scholarly journals Heart Disease Prediction Based on Optimized Random Forest Model Using Machine Learning

Author(s):  
Prof. R. A. Jamadar ◽  
Aarati Garje ◽  
Tejasvi Bhorde ◽  
Vaishnavi Jadhav

Heart disease is one amongst the key causes of death now-a-days. Prediction of the center sickness is troublesome, time overwhelming and expensive, therefore we tend to try to beat it. This analysis is to assist individuals, as we all know prediction of upset may be a vital challenge and it’s expensive that most of the individuals can’t afford and lacking behind due to these, therefore to assist them for obtaining done this tests in low value, we tend to try to develop cardiovascular disease prediction system victimization machine learning. As there square measure several systems designed for machine-controlled coronary failure testing however it's some drawbacks like over fitting that we tend to try to beat in our system and implementing system which is able to show smart performance and have high accuracy as compared to alternative systems. Experiment is performed victimization on-line clinical coronary failure dataset. The projected methodology is a smaller amount complicated with high accuracy of report. They contributes towards study square measure as follows: one. AN intelligent learning system RSA-RF is projected for the machine-controlled detection of coronary failure. The projected RSA-RF model was projected and developed for the primary time for the center failure detection. Previously, RSA algorithms have shown winning applications in looking best hyper parameters of a model. This paper presents its application in looking best set of options. 2. The developed learning system improves coronary failure prediction of typical random forest model by three.3% and shows higher performance than eleven recently projected strategies and alternative state of the art machine learning models for coronary failure detection. Moreover, the projected methodology shows lower time complexness because it reduces the amount of options[1].

2021 ◽  
Author(s):  
Jaishri Pandhari Wankhede ◽  
Palaniappan S ◽  
Magesh Kumar S

The objective of the paper is to throw light on few existing heart disease predicting approaches and proposes a Hybrid Random Forest Model Integrated with Linear Model (HRFMILM) for predicting and identifying the HDs at an early stage. Even though the linear model has simple estimation procedure, it is very sensitive to outliers and may lead to overfitting process. On the other hand, averaging in Random Forest Model (RFM) improves the overall accuracy and reduces the possibility of overfitting. The dataset is collected from standard UCI repository. Experimental results concluded that the integration of Linear Model with RFM makes the simple estimation procedure with improved overall accuracy than the respective models. Further, the proposed method compares the prediction performance of few existing approaches in terms of parameters, namely, precision, recall and F1-score.


Author(s):  
Ramesh Ponnala ◽  
K. Sai Sowjanya

Prediction of Cardiovascular ailment is an important task inside the vicinity of clinical facts evaluation. Machine learning knowledge of has been proven to be effective in helping in making selections and predicting from the huge amount of facts produced by using the healthcare enterprise. on this paper, we advocate a unique technique that pursuits via finding good sized functions by means of applying ML strategies ensuing in improving the accuracy inside the prediction of heart ailment. The severity of the heart disease is classified primarily based on diverse methods like KNN, choice timber and so on. The prediction version is added with special combos of capabilities and several known classification techniques. We produce a stronger performance level with an accuracy level of a 100% through the prediction version for heart ailment with the Hybrid Random forest area with a linear model (HRFLM).


2019 ◽  
Author(s):  
Manesh Chawla ◽  
Amreek Singh

Abstract. Fast downslope release of snow (avalanche) is a serious hazard to people living in snow bound mountains. Released snow mass can gain sufficient momentum on its down slope path to kill humans, uproot trees and rocks, destroy buildings. Direct reduction of avalanche threat is done by building control structures to add mechanical support to snowpack and reduce or deflect downward avalanche flow. On large terrains it is economically infeasible to use these methods on each high risk site.Therefore predicting and avoiding avalanches is the only feasible method to reduce threat but sufficient snow stability data for accurate forecasting is generally unavailable and difficult to collect. Forecasters infer snow stability from their knowledge of local weather, terrain and sparsely available snowpack observations. This inference process is vulnerable to human bias therefore machine learning models are used to find patterns from past data and generate helpful outputs to minimise and quantify uncertainty in forecasting process. These machine learning techniques require long past records of avalanches which are difficult to obtain. In this paper we propose a data efficient Random Forest model to address this problem. The model can generate a descriptive forecast showing reasoning and patterns which are difficult to observe manually. Our model advances the field by being inexpensive and convenient for operational forecasting due to its data efficiency, ease of automation and ability to describe its decisions.


Cancers ◽  
2021 ◽  
Vol 13 (23) ◽  
pp. 6013
Author(s):  
Hyun-Soo Park ◽  
Kwang-sig Lee ◽  
Bo-Kyoung Seo ◽  
Eun-Sil Kim ◽  
Kyu-Ran Cho ◽  
...  

This prospective study enrolled 147 women with invasive breast cancer who underwent low-dose breast CT (80 kVp, 25 mAs, 1.01–1.38 mSv) before treatment. From each tumor, we extracted eight perfusion parameters using the maximum slope algorithm and 36 texture parameters using the filtered histogram technique. Relationships between CT parameters and histological factors were analyzed using five machine learning algorithms. Performance was compared using the area under the receiver-operating characteristic curve (AUC) with the DeLong test. The AUCs of the machine learning models increased when using both features instead of the perfusion or texture features alone. The random forest model that integrated texture and perfusion features was the best model for prediction (AUC = 0.76). In the integrated random forest model, the AUCs for predicting human epidermal growth factor receptor 2 positivity, estrogen receptor positivity, progesterone receptor positivity, ki67 positivity, high tumor grade, and molecular subtype were 0.86, 0.76, 0.69, 0.65, 0.75, and 0.79, respectively. Entropy of pre- and postcontrast images and perfusion, time to peak, and peak enhancement intensity of hot spots are the five most important CT parameters for prediction. In conclusion, machine learning using texture and perfusion characteristics of breast cancer with low-dose CT has potential value for predicting prognostic factors and risk stratification in breast cancer patients.


