scholarly journals The Effect of Eccentric Retraining on Sensation of Muscle Pain and Delay Onset Muscle Soreness Markers on Sedentary Young Men

2021 ◽  
Vol 10 (3) ◽  
pp. 412-423
Author(s):  
Ali Forutan Ghojebiglo ◽  
◽  
Marefat Siahkohian ◽  
Leila Fasihi ◽  
◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Lactate Dehydrogenase ◽  
Muscle Pain ◽  
Muscle Soreness ◽  
Pain Perception ◽  
Young Men ◽  
Repeated Measure ◽  
Delay Onset Muscle Soreness ◽  
Study Results ◽  
Significant Difference

Background and Aims Due to the concerns among trainers about relieving muscle pain as soon as possible, this study aimed to investigate the effect of eccentric retraining on muscle pain and Delay Onset Muscle Soreness (DOMS) markers in sedentary young men. Methods In this study, sixteen inactive healthy young men voluntarily and after written informed consent. Subjects were randomly divided into control (n=8) and experimental (n=8) groups. Both groups performed seventy eccentric contractions in the flexor elbow muscles with 80% of maximal repetition. Muscular pain perception, serum levels of Creatine Kinase (CK), and Lactate Dehydrogenase (LDH) indices were measured before, one, 26, 48 and 72 hours after eccentric training. Independent t-test and Repeated measure analysis variance in the significant level of P≤0.05 used for data analysis. Results The sensation of muscle pain and creatine kinase in both groups increased significantly after exercise (P≤0.05), lactate dehydrogenase level was increased in both groups. Still, this increase was not significant (P>0.05). Also, no significant difference in the CK and LDH and pain perception in the measurement stage between the two groups was observed (P>0.05). Conclusion This study results showed that retraining isn’t an essential influential variable on muscle pain and DOMS markers. However, more research needs to be done in this area.

scholarly journals Effect of Various Diluents on the Activity of Several Enzymes Present in Serum

1973 ◽  
Vol 19 (9) ◽  
pp. 1079-1080
Author(s):  
Ted W Fendley ◽  
Jane M Hochholzer ◽  
Christopher S Frings
Keyword(s):  
Alkaline Phosphatase ◽  
Creatine Kinase ◽  
Enzyme Activity ◽  
Lactate Dehydrogenase ◽  
Confidence Level ◽  
Aspartate Aminotransferase ◽  
Nacl Solution ◽  
Manual Method ◽  
Accuracy And Precision ◽  
Significant Difference

Abstract We have evaluated the effect of diluting serum with water or NaCl solution (8.5 or 9.0 g/liter) before assaying by a manual method for creatine kinase (EC 2.7.3.2), alkaline phosphatase (EC 3.1.3.1), lactate dehydrogenase (EC 1.1.1.27), and aspartate aminotransferase (EC 2.6.1.1) activity. The t test and the F test show no significant difference in the accuracy and precision of the assays at the 95% confidence level when 100 different samples were compared for each enzyme activity after use of the three diluents.

scholarly journals Comparison between old and young men for changes in makers of muscle damage following voluntary eccentric exercise of the elbow flexors

2006 ◽  
Vol 31 (3) ◽  
pp. 218-225 ◽  
Author(s):  
Andrew P Lavender ◽  
Kazunori Nosaka
Keyword(s):  
Creatine Kinase ◽  
Muscle Damage ◽  
Eccentric Exercise ◽  
Repeated Measures ◽  
Muscle Soreness ◽  
Young Men ◽  
Young Group ◽  
Creatine Kinase Activity ◽  
Isometric Strength ◽  
Elbow Flexors

This study aimed to investigate if old men were more susceptible than young men to muscle damage induced by exercise consisting of repeated-lengthening muscle actions. The responses to a bout of eccentric exercise were compared between 10 young (mean age ± SEM = 19.4 ± 0.4 y) and 10 old (70.5 ± 1.5 y) men. All subjects performed 6 sets of 5 lengthening actions of the left elbow flexors at a range of 90° from an elbow flexed (90°) to an extended (180°) position in 5 s using a dumbbell massed at 40% maximal isometric strength (MVC) at an elbow joint angle of 90°. Changes in MVC, range of motion (ROM), upper arm circumference (CIR), muscle soreness (DOMS), plasma creatine kinase activity (CK), and myoglobin (Mb) concentration over 7-10 d following exercise were compared between groups by 2-way repeated measures analysis of variance (ANOVA). Significant differences between groups were evident at baseline for ROM (significantly smaller for the older group) and CIR (significantly larger for the older group), but not for MVC and other measures. Contrary to the hypothesis, the young group showed significantly larger decreases in MVC and ROM and larger increases in circumference, DOMS, CK activity, and Mb con centration than those of the old group. These results suggest that muscle damage is not necessarily greater in old versus young men following voluntary eccentric exercise. It may be that physiological changes that occur with ageing, including a decrease in ROM, reduce damaging stress to muscles during lengthening muscle actions.Key words: ageing, maximal isometric strength, muscle soreness, creatine kinase, myoglobin.

