Comparison Analysis on Medical Data Mining for Drug Suggestion

2016 ◽  
pp. 567-570
Author(s):  
Gandhi Jabakuma ◽  
W. Mercy
Keyword(s):  
Adverse Event ◽  
Safety Assessment ◽  
Back Reaction ◽  
Comparison Analysis ◽  
Medical Field ◽  
Drug Detection ◽  
Drug Adverse Event ◽  
Pharmaceutical Industries ◽  
The Impact ◽  
Dynamic Domain

The drug back reaction measurement is the most important part of the drug safety assessment. In the early days, the measurement is made by trailing the impact after the course of many examples. In the pharmaceutical industries, the most interesting research topic is adverse drug detection which rules the world. In the 21century , the data available in the medical field gave an important development in motivating of an adverse event. Recently, many people put forward the statistical data and also the mining methods which are largely implemented to detect the drug adverse event. In the following paper, we explain more methods explained by expert’s researchers in the dynamic domain of data.

scholarly journals 10.B. Workshop: Corporate influence on science – what is happening and what can be done?

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
◽  
Keyword(s):  
Fossil Fuels ◽  
Conflicts Of Interest ◽  
Research Process ◽  
Policy Outcomes ◽  
Policy And Practice ◽  
Industry Funding ◽  
Corporate Influence ◽  
Pharmaceutical Industries ◽  
The Impact ◽  
Funding Research

Abstract The role of the corporate sector in research sponsorship is growing. So too is the evidence that corporations whose products are potentially damaging to health or the environment influence science and the ways in which science is used in policy and practice. Such efforts are a key part of corporate attempts to maintain or increase the consumption or use of industry products, and to secure favourable policy outcomes. The products and practices of corporations are responsible for a growing proportion of the global disease burden. Non-communicable diseases, many driven by consumption of unhealthy commodities and exposure to chemicals, account for over 73 percent of global deaths. It is increasingly important to understand the complex and multifaceted ways corporations seek to influence science; the impact these strategies have; and the ways this influence can be addressed. This workshop brings together global experts to explore these issues. Drawing on examples from several industries (e.g. tobacco, alcohol, food, and pharmaceuticals), it aims to: Increase understanding of the ways corporations whose products are potentially damaging to health influence science. We present a newly developed, evidence-based typology which draws together the vast existing literature in this field, to present a simplified way of understanding corporate influence on science. Delegates will be provided with materials that provide a means for recognising such influence.Examine the influence that corporations have on the first stage in the research process - research agendas. We present examples from tobacco, food and pharmaceutical industries which illustrate the mechanism through which industry funding of science drives researchers to study questions that are favourable to industry. The desired outcome is to maximise research on the benefits of industry products (positioning these products as solutions to complex problems), minimise research on the harms of their products, support their policy and legal positions, and impede potential regulation of their products.Increase awareness of the involvement that corporations have had in altering the mechanisms though which science is used in policymaking. Delegates will hear how corporations promoted and embedded policymaking reforms which increase reliance on and provide a conduit for industry-favourable science.Suggest ways forward concerning management of conflicts of interest in the publication of health research. Here we will discuss the roles that journals can play in governing conflicts of interest and issues of transparency in the publication of academic research.Suggest ways forward for funding research on unhealthy commodities. We present criteria for tobacco industry-supported research funding programs, and discuss the applicability of similar programs for funding research on other unhealthy commodities, and on the practices of other industries such as the fossil fuels industry. Key messages Corporations have been seen to skew evidence bases, manipulate interpretations of science, and influence use of science in policy and practice – such influence is a major threat to public health. This workshop exposes industry tactics in this area and begins to identify ways for dealing with them.

scholarly journals The Irish National Adverse Event Study-2 (INAES-2): longitudinal trends in adverse event rates in the Irish healthcare system

2021 ◽  
pp. bmjqs-2020-011122 ◽  
Author(s):  
Warren Connolly ◽  
Natasha Rafter ◽  
Ronan M Conroy ◽  
Cornelia Stuart ◽  
Anne Hickey ◽  
...  
Keyword(s):  
Adverse Event ◽  
Adverse Events ◽  
Positive Impact ◽  
Retrospective Chart Review ◽  
Published Data ◽  
National Programmes ◽  
Event Rates ◽  
Hospital Associated Infections ◽  
Design And Methods ◽  
The Impact