Author(s):  
Qian Zhao ◽  
Ning Xu ◽  
Hui Guo ◽  
Jianguo Li

Background: Sepsis is a life-threatening disease caused by the dysregulated host response to the infection, and being the major cause of death to patients in intensive care unit (ICU). Objective: Early diagnosis of sepsis could significantly reduce in-hospital mortality. Though generated from infection, the development of sepsis follows its own psychological process and disciplines, alters with gender, health status and other factors. Hence, the analysis of mass data by bioinformatic tools and machine learning is a promising method for exploring early diagnosis manners. Method: We collected miRNA and mRNA expression data of sepsis blood samples from Gene Expression Omnibus (GEO) and ArrayExpress databases, screened out differentially expressed genes (DEGs) by R software, predicted miRNA targets on TargetScanHuman and miRTarBase websites, conducted Gene Ontology (GO) term and KEGG pathway enrichment based on overlapping DEGs. The STRING database and Cytoscape were used to build protein-protein interaction (PPI) network and predict hub genes. Then we constructed a Random Forest model by using the hub genes to assess sample type. Results: Bioinformatic analysis of GEO dataset revealed 46 overlapping DEGs in sepsis. The PPI network analysis identified five hub genes, SOCS3, KBTBD6, FBXL5, FEM1C and WSB1. Random Forest model based on these five hub genes was used to assess GSE95233 and GSE95233 datasets, and the area under curve (AUC) of ROC are 0.900 and 0.7988, respectively, which confirmed the efficacy of this model. Conclusion: The integrated analysis of gene expression in sepsis and the effective Random Forest model built in this study may provide promising diagnostic methods for sepsis.


Author(s):  
Usman Ahmed ◽  
Matthew J. Roorda

The choice of vehicle type is one of the important logistics decisions made by firms. The complex nature of the choice process is because of the involvement of multiple agents. This study employs a random forest machine learning algorithm to represent these complex interactions with limited information about shipment transportation. The data are from Commercial Travel Surveys with information about outbound shipment transportation. This study models the choice among four road transport vehicle types: pickup/cube van, single-unit truck, tractor trailer, and passenger car. The characteristics of firms and shipments are used as explanatory variables. SHAP-based variable importance is calculated to interpret the importance of each variable, and shows that employment and weight are the most important variables in determining the choice of vehicle type. The random forest model is also compared with the multinomial and mixed logit models. The model prediction results on the validation data are compared. The results show that random forest model outperforms both the multinomial and mixed logit model with an overall increase in accuracy of about 7.8% and 9.6%, respectively.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Eun Kyung Park ◽  
Kwang-sig Lee ◽  
Bo Kyoung Seo ◽  
Kyu Ran Cho ◽  
Ok Hee Woo ◽  
...  

AbstractRadiogenomics investigates the relationship between imaging phenotypes and genetic expression. Breast cancer is a heterogeneous disease that manifests complex genetic changes and various prognosis and treatment response. We investigate the value of machine learning approaches to radiogenomics using low-dose perfusion computed tomography (CT) to predict prognostic biomarkers and molecular subtypes of invasive breast cancer. This prospective study enrolled a total of 723 cases involving 241 patients with invasive breast cancer. The 18 CT parameters of cancers were analyzed using 5 machine learning models to predict lymph node status, tumor grade, tumor size, hormone receptors, HER2, Ki67, and the molecular subtypes. The random forest model was the best model in terms of accuracy and the area under the receiver-operating characteristic curve (AUC). On average, the random forest model had 13% higher accuracy and 0.17 higher AUC than the logistic regression. The most important CT parameters in the random forest model for prediction were peak enhancement intensity (Hounsfield units), time to peak (seconds), blood volume permeability (mL/100 g), and perfusion of tumor (mL/min per 100 mL). Machine learning approaches to radiogenomics using low-dose perfusion breast CT is a useful noninvasive tool for predicting prognostic biomarkers and molecular subtypes of invasive breast cancer.


Viruses ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 142 ◽  
Author(s):  
Steven J. Erly ◽  
Joshua T. Herbeck ◽  
Roxanne P. Kerani ◽  
Jennifer R. Reuer

Molecular cluster detection can be used to interrupt HIV transmission but is dependent on identifying clusters where transmission is likely. We characterized molecular cluster detection in Washington State, evaluated the current cluster investigation criteria, and developed a criterion using machine learning. The population living with HIV (PLWH) in Washington State, those with an analyzable genotype sequences, and those in clusters were described across demographic characteristics from 2015 to2018. The relationship between 3- and 12-month cluster growth and demographic, clinical, and temporal predictors were described, and a random forest model was fit using data from 2016 to 2017. The ability of this model to identify clusters with future transmission was compared to Centers for Disease Control and Prevention (CDC) and the Washington state criteria in 2018. The population with a genotype was similar to all PLWH, but people in a cluster were disproportionately white, male, and men who have sex with men. The clusters selected for investigation by the random forest model grew on average 2.3 cases (95% CI 1.1–1.4) in 3 months, which was not significantly larger than the CDC criteria (2.0 cases, 95% CI 0.5–3.4). Disparities in the cases analyzed suggest that molecular cluster detection may not benefit all populations. Jurisdictions should use auxiliary data sources for prediction or continue using established investigation criteria.


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