scholarly journals Effect of Contrast Agent Administration on Size-Specific Dose Estimates (SSDE) Calculations based on Water Equivalent Diameter in CT Head Examinations

Author(s):  
Moh. Shofi Nur Utami ◽  
Heri Sutanto ◽  
Choirul Anam

Size-specific dose estimate (SSDE) is dose metrics of computed tomography, to calculate SSDE we first calculate the patient's body size. In CT head examination, the head size is better to use water-equivalent diameter (Dw), because Dw considers tissue attenuation. CT Head examination with contrast agent increased patient attenuation and increased Dw. In this study, we observed the effect of contrast agent on the Dw value on the axial image of patients with CT head examination. A total of 96 patients underwent a CT Head examination with a contrast agent in the two CT scan modalities. 46 patients underwent CT Head examination with contrast agent using CT Scanner Toshiba Alexion 16 and 50 patients underwent CT Head examination with contrast agent using CT Scanner GE Medical System Optima CT660. Dw value is calculated automatically using IndoseCT version 20b. We compared the Dw pre-contrast and Dw post-contrast values with the two independent sample t-test statistical analysis. To consider the effect of changing Dw values on SSDE we normalized dose coefficient (NDC). We did not find a significant difference between Dw pre-contrast and Dw post-contrast. The P-value statistical analysis results for the CT Scanner Toshiba Alexion 16 and the CT Scanner GE Medical System Optima CT660 were 0.65 and 0.45. The NDC change in this study was below 20%. On CT Head examination, the Dw and SSDE pre-contrast values can be used to estimate the Dw and SSDE post-contrast values.

2009 ◽  
Vol 66 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Drenka Turjacanin-Pantelic ◽  
Dragana Bojovic-Jovic ◽  
Biljana Arsic ◽  
Eliana Garalejic

Background/Aim. A modern approach to surgical treatment of tuboperitoneal infertility is based on laporascopic techniques. The aim of this study was to compare results of tuboperitoneal infertility treatment by the use of laparoscopy and classical laparotomy. Methods. A retrospectiveprospective study on 66 women treated operatively form tuboperitoneal infertility was performed. Data from patient's anamnesis and those related to the surgical treatment results, obtained by the use of an inquiry, were used in retrospective and prospective analysis, respectively. Chi-square test was used in statistical analysis. P value < 0.05 was considered significant. Results. Classical laparotomy was used on 34 women in a period from 1996 to 1997, while 32 women were operated laparoscopically in a period from 1999 to 2000. The results were as follows: a total number of conceived women was 16 (24%), seven in the group I (20.6%) and nine in the group II (28.1%); 13 women were with one pregnancy, six in the group I (17.6%) and seven in the group II (22%). Twice pregnant were three women, one in the group I (2.9%) and two in the group II (6.2%). The resulting pregnancies were: five women with abortion spontaneous, two in the group I (5.9%) and three in the group II (9.4%); two women with extrauterine pregnancy in the group I (5.9%); three with pretemporal birth, one in the group I (2.9%) and two in the group II (6.2%), while six women were with the temporal birth, two in the group I (5.9%) and four in the group II (12.5%). Statistical analysis showed that there was no significant difference in the results between these two groups. Conclusion. Surgical treatment of tubeperitoneal infertility, regardless of the used methods (classical laparotomy or laparoscopy) was successful in a great number of women. These methods have a great advantage over in vitro fertilization, and they should not be ignored.


2014 ◽  
Vol 3 (1) ◽  
pp. 27-41 ◽  
Author(s):  
B.R. Purnima ◽  
N. Sriraam ◽  
U. Krishnaswamy ◽  
K. Radhika

Electroencephalogram (EEG) signals derived from polysomnography recordings play an important role in assessing the physiological and behavioral changes during onset of sleep. This paper suggests a spike rhythmicity based feature for discriminating the wake and sleep state. The polysomnography recordings are segmented into 1 second EEG patterns to ensure stationarity of the signal and four windowing scheme overlaps (0%, 50%, 60% and 75%)of EEG pattern are introduced to study the influence of the pre-processing procedure. The application of spike rhythmicity feature helps to estimate the number of spikes from the given pattern with a threshold of 25%.Then non parametric statistical analysis using Wilcoxon signed rank test is introduced to evaluate the impact of statistical measures such as mean, standard deviation, p-value and box-plot analysis under various conditions .The statistical test shows significant difference between wake and sleep with p<0.005 for the applied feature, thus demonstrating the efficiency of simple thresholding in distinguishing sleep and wake stage .