ObjectivesTo quantify the prevalence and nature of adverse events in acute Irish hospitals in 2015 and to assess the impact of the National Clinical Programmes and the National Clinical Guidelines on the prevalence of adverse events by comparing these results with the previously published data from 2009.Design and methodsA retrospective chart review of 1605 admissions to eight Irish hospitals in 2015, using identical methods to those used in 2009.ResultsThe percentage of admissions associated with one or more adverse events was unchanged (p=0.48) at 14% (95% CI=10.4% to 18.4%) in 2015 compared with 12.2% (95% CI=9.5% to 15.5%) in 2009. Similarly, the prevalence of preventable adverse events was unchanged (p=0.3) at 7.4% (95% CI=5.3% to 10.5%) in 2015 compared with 9.1% (95% CI=6.9% to 11.9%) in 2009. The incidence densities of preventable adverse events were 5.6 adverse events per 100 admissions (95% CI=3.4 to 8.0) in 2015 and 7.7 adverse events per 100 admissions (95% CI=5.8 to 9.6) in 2009 (p=0.23). However, the percentage of preventable adverse events due to hospital-associated infections decreased to 22.2% (95% CI=15.2% to 31.1%) in 2015 from 33.1% (95% CI=25.6% to 41.6%) in 2009 (p=0.01).ConclusionAdverse event rates remained stable between 2009 and 2015. The percentage of preventable adverse events related to hospital-associated infection decreased, which may represent a positive impact of the related national programmes and guidelines.

Evaluation of Drug Adverse Event Intake and Reporting in a Medical Information Service

2011 ◽  
Vol 45 (6) ◽  
pp. 767-773 ◽  
Author(s):  
Pamela D. Allen ◽  
Robert J. Fuentes ◽  
Michael J. Hoopes ◽  
Greg Susla
Keyword(s):  
Adverse Event ◽  
Medical Information ◽  
Information Service ◽  
Drug Adverse Event

scholarly journals Examining Socioeconomic and Computational Aspects of Vaccine Pharmacovigilance

2019 ◽  
Vol 2019 ◽  
pp. 1-15 ◽  
Author(s):  
Vasiliki Soldatou ◽  
Anastasios Soldatos ◽  
Theodoros Soldatos
Keyword(s):  
Adverse Event ◽  
Enrichment Analysis ◽  
Vaccine Safety ◽  
Molecular Data ◽  
Adverse Event Reporting ◽  
Computational Techniques ◽  
Behavioral Determinants ◽  
Clinical Patient ◽  
Adverse Event Data ◽  
The Impact

Background. Vaccine pharmacovigilance relates to the detection of adverse events, their assessment, understanding, and prevention, and communication of their risk to the public. These activities can be tedious and long lasting for regulatory authority scientists and may be affected by community practices and public health policies. To better understand underlying challenges, we examined vaccine adverse event reports, assessed whether data-driven techniques can provide additional insight in safety characterization, and wondered on the impact of socioeconomic parameters. Methods. First, we integrated VAERS content with additional sources of drug and molecular data and examined reaction and outcome occurrence by using disproportionality metrics and enrichment analysis. Second, we reviewed social and behavioral determinants that may affect vaccine pharmacovigilance aspects. Results. We describe our experience in processing more than 607000 vaccine adverse event reports and report on the challenges to integrate more than 95500 VAERS medication narratives with structured information about drugs and other therapeutics or supplements. We found that only 12.6% of events were serious, while 8.97% referred to polypharmacy cases. Exacerbation of serious clinical patient outcomes was observed in 8.88% VAERS cases in which drugs may interact with vaccinations or with each other, regardless of vaccine activity interference. Furthermore, we characterized the symptoms reported in those cases and summarized reaction occurrence among vaccine-types. Last, we examine socioeconomic parameters and cost-management features, explore adverse event reporting trends, and highlight perspectives relating to the use and development of digital services, especially in the context of personalized and collaborative health-care. Conclusions. This work provides an informative review of VAERS, identifies challenges and limitations in the processing of vaccine adverse event data, and calls for the better understanding of the socioeconomic landscape pertaining vaccine safety concerns. We expect that adoption of computational techniques for integrated safety assessment and interpretation is key not only to pharmacovigilance practice but also to stakeholders from the entire healthcare system.

