scholarly journals RESEARCH FOR THE ESTABLISHMENT AND SOLUTION MATHEMATICAL MODEL OF HEAT AND MASS TRANSFER AT THE SAME TIME IN PROCESSING FREEZE - DRYING

2009 ◽  
Vol 12 (8) ◽  
pp. 67-80
Author(s):  
Dung Tan Nguyen ◽  
Dung Van Trinh ◽  
Bao Duc Tran

When applied technology Freeze - Drying in preserving foods had economy value, it seems that establishment and solution mathematical model heat and mass transfer at the same time in conditional processing freeze - drying is very important problem. From that point it is basis of science to determine regime technology Freeze - Drying. In this article, we will publish result research to set up and solve mathematical model heat and mass transfer at the same time of cylinder form in conditional freeze - drying. Result research will apply for preserving fishery foods crustacean group (PENAEUS MONODON, PENAEUS MERGUIENSIS, PENAEUS VANNAMEI) has economy value.

2014 ◽  
Vol 989-994 ◽  
pp. 3100-3104
Author(s):  
Rui Hang Zhang ◽  
Zi Ye Wang ◽  
Run Ping Niu

TA mathematical model describing heat and mass transfer performance of packed-type parallel flow dehumidifier was set up. The numerical solution of differential equations was derived. Taking the heat and mass transfer coefficients obtained by experiments as the input parameters of the model, the impact of solution inlet parameters on outlet parameter of air was described. The simulation results indicated that the mathematical model could be used to predict the performance of liquid dehumidification. The results showed that the mathematical model can be of great value in the design and improvement of dehumidifier.


2007 ◽  
Vol 3 (2) ◽  
pp. 192-196
Author(s):  
Hua Li ◽  
Lihua Li ◽  
Xingli Jiao ◽  
Xueli Qin

The freeze-drying process is a complex heat and mass transfer process virtually. The drying process of freeze-drying is not only the key stage which decides the success of freeze-drying, but also the most difficult stage to control. There are lots of papers about heat and mass transfer in vacuum freeze drying at home and abroad. The present status of research on heat and mass transfer during vacuum freeze drying in the secondary drying is summed up and analyzed, and the trend of research in this field is discussed in this paper.


2011 ◽  
Vol 383-390 ◽  
pp. 6568-6573 ◽  
Author(s):  
Run Ping Niu

The performance of air dehumidifier using LiCl solution as the Liquid desiccant was studied with numerical methods. A mathematical model describing heat and mass transfer performance of air dehumidifierwas set up. The numerical solution of differential equations were derived. Taking the heat and mass transfer coefficients obtained by experiments as the input parameters of the model,the parameter distribution of air and solution was described. The simulation results corresponds very well to experimental data. Simulation results indicated that the mathematical model could be used to predict the performance of air dehumidifier. The results showed that the mathematical model can be of great value in the design and improvement of air dehumidifier.


2012 ◽  
Vol 2012 ◽  
pp. 1-16 ◽  
Author(s):  
Zou Huifen ◽  
Ye Sheng ◽  
Wang Dexi ◽  
Li Huixing ◽  
Cao Xiaozhen ◽  
...  

Cornea is the important apparatus of organism, which has complex cell structure. Heat and mass transfer and thermal parameters during vacuum freeze-drying of keeping corneal activity are studied. The freeze-drying cornea experiments were operated in the homemade vacuum freeze dryer. Pressure of the freeze-drying box was about 50 Pa and temperature was about −10°C by controlled, and operating like this could guarantee survival ratio of the corneal endothelium over the grafting normal. Theory analyzing of corneal freeze-drying, mathematical model of describing heat and mass transfer during vacuum freeze-drying of cornea was established. The analogy computation for the freeze-drying of cornea was made by using finite-element computational software. When pressure of the freeze-drying box was about 50 Pa and temperature was about −10°C, time of double-side drying was 170 min. In this paper, a moving-grid finite-element method was used. The sublimation interface was tracked continuously. The finite-element mesh is moved continuously such that the interface position always coincides with an element node. Computational precision was guaranteed. The computational results were agreed with the experimental results. It proved that the mathematical model was reasonable. The finite-element software is adapted for calculating the heat and mass transfer of corneal freeze-drying.


Author(s):  
Bernadette Scutellà ◽  
Ioan Cristian Trelea ◽  
Erwan Bourlés ◽  
Fernanda Fonseca ◽  
Stephanie Passot

Freeze-drying is a dehydration method suitable for the stabilization of heat-labile pharmaceutical products, such as vaccines. Due to the vial-to-vial variability of heat and mass transfer during the process, the value of the critical process parameters (e.g., product temperature, sublimation rate) may be different between vials and batches often present significant product quality heterogeneity. The aim of this work was the development of a dynamic, multi-vial mathematical model making it possible to predict risk of failure of the process, defined as the percentage of vials potentially rejected by quality inspection. This tool could assist the design of freeze-drying cycle. Keywords: lyophilization; vaccines; heat and mass transfer; mathematical modeling; design space  


1993 ◽  
Vol 253 (-1) ◽  
pp. 341 ◽  
Author(s):  
G. I. Barenblatt ◽  
M. Bertsch ◽  
R. Dal Passo ◽  
V. M. Prostokishin ◽  
M. Ughi

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