2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 15108-15108
Author(s):  
P. Niravath ◽  
T. Hayes ◽  
S. Hilsenbeck

15108 Background: Screening known cirrhotics for hepatocellular cancer (HCC) has long been a contentious topic. Studies to date have failed to conclusively prove or disprove the validity of AFP and hepatic ultrasound as screening mechanisms for HCC among cirrhotics, particularly in the American population. It is not clear whether these screening mechanisms provide any benefit in terms of reduced morbidity and mortality. Methods: The study examined all cirrhotics who developed HCC at the Houston Veterans Affairs Medical Center between 1999 and 2005. Those who were screened with AFP and/or imaging (either ultrasound, triphasic liver protocol CT, or MRI) were compared to those patients who were not screened at all. The screened and unscreened patients were compared in terms of Barcelona Clinic Liver Cancer Stage (BCLC) at the time of diagnosis. Results: Statistical analysis revealed a significant difference between the screened and unscreened groups in terms of BCLC stage at diagnosis, with the unscreened group being diagnosed at later stages than the screened group. Of the 155 patients observed, 26 were appropriately screened, and 129 were not. The BCLC stages at diagnosis for the two groups are shown in the table . The different trend in the two groups was found to be statistically significant with a p-value of 0.004. Furthermore, among the screened group, no particular method of screening (AFP vs. imaging vs. combination) was shown to be superior to another. Conclusions: Screening for HCC among cirrhotics using AFP and/or imaging every 6 months does correlate with HCC diagnosis at an earlier BCLC stage, thus portending better treatment options and improved prognosis. Therefore, screening all known cirrhotics for HCC may lead to decreased mortality. [Table: see text] No significant financial relationships to disclose.


Author(s):  
Ming Hei (Alan) Leung ◽  
BCIT School of Health Sciences, Environmental Health ◽  
Bobby Sidhu

  Introduction: Commuters spend countless hours within tightly confined spaces with limited ventilation that may be filled with many contaminants. By analyzing if there is a significant difference between levels of carbon dioxide between rush and non-rush hour conditions, it can be determined if some commuters are subjected to poorer levels of air quality during certain times of the day. Objectives: The primary objective of this study is to understand whether there are significant ventilation deficiencies during rush compared to non-rush hour times in urban transport microenvironments. Methods: Analysis of urban transport microenvironments was done using the TSI brand QTrak Indoor Air Quality (IAQ) Monitor to gather data on carbon dioxide at 1-minute intervals on the 99 B-line express bus that runs between Broadway and Commercial Skytrain Station and the Broadway and Cambie Street Skytrain Station. Results: A one tailed T-test was done on the NCSS 9 statistical software to compare if rush hour urban microenvironments had significantly higher concentrations of carbon dioxide than when compared to non-rush hour. Statistical analysis determined that since the P-value was well above the alpha level of 0.05 (i.e. P<0.05), it gives reason to accept the null hypothesis, which states that rush hour concentrations were not higher than non-rush hour. Conclusion: Statistical analysis determined that the overall concentrations of carbon dioxide during rush hour were not significantly higher than non-rush hour times. This result may have been attributed to conditions and factors during data collection that could not be controlled by the researcher. Due to the length of the route, exposure times were found to be within time-weighted averages as set out by the American Conference of Industrial Hygienists (ACGIH), though it was still not within the recommended limit of 1000 ppm as set out by the American Society of Heating, Refrigeration and Air-Conditioning (ASHRAE).  


2016 ◽  
Vol 1 (3) ◽  
pp. 131-137
Author(s):  
Indrarini Listyowati ◽  
Rista D Soetikno ◽  
Leni Santiana

Background: Computed tomography (CT) is one of the diagnostic imaging tool that is most commonly available in hospitals today. But unlike Magnetic Resonance Imaging (MRI) and nuclear medicine imaging modalities, CT has not been considered as a molecular imaging modality because it does not have a specifc-targeted contrast agents. Diagnostic quality of CT scans can be improved by using specifc-targeted contrast agents. Gold nanoparticles (AuNPs) can be used as X-ray contrast agents that can overcome some of the limitations of the iodine-based contrast agents. Higher atomic numbers than iodine and its ability to be able to bind to the dendrimer support that AuNPS could be developed as a specifc-targeted contrast agents.Objectives: The purpose of this study was to determine the enhancement relationship of AuNPs-Poly(amido)amine in the rat liver with di?erent concentration and delay time on CT scans.Materials and Methods: This research is an experimental study with a statistical analysis to determine enhancement di?erences on rat liver given AuNPs-PAMAM with di?erent concentration and delay time. The samples were divided into 4 groups, each consisting of 6 rats. The independent variables in this study were the delay time and the concentration of AuNPs-PAMAM, the dependent variables was the enhancement on rat liver.Results: The results obtained showed that the average value enhancement of AuNPs-PAMAM is highest in 10 minutes delay time at a concentration of 1 mg/dL. Statistical analysis showed that there were signifcant di?erences between AuNPs-PAMAM contrast enhancement in the rat liver with di?erent concentration and delay time on CT scan with p-value less than alpha (0.000 <0.05).Conclusions: Concentration and delay time contribute to the average value enhancement of AuNPs-PAMAM contrast agent on CT scan. This new type of contrast agent can be further developed as a more specifc-targeted contrast agent for CT scan examination.


