scholarly journals Applications of Machine Learning and Deep Learning in Ultrasound Imaging

Author(s):  
Siddhika Arunachalam

Ultrasound (US) imaging (sonography) is the most frequently performed cross-sectional diagnostic imaging modality in the field of medicine. It is non-ionizing, portable, cost-effective, and capable of real-time image acquisition and display. US is a rapidly evolving technology with substantial opportunities and challenges. Challenges include limited image quality control and high inter- and intra-operator variability. As US devices become smaller, due to progressive miniaturization of US devices in the last decade, increased computational capability can contribute significantly to decreasing variability through advanced image processing. In this paper, leading Machine Learning (ML) and Deep Learning (DL) approaches and research directions in US, with an emphasis on recent ML and DL advances is discussed. An outlook on future opportunities for ML and DL techniques to further improve clinical workflow and US-based disease diagnosis and characterization is also presented.

2020 ◽  
Vol 15 ◽  
Author(s):  
Deeksha Saxena ◽  
Mohammed Haris Siddiqui ◽  
Rajnish Kumar

Background: Deep learning (DL) is an Artificial neural network-driven framework with multiple levels of representation for which non-linear modules combined in such a way that the levels of representation can be enhanced from lower to a much abstract level. Though DL is used widely in almost every field, it has largely brought a breakthrough in biological sciences as it is used in disease diagnosis and clinical trials. DL can be clubbed with machine learning, but at times both are used individually as well. DL seems to be a better platform than machine learning as the former does not require an intermediate feature extraction and works well with larger datasets. DL is one of the most discussed fields among the scientists and researchers these days for diagnosing and solving various biological problems. However, deep learning models need some improvisation and experimental validations to be more productive. Objective: To review the available DL models and datasets that are used in disease diagnosis. Methods: Available DL models and their applications in disease diagnosis were reviewed discussed and tabulated. Types of datasets and some of the popular disease related data sources for DL were highlighted. Results: We have analyzed the frequently used DL methods, data types and discussed some of the recent deep learning models used for solving different biological problems. Conclusion: The review presents useful insights about DL methods, data types, selection of DL models for the disease diagnosis.


Author(s):  
Tausifa Jan Saleem ◽  
Mohammad Ahsan Chishti

The rapid progress in domains like machine learning, and big data has created plenty of opportunities in data-driven applications particularly healthcare. Incorporating machine intelligence in healthcare can result in breakthroughs like precise disease diagnosis, novel methods of treatment, remote healthcare monitoring, drug discovery, and curtailment in healthcare costs. The implementation of machine intelligence algorithms on the massive healthcare datasets is computationally expensive. However, consequential progress in computational power during recent years has facilitated the deployment of machine intelligence algorithms in healthcare applications. Motivated to explore these applications, this paper presents a review of research works dedicated to the implementation of machine learning on healthcare datasets. The studies that were conducted have been categorized into following groups (a) disease diagnosis and detection, (b) disease risk prediction, (c) health monitoring, (d) healthcare related discoveries, and (e) epidemic outbreak prediction. The objective of the research is to help the researchers in this field to get a comprehensive overview of the machine learning applications in healthcare. Apart from revealing the potential of machine learning in healthcare, this paper will serve as a motivation to foster advanced research in the domain of machine intelligence-driven healthcare.


Author(s):  
Shradha Verma ◽  
Anuradha Chug ◽  
Amit Prakash Singh ◽  
Shubham Sharma ◽  
Puranjay Rajvanshi

With the increasing computational power, areas such as machine learning, image processing, deep learning, etc. have been extensively applied in agriculture. This chapter investigates the applications of the said areas and various prediction models in plant pathology for accurate classification, identification, and quantification of plant diseases. The authors aim to automate the plant disease identification process. To accomplish this objective, CNN has been utilized for image classification. Research shows that deep learning architectures outperform other machine learning tools significantly. To this effect, the authors have implemented and trained five CNN models, namely Inception ResNet v2, VGG16, VGG19, ResNet50, and Xception, on PlantVillage dataset for tomato leaf images. The authors analyzed 18,160 tomato leaf images spread across 10 class labels. After comparing their performance measures, ResNet50 proved to be the most accurate prediction tool. It was employed to create a mobile application to classify and identify tomato plant diseases successfully.