scholarly journals Effects of Far‐Infrared Emitting Ceramic Material Clothing on Recovery After Maximal Eccentric Exercise

2019 ◽  
Vol 70 (1) ◽  
pp. 135-144
Author(s):  
Renan Felipe Hartmann Nunes ◽  
Naiandra Dittrich ◽  
Rob Duffield ◽  
Marília Cavalcante Serpa ◽  
Tiago Martins Coelho ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Lactate Dehydrogenase ◽  
Muscle Damage ◽  
Eccentric Exercise ◽  
Muscle Soreness ◽  
Far Infrared ◽  
Ceramic Materials ◽  
Voluntary Contraction ◽  
Delayed Onset Muscle Soreness ◽  
Delayed Onset

Abstract The purpose of this study was to determine whether Far-Infrared Emitting Ceramic Materials worn as Bioceramic pants would improve neuromuscular performance, biochemical and perceptual markers in healthy individuals after maximal eccentric exercise. Twenty-two moderately active men were randomized into Bioceramic (n = 11) or Placebo (n = 11) groups. To induce muscle damage, three sets of 30 maximal isokinetic eccentric contractions of the quadriceps were performed at 60°·s-1. Participants wore the bioceramic or placebo pants for 2 hours immediately following the protocol, and then again for 2 hours prior to each subsequent testing session at 24, 48 and 72 hours post. Plasma creatine kinase and lactate dehydrogenase activity, delayed-onset muscle soreness, perceived recovery status, and maximal voluntary contraction were measured pre-exercise and 2, 24, 48, and 72 hours post-exercise. Eccentric exercise induced muscle damage as evident in significant increases in delayed-onset muscle soreness at 24 - 72 hours (p < 0.05) and creatine kinase between Pre to 2, 24, 48 and 72 hours (p < 0.05). Despite the increased delayed-onset muscle soreness and creatine kinase values, no effect of Bioceramic was evident (p > 0.05). Furthermore, decreases in maximal voluntary contraction between Pre and immediately, 2, 24, 48 and 72 hours post (p < 0.05) were reported. However, the standardized difference was moderate lower for lactate dehydrogenase at 24 h (ES = 0.50), but higher at 48 h (ES = -0.58) in the Bioceramic compared to the Placebo group. Despite inducing muscle damage, the daily use of Far-Infrared Emitting Ceramic Materials clothing over 72 hours did not facilitate recovery after maximal eccentric exercise.

The effect of essential oil of rosemary on eccentric exercise-induced delayed-onset muscle soreness in non-active women

2020 ◽  
Vol 16 (2) ◽  
pp. 129-136 ◽  
Author(s):  
M. Rezaee ◽  
R. Hajiaghaee ◽  
K. Azizbeigi ◽  
S. Rahmati-Ahmadabad ◽  
M. Helalizadeh ◽  
...  
Keyword(s):  
Essential Oil ◽  
Muscle Soreness ◽  
Repeated Measure ◽  
Post Exercise ◽  
Damage Indicator ◽  
Significant Difference ◽  
Measure Analysis ◽  
Repeated Measure Analysis ◽  
Exercise Induced ◽  
Rosemary Essential Oil

Muscle soreness is a problem associated with physical activities. Recently, the medicinal herbs are strategies to prevent muscle soreness. The present study aims were to determine the effect of rosemary essential oil on the responses of lactate dehydrogenase, creatine kinase (CK), lymphocytes, neutrophils, muscle swelling (MS) and muscle pain (MP) following eccentric leg curl exercise in non-active women. 24 non-active females voluntarily participated in this study and were randomly assigned into three groups: rosemary dose 1 (RD1) (n=8; 0.25 ml), rosemary dose 2 (RD2) (n=8; 0.5 ml) and placebo (n=8; 0.5 ml olive oil). Participants in supplement groups consumed the desire amounts of rosemary essential oil every 8 h per day for 14 days. Then, the eccentric leg curl exercise was performed. The supplementation continued until 72 h after exercise. The serum variables, as well as, MS and MP were measured before, 24, 48 and 72 h after exercise. Data were analysed using repeated measure analysis of variance and P≤0.05 considered as significant. The results showed that rosemary significantly decreases CK in RD2 compared with placebo and RD1 48 h after exercise. There was no other significant difference in other serum variables. In conclusion, the present study showed a beneficial effect of rosemary on 48-h post-exercise serum CK concentration (a muscle damage indicator).