2021 ◽  
Vol 15 (1) ◽  
pp. 186-193
Author(s):  
Sarah Sukeri ◽  
Azizah Ab Karem ◽  
Evana Kamarudin ◽  
Mazura Bahari

Food poisoning is one of the riskiest illnesses caused by an organism like bacteria, viruses and parasites, which can contaminate food at any stage of food production. Most reports are associated with bacterial contamination through the food preparation process. Researcher nowadays attempts to discover a safer agent to use in food preparation as a food preservative agent. Thus, the potential of Rhodomyrtus tomentosa leaves as an antimicrobial agent was explored in this study. It was tested against two bacteria which are Staphylococcus aureus (gram-positive) and Eschericia coli (gram-negative). Antimicrobial activity of methanol and aqueous R. tomentosa leaves extract was compared using gram staining, bacterial identification, antimicrobial sensitivity testing (AST), minimal inhibitory concentration (MIC), minimal bactericidal concentration (MBC) and statistical analysis. The disc diffusion technique was used for AST where the mean area of inhibition methanol and aqueous extract against S. aureus was 18 mm and 16 mm respectively, whereas there was no area of inhibition for E. coli. MIC was done to determine the minimum concentration of the extract needed to inhibit the bacteria. After that, MBC was performed to confirm the previous MIC result. Statistical analysis was done by conduct it through SPSS software program. Then, the result for S. aureus is obtained from finding its p-value. Statistically, a significant difference between the two bacteria was analyzed by using independent t-test. A result of p-value less than 0.05 was considered significantly different as one another. Statistical analysis showed no significant difference between methanol and aqueous extract on antimicrobial activity. In conclusion, both aqueous and methanol leaves R. tomentosa yielded similar antibacterial activity which susceptible to S. aureus and can be used safely toward foodborne pathogen.


2015 ◽  
Vol 09 (03) ◽  
pp. 340-345 ◽  
Author(s):  
Shaam Saeed ◽  
Nada Bshara ◽  
Juliana Trak ◽  
Ghiath Mahmoud

ABSTRACT Objectives: To study the effect of water, halloumi cheese and sugar-free (SF) chewing gum on plaque pH recovery after the intake of sweetened PLAs. Settings and Design: A randomized clinical trial was conducted on 17 children (10 females, 7 males) aged 11–12 years with DFT/dft of more than 3. Materials and Methods: Each volunteer tested paracetamol and ibuprofen suspension alone or followed with water, halloumi cheese or SF gum, as well as 10% sucrose and 10% sorbitol as controls. Plaque pH was measured using the sampling method before and after 5, 10, 15, 20, 30 min of ingestion. Statistical Analysis: Statistical analysis was performed using analysis of variance followed by least significant difference test to assess minimum pH (min pH), maximum pH drop (ΔpH), and the area under baseline pH, and P value was set as 0.05. Results: Both ibuprofen and paracetamol were not significantly different from 10% sucrose in terms of min pH, ΔpH, and area under baseline pH except for min pH of ibuprofen (P = 0.034). Water and halloumi cheese did not have a significant effect on plaque pH recovery after the intake of both analgesics as min pH, ΔpH, and area under baseline pH were similar to 10% sucrose except for min pH of ibuprofen + water (P = 0.048). However, plaque pH variables after chewing SF gum for 20 min were similar to 10% sorbitol. Conclusion: Chewing SF gum immediately after the intake of sweetened PLAs for 20 min restores plaque pH and could be recommended as a complementary aid in caries prevention.