2020 ◽  
Vol 10 (11) ◽  
pp. 2707-2713
Author(s):  
Zheng Sun ◽  
Xiangyang Yan

Intravascular photoacoustic tomography (IVPAT) is a newly developed imaging modality in the interventional diagnosis and treatment of coronary artery diseases. Incomplete acoustic measurement caused by limitedview scanning of the detector in the vascular lumen results in under-sampling artifacts and distortion in the images reconstructed by using the standard reconstruction methods. A method for limited-view IVPAT image reconstruction based on deep learning is presented in this paper. A convolutional neural network (CNN) is constructed and trained with computer-simulated image data set. Then, the trained CNN is used to optimize the cross-sectional images of the vessel which are recovered from the incomplete photoacoustic measurements by using the standard time-reversal (TR) algorithm to obtain the images with the improved quality. Results of numerical demonstration indicate that the method can effectively reduce the image distortion and artifacts caused by the limited-view detection. Furthermore, it is superior to the compressed sensing (CS) method in recovering the unmeasured information of the imaging target with the structural similarity around 10% higher than CS reconstruction.


2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
O. Obulesu ◽  
Suresh Kallam ◽  
Gaurav Dhiman ◽  
Rizwan Patan ◽  
Ramana Kadiyala ◽  
...  

Cancer is a complicated worldwide health issue with an increasing death rate in recent years. With the swift blooming of the high throughput technology and several machine learning methods that have unfolded in recent years, progress in cancer disease diagnosis has been made based on subset features, providing awareness of the efficient and precise disease diagnosis. Hence, progressive machine learning techniques that can, fortunately, differentiate lung cancer patients from healthy persons are of great concern. This paper proposes a novel Wilcoxon Signed-Rank Gain Preprocessing combined with Generative Deep Learning called Wilcoxon Signed Generative Deep Learning (WS-GDL) method for lung cancer disease diagnosis. Firstly, test significance analysis and information gain eliminate redundant and irrelevant attributes and extract many informative and significant attributes. Then, using a generator function, the Generative Deep Learning method is used to learn the deep features. Finally, a minimax game (i.e., minimizing error with maximum accuracy) is proposed to diagnose the disease. Numerical experiments on the Thoracic Surgery Data Set are used to test the WS-GDL method's disease diagnosis performance. The WS-GDL approach may create relevant and significant attributes and adaptively diagnose the disease by selecting optimal learning model parameters. Quantitative experimental results show that the WS-GDL method achieves better diagnosis performance and higher computing efficiency in computational time, computational complexity, and false-positive rate compared to state-of-the-art approaches.


2020 ◽  
Vol 10 (2) ◽  
pp. 21 ◽  
Author(s):  
Gopi Battineni ◽  
Getu Gamo Sagaro ◽  
Nalini Chinatalapudi ◽  
Francesco Amenta

This paper reviews applications of machine learning (ML) predictive models in the diagnosis of chronic diseases. Chronic diseases (CDs) are responsible for a major portion of global health costs. Patients who suffer from these diseases need lifelong treatment. Nowadays, predictive models are frequently applied in the diagnosis and forecasting of these diseases. In this study, we reviewed the state-of-the-art approaches that encompass ML models in the primary diagnosis of CD. This analysis covers 453 papers published between 2015 and 2019, and our document search was conducted from PubMed (Medline), and Cumulative Index to Nursing and Allied Health Literature (CINAHL) libraries. Ultimately, 22 studies were selected to present all modeling methods in a precise way that explains CD diagnosis and usage models of individual pathologies with associated strengths and limitations. Our outcomes suggest that there are no standard methods to determine the best approach in real-time clinical practice since each method has its advantages and disadvantages. Among the methods considered, support vector machines (SVM), logistic regression (LR), clustering were the most commonly used. These models are highly applicable in classification, and diagnosis of CD and are expected to become more important in medical practice in the near future.


