A structural model of organization - and clinician-specific factors that predict standardized measure use among child and adolescent clinicians

2008 ◽  
Author(s):  
Jonathan R. Cook
2013 ◽  
Vol 44 (16) ◽  
pp. 3421-3433 ◽  
Author(s):  
M. A. Landolt ◽  
E. Ystrom ◽  
K. Stene-Larsen ◽  
H. Holmstrøm ◽  
M. E. Vollrath

Background.A congenital heart defect (CHD) can increase the risk of mental health problems in affected children and their parents. The extent to which risk factors for these problems are shared in families or are specific to the individual family member is unclear.Method.Prospective data from the Norwegian Mother and Child Cohort Study (MoBa; n = 93 009) were linked with a nationwide CHD registry, and 408 children with CHD were identified. Mothers' reports on child internalizing problems and their own distress were assessed by questionnaires at child ages 6, 18 and 36 months. A structural model was applied to distinguish between familial (shared) factors and individual-specific factors for mental health problems.Results.CHD was a substantial risk factor for problems in children and their mothers at all time points. CHD contributed on average 31% and 39% to the variance in children's and mothers' problems respectively. Both shared familial and individual-specific factors unique to CHD families contributed to risk for mental health problems. Whereas individual-specific risk factors contributed to the stability of problems in mothers, the effect of these factors lasted only a short time in children. Mutual influences over time were found between the mother's and the child's mental health at 18 and 36 months.Conclusions.The burden of CHD in a child is shared between family members but is also specific to the individual. This study points to a need for both an individual and a family-based approach to provide psychological support to children with CHD and their parents.


2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Gulden Gumusburun Ayalp ◽  
Ilhami Ay

PurposePrefabricated construction technology enables relatively faster and easier construction of building structures at a lower project cost, providing improved quality control with minimal material waste. Despite the advantages of prefabricated construction systems, they are not extensively used in Turkey because of specific yet largely undefined challenges. Therefore, the purpose of this study aims to determine the factors currently affecting the extensive use of prefabricated construction systems in Turkey.Design/methodology/approachThe reasons for such systems not being used extensively in Turkey were examined using responses to a questionnaire distributed amongst architects working at design firms, prefabricated-building manufacturers and contractors. The obtained survey data were statistically analysed using the SPSS 22 and LISREL 8.7 software to rank the severity of the identified challenges and determine the most critical factors.FindingsEight critical factors groups affecting the use of prefabricated construction systems and their associated factors were identified according the responses provided by the participants. Potential solutions and recommendations were proposed based on these factor groups that are expected facilitate the implementation of prefabricated construction systems in Turkey.Originality/valueLittle previous research has provided insight into the specific factors limiting the use of prefabricated construction systems. This study accordingly approaches the subject considering all phases of prefabricated construction systems and presents a structural model of the factors obtained by a confirmatory factor analysis for application to expand the use of prefabricated construction systems.


Author(s):  
Linda C. Sawyer

Recent liquid crystalline polymer (LCP) research has sought to define structure-property relationships of these complex new materials. The two major types of LCPs, thermotropic and lyotropic LCPs, both exhibit effects of process history on the microstructure frozen into the solid state. The high mechanical anisotropy of the molecules favors formation of complex structures. Microscopy has been used to develop an understanding of these microstructures and to describe them in a fundamental structural model. Preparation methods used include microtomy, etching, fracture and sonication for study by optical and electron microscopy techniques, which have been described for polymers. The model accounts for the macrostructures and microstructures observed in highly oriented fibers and films.Rod-like liquid crystalline polymers produce oriented materials because they have extended chain structures in the solid state. These polymers have found application as high modulus fibers and films with unique properties due to the formation of ordered solutions (lyotropic) or melts (thermotropic) which transform easily into highly oriented, extended chain structures in the solid state.


Author(s):  
U. Aebi ◽  
E.C. Glavaris ◽  
R. Eichner

Five different classes of intermediate-sized filaments (IFs) have been identified in differentiated eukaryotic cells: vimentin in mesenchymal cells, desmin in muscle cells, neurofilaments in nerve cells, glial filaments in glial cells and keratin filaments in epithelial cells. Despite their tissue specificity, all IFs share several common attributes, including immunological crossreactivity, similar morphology (e.g. about 10 nm diameter - hence ‘10-nm filaments’) and the ability to reassemble in vitro from denatured subunits into filaments virtually indistinguishable from those observed in vivo. Further more, despite their proteinchemical heterogeneity (their MWs range from 40 kDa to 200 kDa and their isoelectric points from about 5 to 8), protein and cDNA sequencing of several IF polypeptides (for refs, see 1,2) have provided the framework for a common structural model of all IF subunits.


