. This surface architecture incorporate the functions of 3-D nano-scaled topography 33 and modified chemical properties to improve osseointegration while at the same time leaving space to 34 deliver other functional agents. The results indicate that laser pulse repetition can control the density 35 and pore size of engineered nanofibrous structures. In vitro experiments reveal that the titania nanofi- 36 brous architecture possesses excellent bioactivity and can induce rapid, uniform, and controllable 37 bone-like apatite precipitation once immersed in simulated body fluid (SBF). This approach to synthesiz- 38 ing 3-D titania nanofibrous structures suggests considerable promise for the promotion of Ti interfacial 39 properties to develop new functional biomaterials for various biomedical applications.

scholarly journals Synthesis of three-dimensional calcium carbonate nanofibrous structure from eggshell using femtosecond laser ablation

2021 ◽  
Author(s):  
Amirhossein Tavangar ◽  
Bo Tan ◽  
Krishnan Venkatakrishnan
Keyword(s):  
Calcium Carbonate ◽  
Femtosecond Laser ◽  
Three Dimensional ◽  
Femtosecond Laser Ablation ◽  
Bone Substitutes ◽  
Cell Interaction ◽  
Single Step ◽  
Femtosecond Laser Irradiation ◽  
Ambient Conditions ◽  
Functional Biomaterials

Background Natural biomaterials from bone-like minerals derived from avian eggshells have been considered as promising bone substitutes owing to their biodegradability, abundance, and lower price in comparison with synthetic biomaterials. However, cell adhesion to bulk biomaterials is poor and surface modifications are required to improve biomaterial-cell interaction. Three-dimensional (3D) nanostructures are preferred to act as growth support platforms for bone and stem cells. Although there have been several studies on generating nanoparticles from eggshells, no research has been reported on synthesizing 3D nanofibrous structures. Results In this study, we propose a novel technique to synthesize 3D calcium carbonate interwoven nanofibrous platforms from eggshells using high repetition femtosecond laser irradiation. The eggshell waste is value engineered to calcium carbonate nanofibrous layer in a single step under ambient conditions. Our striking results demonstrate that by controlling the laser pulse repetition, nanostructures with different nanofiber density can be achieved. This approach presents an important step towards synthesizing 3D interwoven nanofibrous platforms from natural biomaterials. Conclusion The synthesized 3D nanofibrous structures can promote biomaterial interfacial properties to improve cell-platform surface interaction and develop new functional biomaterials for a variety of biomedical applications.

scholarly journals Synthesis of three-dimensional calcium carbonate nanofibrous structure from eggshell using femtosecond laser ablation

2021 ◽  
Author(s):  
Amirhossein Tavangar ◽  
Bo Tan ◽  
Krishnan Venkatakrishnan
Keyword(s):  
Calcium Carbonate ◽  
Femtosecond Laser ◽  
Three Dimensional ◽  
Femtosecond Laser Ablation ◽  
Bone Substitutes ◽  
Cell Interaction ◽  
Single Step ◽  
Femtosecond Laser Irradiation ◽  
Ambient Conditions ◽  
Functional Biomaterials

Background Natural biomaterials from bone-like minerals derived from avian eggshells have been considered as promising bone substitutes owing to their biodegradability, abundance, and lower price in comparison with synthetic biomaterials. However, cell adhesion to bulk biomaterials is poor and surface modifications are required to improve biomaterial-cell interaction. Three-dimensional (3D) nanostructures are preferred to act as growth support platforms for bone and stem cells. Although there have been several studies on generating nanoparticles from eggshells, no research has been reported on synthesizing 3D nanofibrous structures. Results In this study, we propose a novel technique to synthesize 3D calcium carbonate interwoven nanofibrous platforms from eggshells using high repetition femtosecond laser irradiation. The eggshell waste is value engineered to calcium carbonate nanofibrous layer in a single step under ambient conditions. Our striking results demonstrate that by controlling the laser pulse repetition, nanostructures with different nanofiber density can be achieved. This approach presents an important step towards synthesizing 3D interwoven nanofibrous platforms from natural biomaterials. Conclusion The synthesized 3D nanofibrous structures can promote biomaterial interfacial properties to improve cell-platform surface interaction and develop new functional biomaterials for a variety of biomedical applications.

scholarly journals Synthesis of Nanotips Through Femtosecond Laser Ablation of Glass with Assisted Gas

2021 ◽  
Author(s):  
Nikunj Patel
Keyword(s):  
Femtosecond Laser ◽  
Building Materials ◽  
High Vacuum ◽  
Synthesis Method ◽  
Femtosecond Laser Ablation ◽  
Target Surface ◽  
Laser Pulses ◽  
Single Step ◽  
Femtosecond Laser Irradiation ◽  
Ambient Conditions

Nanotips are the key nanostructures for many applications. Until now, the nanotips of only the crystalline materials have been produced via various deposition methods which require sophisticated equipment, high vacuum, and clean room operations. This thesis proposes a single step, rapid synthesis method using femtosecond laser irradiation at megahertz frequency with background flow of nitrogen gas at ambient conditions. Amorphous nanotips are obtained without the use of catalyst. The nanotips grow from highly energetic plasma generated when target is irradiated with laser pulses. The vapor condensates, nanoparticles and droplets from the plasma get deposited back on to the hot target surface where they experience force imbalance due to which the stems for the nanotips growth are initiated. Once the stems are generated, the continuous deposition of vapor condensates [sic] provides building materials to the stems to complete the growth of nanotips. Further study found that the growth of the nanotips is influenced by laser parameters and gas conditions.

scholarly journals Experimental Investigation Of Nanostructures Generated On Glasses Using A MHz Femtosecond Laser

