Synthesis of an Oxacepham derivative from 1,2-O-Cyclohexylidene-α-DXylofuranose

Thy Thi Mong Lu; Danh Thanh Tong

doi:10.32508/stdj.v18i3.877

Synthesis of an Oxacepham derivative from 1,2-O-Cyclohexylidene-α-DXylofuranose

Science and Technology Development Journal ◽

10.32508/stdj.v18i3.877 ◽

2015 ◽

Vol 18 (3) ◽

pp. 87-95

Author(s):

Thy Thi Mong Lu ◽

Danh Thanh Tong

Keyword(s):

Vinyl Ether ◽

Bacterial Infections ◽

Main Tool ◽

Special Role ◽

Active Compounds ◽

Chlorosulfonyl Isocyanate

Carbohydrates have gained much attention as cheap chiral starting materials in stereocontrolled target oriented synthesis. β-lactam antibiotics still remain the main tool against bacterial infections but the search for new active compounds has not been the aim of reported investigations. Synthesis of β-lactam antibiotics from carbohydrate precursors played a special role owing to the importance of these classes of compounds in modern chemotherapy. In this report, we carried out this subject to synthesize β-lactam derivative (oxacepham) via [2 + 2] cycloaddition of chlorosulfonyl isocyanate (CSI) to vinyl ether derived from carbohydrate (α-D-glucose).

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Prooxidant-antioxidant homeostasis and reproductive capacity of boars under the influence of copper citrate

The Animal Biology ◽

10.15407/animbiol23.02.012 ◽

2021 ◽

Vol 23 (2) ◽

pp. 12-18

Author(s):

A. S. Siabro ◽

Keyword(s):

Live Weight ◽

Reproductive Capacity ◽

High Fertility ◽

Special Role ◽

Diene Conjugates ◽

Active Compounds ◽

Litter Weight ◽

Fertilizing Ability ◽

Peroxidation Processes

Peroxide oxidation processes play a leading role in ensuring the motility, survival and fertilizing ability of sperm. A special role is given to limiting antioxidants (vitamins, amino acids, microelements). Therefore, the development of standardized feeding programs to provide antioxidant nutrition is one of the effective methods of reproductive biotechnology. The aim of the study was to determine the effect of copper citrate on the quality of sperm production and the formation of prooxidant-antioxidant homeostasis in sperm of boars. The experiment used adult boars of a large white breed, analogs in age, live weight and quality of sperm products. Experimental groups were fed copper citrate above the norm by 10% and 20%. It has been determined that feeding combined feed to boars with the addition of this compound in an amount of 10% above norm probably increases the weight of ejaculate by 12.5% (P<0.05), the sperm motility and survival by 6.5% (P<0.01) and 13.5% (P<0.001), respectively. Such changes in sperm occur against the background of an increase in SOD activity by 80.6% (P<0.05), a decrease in catalase by 43.5% (P<0.05), a slowing down of peroxidation processes — a decrease in diene conjugates and TBA-active compounds. The additional introduction to the diet of copper citrate by 20% more than normal increases the concentration of spermatozoa by 13.2% (P<0.01), the number of live spermatozoa by 20.7% (P<0,01), with a simultaneous decrease in their survival, due to the acceleration of peroxidation processes — an increase in the content of diene conjugates, TBA-active compounds and DAA and a decrease in reduced glutathione. It has been found out that the fertilizing ability of sperm significantly depended on the amount of fed microelement. Sows inseminated with sperm of boars receiving copper supplement in the diet by 10%, had higher fertility rates by 7.1%, multifertility by 3.6%, and a litter weight at weaning by 8.8%. The additional administration of copper citrate reduced the fertility of sperm by 20%, as the fertility rate of sows of III group was the lowest and was 7.7% and 14.3% lower compared to I and II groups. A similar trend occurred in terms of high fertility, a litter weight at birth and weaning. Therefore, the additional feeding of a small amount of copper has a positive effect on the functional activity of sperm and the processes of normal fertilization, growth and development of embryos and newborn piglets by optimizing the formation of prooxidant-antioxidant homeostasis.

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Technology for Solving the Problems Related To the Implementation of the Concept of Preserving Capital in Accounting and Statistics

International Journal of Recent Technology and Engineering - 2 ◽

10.35940/ijrte.c4020.098319 ◽

2019 ◽

Vol 8 (3) ◽

pp. 789-792 ◽

Cited By ~ 5

Keyword(s):

Discount Rate ◽

Theory Development ◽

Main Tool ◽

Financial Statements ◽

Cash Flows ◽

Economic Life ◽

International Standards ◽

Special Role ◽

Present Value ◽

Specific Interpretation

At the present stage of economic theory development, a special role as a comprehensive indicator of the efficiency of activity is acquired by the current cost of the organization’s capital. The definition of the value of an asset was first explained by Fisher “The cost of a capital asset equals the sum of the present value of all future cash flow receipts” [17]. The concept of the current value of invested capital is the main tool for increasing the transparency of financial statements and a component of the concept of value and capital. In his work “The Nature of Capital and Income,” the American economist Fisher stated that "The theory of capital is that the value of an asset is equal to future cash receipts, reduced to present value based on the appropriate discount rate ”[1]. As for John Barr William, a well-known investor wrote in his book “The Theory of Investment Value” that “the value of any company is determined by incoming and outgoing cash flows, adjusted at a discount rate” [5]. The specific interpretation of capital by international standards largely determines the methodology for accounting for specific facts of economic life, as well as the approach to providing the financial position of an organization in its financial statements

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LINGUISTICS OF MODERN GEORGIAN MEDIA

Vectors of Social Sciences ◽

10.51895/vss1/zakarashvili ◽

2021 ◽

Vol 1 (1) ◽

Author(s):

Tinatin Zakarashvili

Keyword(s):

Mass Media ◽

Digital Media ◽

Large Scale ◽

Negative Impact ◽

Cognitive Activity ◽

Main Tool ◽

Scientific Article ◽

Special Role ◽

The Media ◽

Modern Mass

Modern mass media, as an important means of informing the public, determines people’s consciousness, shapes their interests and determines the mood. It has also successfully incorporated the role of an educator from the very beginning. Thus, the media linguistics plays a special role in spreading the native Georgian language, as well as in raising the literacy rate of the population. Language is the main tool to guide human cognitive activity. Although, there are many examples of media trying to comply with linguistic norms, modern broadcasting fails to maintain proper Georgian; digital media being particularly full of many linguistic and stylistic errors. It should also be noted that electronic media is the only source of information for many, especially the young people. Given the high social importance, journalists should be careful with dealing with the language. The development and transformation process of mass media in the global information space is not only indirectly but also directly reflected, especially in the formation of the Internet media linguistics. The current social and political changes in the country have also affected the process of language deformation. The scientific article deals with the influence of media language on the linguistic features of the Georgian society. It discusses the problematic issues of modern publicist thinking, focusing on the linguistic distortions that modern journalists are characterized with. The speech problem of media representatives is topical, complex and large-scale. Their speeches are the basis of the communicative interaction of the society, contribute to the linguistic influence, national identity, mutual understanding of people, perception of the world. The media significantly influences the value system, mentality and literary norms used in any society. Violation of literary norms, which is observed in modern Georgian media, has a negative impact on the audience and the level of literary competence of the speakers.

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