Computation of fission product deposition in aerosols

2019 ◽  
Author(s):  
◽  
Nathan Edward White
Keyword(s):  
Fission Product ◽  
Mean Free Path ◽  
Dust Particles ◽  
University Of Missouri ◽  
Transport Regime ◽  
Surface Areas ◽  
Monte Carlo Computation ◽  
Wide Range ◽  
The University ◽  
The Continuum

[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] High-temperature gas-cooled reactors (HTGRs) generate carbonaceous dust during both normal operations and accidents. The dust particles can be both highly irregular and porous and have exceptionally large surface areas, making dust-facilitated fission product (FP) transport a major factor in the computation of the nuclear source term. Since the FP interactions with the dust can occur while the dust is on a surface as well as in suspension, there is a need to obtain computational and experimental results for both situations. Since the particle sizes of interest span a wide range, from nanometers to microns, and are porous with various pathways for FP interactions to occur, these computations need to include not only the continuum regime, but the transport regime as well where the particle (or pore) size is comparable to the vapor (FP) mean free path. The focus of this dissertation is on Monte Carlo computation of the condensation rate on chainlike particles and particle agglomerates in the transport regime, towards a better understanding of how aerosol geometry affects mass transport on those particles.

TEM study of boron additions to cobalt aluminide

1988 ◽  
Vol 46 ◽  
pp. 546-547
Author(s):  
Gerald B. Feldewerth
Keyword(s):  
High Temperature ◽  
Turbine Engines ◽  
Major Drawback ◽  
University Of Missouri ◽  
Specific Strength ◽  
Aerospace Applications ◽  
Wide Range ◽  
Ordered Alloys ◽  
The University ◽  
Very High

In recent years an increasing emphasis has been placed on the study of high temperature intermetallic compounds for possible aerospace applications. One group of interest is the B2 aiuminides. This group of intermetaliics has a very high melting temperature, good high temperature, and excellent specific strength. These qualities make it a candidate for applications such as turbine engines. The B2 aiuminides exist over a wide range of compositions and also have a large solubility for third element substitutional additions, which may allow alloying additions to overcome their major drawback, their brittle nature.One B2 aluminide currently being studied is cobalt aluminide. Optical microscopy of CoAl alloys produced at the University of Missouri-Rolla showed a dramatic decrease in the grain size which affects the yield strength and flow stress of long range ordered alloys, and a change in the grain shape with the addition of 0.5 % boron.

The influence of mRNA secondary structures on ribosome conformational dynamics

2016 ◽  
Author(s):  
◽  
Bassem Shebl
Keyword(s):  
Protein Synthesis ◽  
Conformational Dynamics ◽  
Bacterial Cells ◽  
University Of Missouri ◽  
Novel Drugs ◽  
Wide Range ◽  
Complicated Process ◽  
One Step ◽  
The University ◽  
Control Protein

[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Synthesizing proteins in the cell is a critical aspect of life. Protein synthesis is a complicated process and involve highly functional machines at a molecular level. The ribosome is the molecular machine that translate coded sequences of nucleic acids into functional proteins. Understanding how ribosomes function is key to understanding protein synthesis / translation. We focus our work on ribosomes from bacterial cells. This allows us to study much simpler systems and extrapolate our knowledge to higher levels. One key challenge in the field is to be able to isolate a high quantity of good and active ribosomes out of the cell to study it in a controlled environment. Classically known methods involve extensive resources, high technical expertise, and a week of preparation. We developed a one-step protocol to purify ribosomes that are more active than the ones purified from classical methods. This developed technique saves time and money and results in much higher amounts of product. This approach also makes the technique approachable to a wider community of scientists and researchers. The same methodology could be applied towards purifying other molecular machines in the cells. Using these ribosomes, we wanted to investigate how the ribosomes function in cells when faced with specific signals. These signals are utilized by the cells to control protein synthesis. However, in dome diseased cells and for some viruses, normal protein synthesis is overridden by the invaders to produce faulty proteins that could result in a wide range of diseases such as Alzheimer and others. In this study, we investigated how the ribosome functions in the presence of such signals and how close do they need to be to the ribosome to affect protein synthesis. This allows us to design drugs to mimic or inhibit such changes thus fixing faulty protein production or sometimes induce it to inhibit protein synthesis in bacterial cells and as such designing and producing novel drugs.