scholarly journals A REVIEW ON THE IMPACT OF THE COVID-19 PANDEMIC ON THE HEALTH CARE SECTOR

2021 ◽  
pp. 1-6
Author(s):  
PRAJITHA BIJU ◽  
PALLAVI K. ◽  
VAGEESH REVADIGAR ◽  
SONAL DSOUZA ◽  
MOHAMMED ASIF IQBAL ◽  
...  
Keyword(s):  
Health Care ◽  
Initial Period ◽  
Health Care Sector ◽  
Healthcare Sector ◽  
Future Challenges ◽  
Artificial Intelligence Technology ◽  
Pharmaceutical Industries ◽  
Impact Problems ◽  
The One ◽  
The Impact

The global crisis of the present era, the COVID-19 pandemic, has changed given new normal ways in many of the sectors. The present review highlights the impact, problems, and challenges faced by major areas of the health care sector due to pandemics and also addresses some of the aspects of upcoming approaches. The healthcare sector is the one sector that is on-demand since this COVID-19 pandemic raised. During the initial period, there was disruption of various services provided by the health care sector due to supply chain management issues and reduction in demand by consumers, quarantine, and lockdown period. The healthcare workers also confronted a huge challenge due to the increased number of cases and shortage of amenities and safety measures. This significantly affected even COVID-19 patients and the general public suffering from other diseases. To fight this issue, research and development (RandD) in pharmaceutical industries with great efforts to explore molecules and save many lives. Gradually innovative ways to strengthen and combat pandemics started emerging. Numeral ways and rules were adopted to prevent, diagnose and cure the disease. Artificial intelligence technology has emerged as one of the boons to address many of the unresolved or time-consuming mysteries. All the divisions of health care sectors have started working more efficiently with adopted new strategies to face future challenges.

scholarly journals Identifying new criteria for assessing the impact on the ecosystem generated by the establishment of Jerusalem artichoke crops on difficult and floodable soils

2021 ◽  
Vol 286 ◽  
pp. 03022
Author(s):  
Florin Nenciu ◽  
Gabriel Nae ◽  
Gabriela Milian ◽  
Iulian Dumitru ◽  
Gheorghe Matei ◽  
...  
Keyword(s):  
Agricultural Land ◽  
Jerusalem Artichoke ◽  
Raw Material ◽  
Biofuel Production ◽  
Land Owners ◽  
Marginal Soils ◽  
Pharmaceutical Industries ◽  
The Impact ◽  
Near Future ◽  
Technical Plant

Jerusalem Artichoke (Helianthus tuberosus L.) is a technical plant that manages to adapt very well to unfriendly environments, even in polluted or poor in nutrients soils and may serve in the near future as an important raw material for the food, chemical, and pharmaceutical industries. Furthermore, the plant is growing rapidly, producing large amounts of biomass and offers the possibility to be harvested up to 2 times a year, therefore presents a high potential to be used in the field of biofuel production. The plant's capacity to multiply easily by developing small tubers in the soil, allowing the production of economically advantageous crops, can be considered an advantage for biofuel producers, however this feature might be a drawback for agricultural land owners considering the very invasive behavior. The present paper aim to assess two Jerusalem Artichokes crops established on marginal soils, assessing productivity and the extensive impact on the ecosystem, paying a special attention to plant invasiveness tendencies.

scholarly journals INTEGRATING THE IMPACT OF COUNTRY OF ORIGIN (COC) AND CONSUMER ETHNOCENTRISM (CE) ON GLOBAL MARKETING (GM) AND GROWING CONSUMER TRENDS (GCT) EVIDENCES FROM PHARMACEUTICAL INDUSTRIES IN INDONES