Processes ◽  
2019 ◽  
Vol 7 (5) ◽  
pp. 265 ◽  
Author(s):  
Mingrui Sun ◽  
Tengfei Min ◽  
Tianyi Zang ◽  
Yadong Wang

(1) Background: Recommendation algorithms have played a vital role in the prediction of personalized recommendation for clinical decision support systems (CDSSs). Machine learning methods are powerful tools for disease diagnosis. Unfortunately, they must deal with missing data, as this will result in data error and limit the potential patterns and features associated with obtaining a clinical decision; (2) Methods: Recent years, collaborative filtering (CF) have proven to be a valuable means of coping with missing data prediction. In order to address the challenge of missing data prediction and latent feature extraction, neighbor-based and latent features-based CF methods are presented for clinical disease diagnosis. The novel discriminative restricted Boltzmann machine (DRBM) model is proposed to extract the latent features, where the deep learning technique is adopted to analyze the clinical data; (3) Results: Proposed methods were compared to machine learning models, using two different publicly available clinical datasets, which has various types of inputs and different quantity of missing. We also evaluated the performance of our algorithm, using clinical datasets that were missing at random (MAR), which were missing at various degrees; and (4) Conclusions: The experimental results demonstrate that DRBM can effectively capture the latent features of real clinical data and exhibits excellent performance for predicting missing values and result classification.


Electronics ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 1421
Author(s):  
Haechan Park ◽  
Nakhoon Baek

With the growth of artificial intelligence and deep learning technology, we have many active research works to apply the related techniques in various fields. To test and apply the latest machine learning techniques in gaming, it will be very useful to have a light-weight game engine for quick prototyping. Our game engine is implemented in a cost-effective way, in comparison to well-known commercial proprietary game engines, by utilizing open source products. Due to its simple internal architecture, our game engine is especially beneficial for modifying and reviewing the new functions through quick and repetitive tests. In addition, the game engine has a DNN (deep neural network) module, with which the proposed game engine can apply deep learning techniques to the game features, through applying deep learning algorithms in real-time. Our DNN module uses a simple C++ function interface, rather than additional programming languages and/or scripts. This simplicity enables us to apply machine learning techniques more efficiently and casually to the game applications. We also found some technical issues during our development with open sources. These issues mostly occurred while integrating various open source products into a single game engine. We present details of these technical issues and our solutions.


2020 ◽  
Author(s):  
Yuhan Yang ◽  
Bo Zheng ◽  
Yixi Wang ◽  
Xuelei Ma

Abstract Objective: To construct a deep-learning convolution neural network (DL-CNN) system for pathological diagnosis of cervical lymph nodes by using computed tomography (CT), fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography (PET), and fused PET/CT images.Materials and methods: A total of 1020 cross-sectional images for each imaging modality was obtained from 211 patients (153 patients with lymphomas and 116 patients with metastases) with enlarged cervical lymph nodes from January 2014 to June 2018. All eligible images were distributed randomly into the training, validation, and testing cohorts with ratios of 70%, 15%, and 15%. We applied eight DL-CNN algorithms with pretrained bases from ImageNet dataset on CT, PET, and fused PET/CT imaging datasets to differentiate lymphomatous nodes from metastatic nodes, respectively. Attention heatmaps of PET and fused PET/CT images generated by class activation mapping (CAM) were used in visualization of class specific regions recognized by the prediction model with best performance. Results: The accuracy of eight deep learning algorithms with pretrained base ranged from 0.650 to 0.981 on PET testing cohort, and from 0.738 to 0.981 on fused PET/CT testing cohort. The VGG16 model on PET images and DenseNet121 model on fused PET/CT images had the best diagnostic performance among all eight algorithms with sensitivity and specificity of 1.000 and 0.963. Class-specific discriminative subregions were highlighted by attention maps for clinical review.Conclusion: A DL-CNN system was developed for classifying metastatic and lymphomatous involvement with favorable diagnostic performance on PET and PET/CT images in patients with enlarged cervical lymph nodes. The further clinical practice of this system may improve quality of the following therapeutic interventions and optimize patients’ outcomes.


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