Big gorgeous jazz machine

2018 ◽  
Author(s):  
◽  
Nick Francis Potter
Keyword(s):  
Twentieth Century ◽  
Contemporary Art ◽  
University Of Missouri ◽  
Avant Garde ◽  
Introductory Essay ◽  
Cultural Legitimacy ◽  
Wide Range ◽  
Specific Strain ◽  
Formal Relationship ◽  
The University

[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] This manuscript considers the influence of twentieth-century avant-garde literature and painting in contemporary art comics, particularly the growing sub-genre of comics poetry. The introduction lays a historical groundwork for this specific strain of comics, including antecedent works and a consideration for how the genre fits into the comics medium's longstanding struggle for cultural legitimacy. Further, the introductory essay examines how the wide range of comics that fit under the umbrella of comics poetry remediate modernist practices in poetry and painting, foregrounding simultaneity and materiality over transparency and narrative. This introduction considers seminal works in the field, including Warren Craghead's How to be Everywhere (2007), which reworks the calligrammes of Apollinaire, and Erin Curry's Songs of the Sea (2016), directly inspired by Cy Twombly's series of paintings by the same name. In addition to analyzing these comics, the paper considers how these works have been utilized by comics critics (Baetens, Gronesteen, Bennett, Badman) in revising and expanding critical frameworks in comics studies and developing an artist-critic relationship that closely mirrors those documented between the modernist avant-garde and the semiotic theory of Saussure early in the twentieth century (Drucker). The subsequent manuscript follow exhibits a collection of comics works that maintain a formal relationship with those discussed in the introduction.

Synthesis of exo-affinity labeling agents of protein tyrosine phosphatase non-receptor type 1

2015 ◽  
Author(s):  
◽  
Roman Hillebrand
Keyword(s):  
Protein Tyrosine Phosphatase ◽  
Tyrosine Phosphatase ◽  
Allyl Isothiocyanate ◽  
Negative Regulator ◽  
Cancer Drug ◽  
University Of Missouri ◽  
Protein Tyrosine ◽  
Wide Range ◽  
The University ◽  
Derivatives Of

[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Protein-tyrosine phosphatase 1B (PTP1B) is a negative regulator in the insulin signaling cascade. A lot of research has focused on inhibiting PTP1B but with no success. Only one drug is currently in phase II clinical trials. We have developed a synthetic protocol to create a library of molecules that target residues outside the active site and covalently bind to the enzyme via close proximity alkylation. These molecules will be analyzed towards inactivation/inhibition capabilities. Tirapazamine is a hypoxia selective anti-cancer drug. New derivatives of Tirapazamine are sought after. We have analyzed and optimized Suzuki-Miyaura and Buchwald-Hartwig couplings reactions towards new derivatives of Tirapazamine. Allyl isothiocyanate (AITC) is a phytochemical that can be found in cruciferous vegetables and has received interest due to beneficial health effects. During our analyses of AITC towards inactivation of PTP1B we noticed the surprising absence of the isothiocyanate carbon in 13C NMR spectra. Calculations show that the absence is due to the facile change of the N-hybridization in the wide range of 120 less than 180 bond angles in AITC.

scholarly journals Inversion of the transverse force on a spinning sphere moving in a rarefied gas

2021 ◽  
Vol 933 ◽  
Author(s):  
Satoshi Taguchi ◽  
Tetsuro Tsuji
Keyword(s):  
Boltzmann Equation ◽  
Knudsen Number ◽  
Rarefied Gas ◽  
Mean Free Path ◽  
Transverse Force ◽  
Surface Velocity ◽  
Translational Velocity ◽  
The Boltzmann Equation ◽  
Wide Range ◽  
The Continuum

The flow around a spinning sphere moving in a rarefied gas is considered in the following situation: (i) the translational velocity of the sphere is small (i.e. the Mach number is small); (ii) the Knudsen number, the ratio of the molecular mean free path to the sphere radius, is of the order of unity (the case with small Knudsen numbers is also discussed); and (iii) the ratio between the equatorial surface velocity and the translational velocity of the sphere is of the order of unity. The behaviour of the gas, particularly the transverse force acting on the sphere, is investigated through an asymptotic analysis of the Boltzmann equation for small Mach numbers. It is shown that the transverse force is expressed as $\boldsymbol{F}_L = {\rm \pi}\rho a^3 (\boldsymbol{\varOmega} \times \boldsymbol{v}) \bar{h}_L$ , where $\rho$ is the density of the surrounding gas, a is the radius of the sphere, $\boldsymbol {\varOmega }$ is its angular velocity, $\boldsymbol {v}$ is its velocity and $\bar {h}_L$ is a numerical factor that depends on the Knudsen number. Then, $\bar {h}_L$ is obtained numerically based on the Bhatnagar–Gross–Krook model of the Boltzmann equation for a wide range of Knudsen number. It is shown that $\bar {h}_L$ varies with the Knudsen number monotonically from 1 (the continuum limit) to $-\tfrac {2}{3}$ (the free molecular limit), vanishing at an intermediate Knudsen number. The present analysis is intended to clarify the transition of the transverse force, which is previously known to have different signs in the continuum and the free molecular limits.