2018 ◽  
Vol 34 (05) ◽  
pp. 359-362 ◽  
Author(s):  
Rowena Sudario-Lumague ◽  
Yuan-Cheng Chiang ◽  
Tsan-Shiun Lin

Background Perceived gender-related differences in surgical skills could limit opportunities available for any aspiring surgeon. There should be more available literature and logical analysis of these observations. The objective of this study is to evaluate the microsurgical skills of male and female medical students using a standard scale in the laboratory. Methods This study included medical students enrolled in the Kaohsiung Chang Gung Memorial Hospital from 2002 to 2015 who were evaluated by a senior consultant for their microsurgical skills. A standard numeric scale was used to evaluate their suturing technique after basic microsurgical training. Differences in the scores between male and female medical students were evaluated using statistical analysis. Results A total of 578 medical students were included in the study. There were 393 males (68%) and 185 females (32%). Using statistical analysis, there is no significant difference in the distribution of scores (p-Value = 0.78) and mean scores (p-Value = 0.75) between the two groups. Conclusions This study shows that microsurgical skills of male and female medical students are similar. Equal opportunities in the eventual pursuit of the surgical specialties should be available regardless of gender.


2020 ◽  
Vol 6 (2) ◽  
pp. 33-38
Author(s):  
Amrita Pritam ◽  
Nivedita Mall

Background and Aim: For miscellaneous purposes, the prosthodontists and dental laboratory technicians usually attempt repeated pouring of the impression in order to avoid expenses and curb upon the chair-side time. There are numerous factors which can affect dimensions of subsequent casts on repeated pouring. These include the process of polymerization, temperature and the material used to fabricate the replica of working cast. The sole aim of this study was to evaluate if repeated pouring of addition silicone impression would influence the dimensional accuracy of resultant casts. Materials & Methods: Addition silicone impression material along with tray adhesive were used to evaluate the influence of repeat pours on the dimensional accuracy of resultant casts at various time intervals i.e. at 15 minutes, 75 minutes, 24 hours and 7 days. Vision measurement machine was used for measurement of dimensions. A metal control model of 8*6*2 cm was made with abutments. Various dimensional markings and measurements (for inter-abutment distance & intra-abutment distance) were completed. All 80 resultant casts were along with the master model was dimensionally evaluated with “Vision Measurement Machine”. Statistical Analysis and Results: Statistical analysis was completed by SPSS (statistical package for social sciences) version 21.0 and Epi-info version 3.0. The result of this study showed that working dies obtained from Addition silicone at various time intervals i.e. 15 minutes, 75 minutes, 24 hours and 7 days exhibited insignificant dimension changes clinically. The p-value was taken significant when less than 0.05 (p<0.05) and Confidence interval of 95% was taken. Post-Hoc Bonferroni test showed no significant difference for the inter-interval comparison of mean inter-abutment distance (Line 2-3). Conclusion: Within the limitations of the study authors concluded that the addition silicone impression material could be preferred material in the field of prosthodontics for repeated pouring up-to 7 days due to its favorable qualities like dimensional accuracy and stability, elastic recovery from undercuts, low creep and moderate to high tear resistance.


Author(s):  
Sarah Maria Ramos ◽  
Daniela Maciel da Silva ◽  
Daniela Vieira Buchaim ◽  
Rogério Leone Buchaim ◽  
Mauro Audi

The purpose of this study was to evaluate the inspiratory and expiratory muscle strength of individuals affected by stroke and to compare it with the predicted values in the literature considering their corresponding age. Respiratory muscle strength was evaluated in 22 elderly people who had sequels of stroke, four with right hemiparesis, 16 with left hemiparesis and two with bilateral, of ages ranging from 34 to 82 years. The collected data were submitted to statistical analysis using a Mann–Whitney test to evaluate if there was a significant difference in the average data collected when compared with a mean of the predicted data in the literature. Fourteen men and eight women were evaluated, who obtained mean values of 71.85 cmH2O and 57.75 cmH2O, respectively, for a maximal inspiratory pressure (MIP), and when compared to the predicted values for men and women, 105.41 cmH2O (p-value 0.0019) and 80.57 cmH2O (p-value 0.00464) were significantly lower. For a maximal expiratory pressure (MEP), the mean value obtained for men was 62.28 cmH2O and 49.5 cmH2O for women, whereas the predicted values in the literature were 114.79 cmH2O (p-value < 0.0001) and 78, 46 cmH2O (p-value 0.0059), respectively. In the statistical analysis, it was possible to notice that the studied population did not reach the predicted age indexes and that there was a significant difference between the median columns. In conclusion, there is a weakness in the respiratory muscles of hemiparetic men and women due to stroke.


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