scholarly journals Neurodynamic mobilization and foam rolling improved delayed-onset muscle soreness in a healthy adult population: a randomized controlled clinical trial

PeerJ ◽  
2017 ◽  
Vol 5 ◽  
pp. e3908 ◽  
Author(s):  
Blanca Romero-Moraleda ◽  
Roy La Touche ◽  
Sergio Lerma-Lara ◽  
Raúl Ferrer-Peña ◽  
Víctor Paredes ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Muscle Soreness ◽  
Pain Perception ◽  
Rating Scale ◽  
Adult Population ◽  
Rectus Femoris ◽  
Controlled Clinical Trial ◽  
Double Blind ◽  
Maximum Voluntary Isometric Contraction ◽  
Significant Difference

Objectives Compare the immediate effects of a Neurodynamic Mobilization (NM) treatment or foam roller (FR) treatment after DOMS. Design Double blind randomised clinical trial. Setting The participants performed 100 drop jumps (5 sets of 20 repetitions, separated by 2 min rests) from a 0.5-m high box in a University biomechanics laboratory to induce muscle soreness. The participants were randomly assigned in a counter-balanced fashion to either a FR or NM treatment group. Participants Thirty-two healthy subjects (21 males and 11 females, mean age 22.6 ± 2.2 years) were randomly assigned into the NM group (n = 16) or the FR group (n = 16). Main Outcome Measures The numeric pain rating scale (NPRS; 0–10), isometric leg strength with dynamometry, surface electromyography at maximum voluntary isometric contraction (MVIC) and muscle peak activation (MPA) upon landing after a test jump were measured at baseline, 48 h after baseline before treatment, and immediately after treatment. Results Both groups showed significant reduction in NPRS scores after treatment (NM: 59%, p < .01; FR: 45%, p < .01), but no difference was found between them (p > .05). The percentage change improvement in the MVIC for the rectus femoris was the only significant difference between the groups (p < 0.05) at post-treatment. After treatment, only the FR group had a statistically significant improvement (p < 0.01) in strength compared to pre-treatment. Conclusion Our results illustrate that both treatments are effective in reducing pain perception after DOMS whereas only FR application showed differences for the MVIC in the rectus femoris and strength.

scholarly journals Evaluation of Creatine Kinase, Lactate Dehydrogenase, and Amylase Concentrations in Umbilical Blood of Preterm Infants after Long-Term Tocolysis

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Yoshiyuki Nakajima ◽  
Naoki Masaoka
Keyword(s):  
Creatine Kinase ◽  
Birth Weight ◽  
Lactate Dehydrogenase ◽  
Preterm Infants ◽  
Gestational Age ◽  
Umbilical Blood ◽  
Significant Difference ◽  
Group A ◽  
Group B

Creatine kinase (CK), lactate dehydrogenase (LDH), and amylase levels of preterm infants following long-term tocolysis in pregnant women are limited. The objective of this study was to determine if the tocolytic therapy affects CK, LDH, and amylase levels in the umbilical blood. This study included 215 preterm infants born to women treated with and without ritodrine hydrochloride. CK, LDH, and amylase levels in the umbilical blood at delivery were determined. Infants were divided according to the ritodrine tocolysis, as follows: Group A (n=91), not exposed to ritodrine; Group B (n=44), IV ritodrine for <1 week; Group C (n=80), IV ritodrine for ≥1 week. The CK concentration in cord blood of Group C (198.8±14.2 IU/L) was significantly higher in comparison with Group A (155.0±7.3 IU/L,P<0.05). There was no significant difference in LDH and amylase levels in the three groups. The CK significantly correlated with gestational age (r=0.42,P<0.01) and birth weight (r=0.38,P<0.01). LDH and amylase levels did not change with gestational age nor birth weight. In conclusion, long-term ritodrine tocolysis leads to increased umbilical blood CK level.

Inactivated Serum vs. Saline as a Diluent in Some Serum Enzyme Assays

1975 ◽  
Vol 21 (1) ◽  
pp. 154-155
Author(s):  
Ted W Fendley ◽  
Christopher S Frings
Keyword(s):  
Alkaline Phosphatase ◽  
Creatine Kinase ◽  
Lactate Dehydrogenase ◽  
Enzyme Assays ◽  
Nacl Solution ◽  
Serum Enzyme ◽  
End Point ◽  
Accuracy And Precision ◽  
Significant Difference ◽  
Good For

Abstract In assays of creatine kinase (EC 2.7.3.2), alkaline phosphatase (EC 3.1.3.1), lactate dehydrogenase (EC 1.1.1.27), or asparate aminotransferase (EC 2.6.1.1) activities by certain end-point methods, we found no significant difference in the accuracy and precision of the results when serum was diluted with heat-inactivated pooled serum or NaCl solution (8.5 g/liter). For creatine kinase, asparate aminotransferase, and alkaline phosphatase, correlations were good for the two diluents, but poor in the case of lactate dehydrogenase.