The missional ground : Indians, missionaries, and the forging of the antebellum frontiers

2016 ◽  
Author(s):  
◽  
Joshua M. Rice
Keyword(s):  
American Culture ◽  
Religious Diversity ◽  
Middle Ground ◽  
Colonial Power ◽  
University Of Missouri ◽  
Internal Conflicts ◽  
Wide Range ◽  
Class Background ◽  
American Hegemony ◽  
The University

[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] When historians search for Native agency, they often look in places where indigenous and colonial forces were evenly matched, as in Richard White's "middle ground." Implicitly, Indian agency mostly disappeared after colonial power triumphed. Critically, this model omits one faction from the antebellum frontier story: missionaries. In building their stations on the frontier, missionaries opened new zones for indigenous action, and often resisted or tempered the colonial forces bearing down on their Indian charges. This space that missionaries created was under American hegemony, but preceded the arrival of white settlement or US forces en masse. Hence, missionaries made a place that was not quite as open as the middle ground, but nonetheless hosted a wide range of social, cultural, linguistic, ethnic, and religious diversity. I call this zone the missional ground because the fluidity and Native agency in this space was squelched once the missionaries left, and troops and settlers arrived. The missional ground was consequently fragile, and required a precise balancing of missionaries, settlers, agents, diverse Indian groups, and all their interrelations. This means that the missional ground was also deeply contextual: the personality, theology, assumptions about gender and race, denomination, and class background of a missionary could make or break his mission. Hence, the missional ground not only supported Indian agency, but served as a crucible where American culture, religion, politics, and internal conflicts all boiled over.

Comparison of the relative comparator and k0 neutron activation analysis techniques for the determination of trace-element concentrations in pyrite

2012 ◽  
Vol 76 (5) ◽  
pp. 1229-1245 ◽  
Author(s):  
O. D. Osborne ◽  
A. Pring ◽  
R. S. Popelka-Filcoff ◽  
J. W. Bennett ◽  
A. Stopic ◽  
...  
Keyword(s):  
Neutron Activation Analysis ◽  
Activation Analysis ◽  
Neutron Activation ◽  
Trace Element ◽  
Published Data ◽  
Paired Data ◽  
University Of Missouri ◽  
Significance Level ◽  
Wide Range ◽  
The University

AbstractThirty pyrite samples from a wide range of localities were analysed using relative comparator and k0 neutron activation analysis (NAA) techniques at the University of Missouri Research Reactor, Columbia, Missouri, USA (MURR) and the Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW, Australia (ANSTO), respectively. Statistical analyses of the trace-element data produced by the two methods showed a generally good correlation, with the majority of elemental concentrations of paired data reported by MURR and ANSTO being indistinguishable at a 0.05 significance level. Trace-element analyses of pyrite from Navajún in Spain by both techniques compare well with published data. There is evidence for contamination by Al, Na and Ti in one set of samples, this is likely to have been introduced by contact with a plastic used in sample preparation.

MARS — Its Tenth Anniversary of Operation and its Future

1980 ◽  
Vol 19 (03) ◽  
pp. 125-132
Author(s):  
G. S. Lodwick ◽  
C. R. Wickizer ◽  
E. Dickhaus
Keyword(s):  
Conceptual Development ◽  
Administrative Support ◽  
Final Section ◽  
Economic Benefits ◽  
Hospital Environment ◽  
Computer Scientist ◽  
University Of Missouri ◽  
Complete Bibliography ◽  
The University ◽  
Economic Considerations

The Missouri Automated Radiology System recently passed its tenth year of clinical operation at the University of Missouri. This article presents the views of a radiologist who has been instrumental in the conceptual development and administrative support of MARS for most of this period, an economist who evaluated MARS from 1972 to 1974 as part of her doctoral dissertation, and a computer scientist who has worked for two years in the development of a Standard MUMPS version of MARS. The first section provides a historical perspective. The second deals with economic considerations of the present MARS system, and suggests those improvements which offer the greatest economic benefits. The final section discusses the new approaches employed in the latest version of MARS, as well as areas for further application in the overall radiology and hospital environment. A complete bibliography on MARS is provided for further reading.

Biodiversity in Vegetation and Ecosystems»: symposium on the occasion of the retirement of Prof. Dr. Fred J.A. Daniels (Munster, Germany, July 11, 2008)

2008 ◽  
pp. 123-124
Author(s):  
N. V. Matveyeva
Keyword(s):  
Wide Range ◽  
65Th Anniversary ◽  
The University

July 2008 in Münster (Germany) hosted a Symposium on the occasion of the 65th anniversary of Professor of the University of this city, Fred Daniels (Frederikus Josephus Alphonsus Daniëls). The title of this Symposium «Biodiversity in Vegetation and Ecosystems» reflected the wide range of interests of the celebrant.

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