Author(s):  
Y.G. Wang ◽  
H.Q. Ye ◽  
K.H. Kuo

A synthetic compound Ca4Al6SO16 (usually abbreviated as C4A3S) obtained by mixing CaO, A12O3 and CaSO4 powders and finally sintered at 1380°C is a cement with excellent hydraulicity and greatly expanding in application. It is hydralysed rapidly by water to form predominatly calcium aluminate hydrates and therefore unlikly to occur naturally, although structurally it may be regarded as an end member of the sodalite-hauynite series of naturally occuring minerals. C4A3S has a cubic structure with ao=9.19Å and space group . Fig.1 is the projection viewed down axis, in which there are two sets of 8C position in , namely CaI and CaII, occupied by the calcium atoms, respectively, and the ratio of occupations in these two sets of positions is about 3:1. This suggests that the calcium atoms can freely occupy these sites in various degrees and usually they almost locates on the CaI positions. A through-focus series of the lattice images were found in good agreement with the simulated ones. Each bright spot in the image taken at Scherzer defocus correspounds to a colunm of sulphur atom in the structural model (Fig.1).


Author(s):  
Jan-Olov Bovin ◽  
Osamu Terasaki ◽  
Jan-Olle Malm ◽  
Sven Lidin ◽  
Sten Andersson

High resolution transmission electron microscopy (HRTEM) is playing an important role in identifying the new icosahedral phases. The selected area diffraction patterns of quasi crystals, recorded with an aperture of the radius of many thousands of Ångströms, consist of dense arrays of well defined sharp spots with five fold dilatation symmetry which makes the interpretation of the diffraction process and the resulting images different from those invoked for usual crystals. The atomic structure of the quasi crystals is not established even if several models are proposed. The correct structure model must of course explain the electron diffraction patterns with 5-, 3- and 2-fold symmetry for the phases but it is also important that the HRTEM images of the alloys match the computer simulated images from the model. We have studied quasi crystals of the alloy Al65Cu20Fe15. The electron microscopes used to obtain high resolution electro micrographs and electron diffraction patterns (EDP) were a (S)TEM JEM-2000FX equipped with EDS and PEELS showing a structural resolution of 2.7 Å and a IVEM JEM-4000EX with a UHP40 high resolution pole piece operated at 400 kV and with a structural resolution of 1.6 Å. This microscope is used with a Gatan 622 TV system with an image intensifier, coupled to a YAG screen. It was found that the crystals of the quasi crystalline materials here investigated were more sensitive to beam damage using 400 kV as electron accelerating voltage than when using 200 kV. Low dose techniques were therefore applied to avoid damage of the structure.


2019 ◽  
Vol 133 (22) ◽  
pp. 2317-2327 ◽  
Author(s):  
Nicolás Gómez-Banoy ◽  
James C. Lo

Abstract The growing prevalence of obesity and its related metabolic diseases, mainly Type 2 diabetes (T2D), has increased the interest in adipose tissue (AT) and its role as a principal metabolic orchestrator. Two decades of research have now shown that ATs act as an endocrine organ, secreting soluble factors termed adipocytokines or adipokines. These adipokines play crucial roles in whole-body metabolism with different mechanisms of action largely dependent on the tissue or cell type they are acting on. The pancreatic β cell, a key regulator of glucose metabolism due to its ability to produce and secrete insulin, has been identified as a target for several adipokines. This review will focus on how adipokines affect pancreatic β cell function and their impact on pancreatic β cell survival in disease contexts such as diabetes. Initially, the “classic” adipokines will be discussed, followed by novel secreted adipocyte-specific factors that show therapeutic promise in regulating the adipose–pancreatic β cell axis.


2016 ◽  
Vol 21 (6) ◽  
pp. 5-11
Author(s):  
E. Randolph Soo Hoo ◽  
Stephen L. Demeter

Abstract Referring agents may ask independent medical evaluators if the examinee can return to work in either a normal or a restricted capacity; similarly, employers may ask external parties to conduct this type of assessment before a hire or after an injury. Functional capacity evaluations (FCEs) are used to measure agility and strength, but they have limitations and use technical jargon or concepts that can be confusing. This article clarifies key terms and concepts related to FCEs. The basic approach to a job analysis is to collect information about the job using a variety of methods, analyze the data, and summarize the data to determine specific factors required for the job. No single, optimal job analysis or validation method is applicable to every work situation or company, but the Equal Employment Opportunity Commission offers technical standards for each type of validity study. FCEs are a systematic method of measuring an individual's ability to perform various activities, and results are matched to descriptions of specific work-related tasks. Results of physical abilities/agilities tests are reported as “matching” or “not matching” job demands or “pass” or “fail” meeting job criteria. Individuals who fail an employment physical agility test often challenge the results on the basis that the test was poorly conducted, that the test protocol was not reflective of the job, or that levels for successful completion were inappropriate.


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