scholarly journals Comparison of Acellular Solutions for Ex-situ Perfusion of Amputated Limbs

2020 ◽  
Vol 185 (11-12) ◽  
pp. e2004-e2012
Author(s):  
Valentin Haug ◽  
Branislav Kollar ◽  
Yori Endo ◽  
Nikita Kadakia ◽  
Anamika Veeramani ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Lactate Dehydrogenase ◽  
Cold Storage ◽  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Ex Situ ◽  
Blood Gas ◽  
Promising Alternative ◽  
Significant Difference ◽  
Over Time

Abstract Introduction Hypothermic ex-situ machine perfusion (MP) has been shown to be a promising alternative to static cold storage (SCS) for preservation of solid organs for transplantation and vascularized composite allotransplantation. Perfusion with blood-based perfusion solutions in austere environments is problematic due to their need for appropriate storage and short shelf life, making it impractical for military and emergency use. Acellular perfusion has been shown to be effective, but the ideal perfusate solution for MP of amputated limbs is yet to be determined. The purpose of this study is to evaluate the efficacy of alternative perfusate solutions, such as dextran-enriched Phoxilium, Steen, and Phoxilium in ex-vivo hypothermic MP of amputated limbs in a porcine model. Materials and methods Amputated forelimbs from Yorkshire pigs (n = 8) were preserved either in SCS (n = 2) at 4°C for 12 hours or machine-perfused at 10°C for 12 hours with oxygenated perfusion solutions (n = 6) at a constant flow rate. The perfusates used include modified Steen-solution, Phoxilium (PHOX), or Phoxilium enriched with dextran-40 (PHODEX). The perfusate was exchanged after 1 and 6 hours of perfusion. Machine data were recorded continuously. Perfusate samples for clinical chemistry, blood gas analysis, and muscle biopsies were procured at specific timepoints and subsequently analyzed. In this semi in-vivo study, limb replantation has not been performed. Results After amputation, every limb was successfully transferred and connected to our perfusion device. The mean total ischemia time was 77.5 ± 5.24 minutes. The temperature of the perfusion solution was maintained at 10.18 ± 2.01°C, and perfusion pressure at 24.48 ± 10.72 mmHg. Limb weight increased by 3% in the SCS group, 36% in the PHODEX group, 25% in the Steen group, and 58% in the PHOX group after 12 hours. This increase was significant in the PHOX group compared with the SCS group. All perfusion groups showed a pressure increase of 10.99 mmHg over time due to edema. The levels of HIF-1a decreased over time in all groups except the Steen and the PHODEX group. The biomarkers of muscle injury in the perfusate samples, such as creatine kinase and lactate-dehydrogenase, showed a significant difference between groups, with highest values in the PHODEX group. No significant differences were found in the results of the blood gas analysis. Conclusion With the exception of significantly higher levels of creatine kinase and lactate dehydrogenase, MP with dextran-enriched Phoxilium provides similar results as that of the commercially available perfusates such as Steen, without the need for cold storage, and at circa 5% of the cost of the Steen solution. Further large-scale replantation studies are necessary to evaluate the efficacy of dextran-enriched Phoxilium as an alternate perfusate solution.

scholarly journals Comparative evaluation of soft and hard splints in treatment of clenching disorder

2021 ◽  
Author(s):  
Majid Sahebi ◽  
Mohammadreza Hajimahmoudi ◽  
Faezeh Atri
Keyword(s):  
Muscle Pain ◽  
Mouth Opening ◽  
Repeated Measure ◽  
Masticatory Muscle ◽  
Delivery Time ◽  
Significance Level ◽  
Measure Anova ◽  
Significant Difference ◽  
Masticatory Muscle Pain ◽  
Maximum Opening

Introduction: The aim of this study was to compare the efficiency of soft and hard splints in treating patients with clenching. Materials and Methods: In this clinical study, 26 patients with clenching disorder random- ly divided to two equal group of treatment: hard and soft splint. The amount of masticatory muscle pain and maximum mouth opening were measured at the delivery time and 3, 6, 9, and 12 weeks later by a blind examiner. Data were analyzed by independent T and repeated measure ANOVA tests with significance level of p=0.05. Results: Hard and soft splints were resulted in significant reduction of masticatory muscle pain (hard: P<0.001, Soft: p<0.001) and increase in maximum opening (hard P<0.001, Soft p<0.003), but there was no significant difference between them in pain relieving (P=0.848) and maximum opening (P=0.622). Conclusion: This study showed that efficacy of hard and soft splints in treating patients with clenching is same.

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