2017 ◽  
Vol 11 (1) ◽  
Author(s):  
Kardison Lumban Batu
Keyword(s):  
Structural Equation Modeling ◽  
Structural Equation ◽  
Country Of Origin ◽  
Equation Modeling ◽  
Global Marketing ◽  
Consumer Ethnocentrism ◽  
Independent Variables ◽  
Pharmaceutical Industries ◽  
The Impact

The current research is empirically investigated the impact of country of origin and consumer ethnocentrism on growing customer trend directly also through global marketing as mediating variable. It is also assessed the impact of global marketing on growing consumer trend. By deploying Structural Equation Modeling with AMOS, three independent variables were analyzed, country of origin (CoC), global marketing (GM), consumer ethnocentrism (CE) and growing consumer trend (GCT) as dependent variable. The findings showed that both country of origin (CoC) and consumer ethnocentrism (CE) have significant effect on global marketing (GM) as well as on growing consumer trend (GCT). Further, global marketing (GM) successfully mediated and showed significant effect of both country of origin and consumer ethnocentrism. Finally global marketing has significant impact on growing consume trend.

scholarly journals Dairy-Derived and Egg White Proteins in Enhancing Immune System Against COVID-19

2021 ◽  
Vol 8 ◽  
Author(s):  
Gaber El-Saber Batiha ◽  
Mohammed Alqarni ◽  
Dina A. B. Awad ◽  
Abdelazeem M. Algammal ◽  
Richard Nyamota ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Nutritional Intervention ◽  
Bioactive Components ◽  
Multiple Organs ◽  
Cell Immunity ◽  
Egg White Proteins ◽  
Pharmaceutical Industries ◽  
Dietary Components ◽  
The Impact ◽  
Global Health Challenge

Coronavirus disease (COVID-19) is a global health challenge, caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) triggers a plethora of respiratory disturbances and even multiple organs failure that can be fatal. Nutritional intervention is one of the key components toward to a proper management of COVID-19 patients, especially in those requiring medication, and should thus be considered the first-line treatment. Immuno-modulation and -stimulation are currently being explored in COVID-19 management and are gaining interest by food and pharmaceutical industries. Various dietary combinations, bioactive components, nutrients and fortified foods have been reported to modulate inflammation during disease progression. Dietary combinations of dairy-derived products and eggs are gaining an increasing attention given the huge immunomodulatory and anti-inflammatory properties attributed to some of their chemical constituents. Eggs are complex dietary components containing many essential nutrients and bioactive compounds as well as a high-quality proteins. Similarly, yogurts can replenish beneficial bacteria and contains macronutrients capable of stimulating immunity by enhancing cell immunity, reducing oxidative stress, neutralizing inflammation and regulating the intestinal barriers and gut microbiome. Thus, this review highlights the impact of nutritional intervention on COVID-19 management, focusing on the immunomodulatory and inflammatory effects of immune-enhancing nutrients.

scholarly journals What Happens When People with Depression Gather Online?

2021 ◽  
Vol 18 (16) ◽  
pp. 8762
Author(s):  
Xuening Wang ◽  
Xianyun Tian ◽  
Xuwei Pan ◽  
Dongxu Wei ◽  
Qi Qi
Keyword(s):  
Online Community ◽  
Mental Disease ◽  
Activity Patterns ◽  
Comparison Analysis ◽  
The Impact

Depression is a common mental disease that impacts people of all ages and backgrounds. To meet needs that cannot otherwise be met, people with depression or who tend to suffer from depression often gather in online depression communities. However, since joining a depression community exposes members to the depression of others, the impact of such communities is not entirely clear. This study therefore explored what happens when people with depression gather in Sina Weibo’s Depression Super Topic online community. Through website crawling, postings from Depression Super Topic were compared with postings from members’ regular timelines with respect to themes, emotions disclosed, activity patterns, and the number of likes and comments. Topics of distilled postings covering support, regulations, emotions and life sharing, and initiating discussions were then coded. From comparison analysis, it was found that postings in the Depression Super Topic community received more comments and disclosed more emotions than regular timelines and that members were more active in the community at night. This study offers a picture of what occurs when people with depression gather online, which helps better understand their issues and therefore provide more targeted support.

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