2021 ◽  
Author(s):  
Dheeraj Vipparty
Keyword(s):  
Femtosecond Laser ◽  
Laser Irradiation ◽  
Dwell Time ◽  
Three Dimensional ◽  
Soda Lime ◽  
Femtosecond Laser Irradiation ◽  
Soda Lime Glass ◽  
Ambient Conditions ◽  
Nanoparticle Agglomerate ◽  
Insight Into

This dissertation reports the synthesis of unique Si0₂ based nanostructures by exposing glass samples to MHz repletion rate femtosecond laser irradiation. A three-dimensional fibrous nanoparticle agglomerate network was observed on soda-lime glass (73% SiO + other compounds) when exposed to femtosecond laser irradiation at 8.4 MHz and 12.6 MHz repetition rate and 0.5 ms dwell time, in air. By irradiating silica glass (96% SiO₂+ trace elements) sample under ambient conditions with femtosecond pulses at 12.6 MHz and dwell time in excess of 3.0 ms; long continuous nanofibers of extremely high aspect ration (certain fibers up to 100000:1) were obtained. The mechanisms that promote such nanostructures with distinct morphologies have been explored. A deeper insight into the fundamentals of femtosecond laser interaction with dielectrics led to the understanding that variations in bandgap alters ablation dynamics and dictates the response of glass to femtosecond laser irradiation, ultimately resulting in the formation of structures with dissimilar morphology on silica and soda-lime glass.

scholarly journals Experimental Investigation Of Nanostructures Generated On Glasses Using A MHz Femtosecond Laser

2021 ◽  
Author(s):  
Dheeraj Vipparty
Keyword(s):  
Femtosecond Laser ◽  
Laser Irradiation ◽  
Dwell Time ◽  
Three Dimensional ◽  
Soda Lime ◽  
Femtosecond Laser Irradiation ◽  
Soda Lime Glass ◽  
Ambient Conditions ◽  
Nanoparticle Agglomerate ◽  
Insight Into

This dissertation reports the synthesis of unique Si0₂ based nanostructures by exposing glass samples to MHz repletion rate femtosecond laser irradiation. A three-dimensional fibrous nanoparticle agglomerate network was observed on soda-lime glass (73% SiO + other compounds) when exposed to femtosecond laser irradiation at 8.4 MHz and 12.6 MHz repetition rate and 0.5 ms dwell time, in air. By irradiating silica glass (96% SiO₂+ trace elements) sample under ambient conditions with femtosecond pulses at 12.6 MHz and dwell time in excess of 3.0 ms; long continuous nanofibers of extremely high aspect ration (certain fibers up to 100000:1) were obtained. The mechanisms that promote such nanostructures with distinct morphologies have been explored. A deeper insight into the fundamentals of femtosecond laser interaction with dielectrics led to the understanding that variations in bandgap alters ablation dynamics and dictates the response of glass to femtosecond laser irradiation, ultimately resulting in the formation of structures with dissimilar morphology on silica and soda-lime glass.

scholarly journals Synthesis of Nanotips Through Femtosecond Laser Ablation of Glass with Assisted Gas

2021 ◽  
Author(s):  
Nikunj Patel
Keyword(s):  
Femtosecond Laser ◽  
Building Materials ◽  
High Vacuum ◽  
Synthesis Method ◽  
Femtosecond Laser Ablation ◽  
Target Surface ◽  
Laser Pulses ◽  
Single Step ◽  
Femtosecond Laser Irradiation ◽  
Ambient Conditions

Nanotips are the key nanostructures for many applications. Until now, the nanotips of only the crystalline materials have been produced via various deposition methods which require sophisticated equipment, high vacuum, and clean room operations. This thesis proposes a single step, rapid synthesis method using femtosecond laser irradiation at megahertz frequency with background flow of nitrogen gas at ambient conditions. Amorphous nanotips are obtained without the use of catalyst. The nanotips grow from highly energetic plasma generated when target is irradiated with laser pulses. The vapor condensates, nanoparticles and droplets from the plasma get deposited back on to the hot target surface where they experience force imbalance due to which the stems for the nanotips growth are initiated. Once the stems are generated, the continuous deposition of vapor condensates [sic] provides building materials to the stems to complete the growth of nanotips. Further study found that the growth of the nanotips is influenced by laser parameters and gas conditions.

scholarly journals Evidence of diffusive fractal aggregation of TiO2 nanoparticles by femtosecond laser ablation at ambient conditions

2017 ◽  
Vol 4 (1) ◽  
pp. 015013 ◽  
Author(s):  
G L Celardo ◽  
D Archetti ◽  
G Ferrini ◽  
L Gavioli ◽  
P Pingue ◽  
...  
Keyword(s):  
Laser Ablation ◽  
Femtosecond Laser ◽  
Tio2 Nanoparticles ◽  
Femtosecond Laser Ablation ◽  
Ambient Conditions

Molecular Dynamics Study of Mechanism of Ablation Induced by a Femtosecond Laser Pulse

2003 ◽  
Author(s):  
Changrui Cheng ◽  
Xianfan Xu
Keyword(s):  
Molecular Dynamics ◽  
Laser Ablation ◽  
Laser Pulse ◽  
Femtosecond Laser ◽  
Critical Point ◽  
Change Process ◽  
Femtosecond Laser Ablation ◽  
Md Simulations ◽  
Femtosecond Laser Irradiation ◽  
Transient Temperature

In this work, molecular dynamics (MD) simulations are carried out to study femtosecond laser ablation of a metal, with an emphasis on the understanding of the mechanism of laser ablation. Theoretically, it has been shown that under intense femtosecond laser irradiation, the material can undergo a volumetric phase change process; its temperature can be close to or even above the critical point. MD simulations allow us to determine the transient temperature of the irradiated material as well as the transient thermodynamic state, which explain the mechanisms of femtosecond laser ablation.

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