scholarly journals Medical and dental effects of energy drinks consumption. Literature review.

2018 ◽  
Vol 4 (2) ◽  
pp. 1167-1173
Author(s):  
Katherine Beltrán ◽  
Wilson Cardona
Keyword(s):  
Abdominal Pain ◽  
Citric Acid ◽  
Gastroesophageal Reflux ◽  
Dental Enamel ◽  
Energy Drinks ◽  
Negative Effects ◽  
Mixing Energy ◽  
High Consumption ◽  
Facial Numbness ◽  
Over Time

The energy drinks have undergone exponential hikes over the last years worldwide, in adults, youth, and even children. Among its components can be found: caffeine, guarana, taurine, ging-Seng, L-carnitine, creatinine or glucuronolactone, citric acid and phosphoric acid, among others. A responsible and occasional consumption should not pose major problems, but this is not the case. The medical effects are usually caused by their abuse, like: headaches, palpitations, insomnia, sweating, abdominal pain, vomiting, nausea, gastroesophageal reflux, facial numbness, bloating, tremor, diarrhea and even addiction, among others. While in the dental level, specifically on the dental enamel, the most severe impact is the erosion and the lesser impact is tooth staining, which has not yet been fully investigated, also have been described the development of hypersensitivity. A timely prevention and diagnosis are essential to minimize the damage caused by prolonged use of these products. It is essential to avoid a possible trend or “fad” associated with mixing energy drinks and alcohol and even drugs, of which they are not fully known the possible risks that could potentially cause. Due to its exponential growth it is essential to have an updated knowledge about the consumption of these beverages. The high consumption of energy drinks maintained over time is associated with negative effects at the medical and dental level. Further research is necessary to prevent, treat and rehabilitate the consequences produced by the consumption of these products.

scholarly journals Intestinal obstruction due to small bowel herniation through foramen of Winslow: a case report 

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
P. K. B. S. C. Bandara ◽  
A. M. Viraj Rohana ◽  
Aloka Pathirana
Keyword(s):  
Abdominal Pain ◽  
Small Bowel ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Intestinal Obstruction ◽  
Reflux Disease ◽  
Bowel Loop ◽  
Internal Herniation ◽  
Small Bowel Loop ◽  
Foramen Of Winslow

Abstract Background Intestinal obstruction due to internal herniation of the bowel is a rare clinical entity which is often overlooked in the differential diagnosis of patients with abdominal pain who have no previous history of abdominal surgery. Several sites of bowel internal herniation have been described, amongst which internal herniation through the foramen of Winslow accounts for about 8% of cases. These patients present with nonspecific abdominal pain associated with symptoms of gastroesophageal reflux disease, and hence the diagnosis is often overlooked. The usual symptoms of intestinal obstruction can be delayed, which results in a delay in diagnosis and gangrene of the herniated bowel segment. Abdominal radiographs and computed tomography are helpful in the diagnosis. Open reduction is the management of choice; however, laparoscopic reduction has also been attempted, with good results. Case presentation We report a case of a middle-aged Sri Lankan man who presented with features of gastroesophageal reflux disease, developed features of intestinal obstruction and was found to have a gangrenous small bowel loop which had herniated through the foramen of Winslow. Following needle aspiration and reduction of the herniated small bowel loop, the gangrenous part of the small bowel was resected and an ileoileal anastomosis performed. The large foramen of Winslow was partially closed with interrupted stitches. The patient made an uneventful recovery. Conclusion Since delayed diagnosis of bowel obstruction is detrimental, it is of utmost importance to diagnose it early. Because internal herniation of the small bowel through the foramen of Winslow presents with nonspecific symptoms including features of gastroesophageal reflux disease, as documented in several cases worldwide and also presented by our patient, there should be a high degree of suspicion of internal herniation of the bowel causing bowel obstruction and low threshold for extensive investigation of patients presenting with symptoms of gastroesophageal reflux disease which does not resolve with usual medication.

Recurrent Abdominal Pain During Childhood

1993 ◽  
Vol 14 (8) ◽  
pp. 313-319
Author(s):  
Tim F. Oberlander ◽  
Leonard A. Rappaport
Keyword(s):  
Abdominal Pain ◽  
Recurrent Abdominal Pain ◽  
Underlying Disease ◽  
Careful Examination ◽  
Environmental Aspects ◽  
Successful Management ◽  
Developmental Issues ◽  
Physical Findings ◽  
Over Time

RAP offers a complex and often confusing array of symptoms and diagnostic possibilities. This may be due to its unique age of presentation, its inherent somatic and cognitive developmental issues, or the physiology of abdominal pain itself. A careful examination of the historic and physical findings should produce a therapeutic plan that addresses somatic, psychological, and environmental aspects of the child. This process will avoid overly simplistic and premature misdiagnosis or potentially unnecessary investigations that convey a sense of disinterest, haste, and disbelief in the problem. The successful management of RAP lies in the recognition that serious underlying disease frequently is not present and that time usually is on our side. It is the process of continued and thoughtful evaluation and reassurance over time that counts.

scholarly journals POSTFUNDOPLICATION DYSPHAGIA CAUSES SIMILAR WATER INGESTION DYNAMICS AS ACHALASIA

2016 ◽  
Vol 53 (2) ◽  
pp. 98-102 ◽  
Author(s):  
Roberto Oliveira DANTAS ◽  
Carla Manfredi SANTOS ◽  
Rachel Aguiar CASSIANI ◽  
Leda Maria Tavares ALVES ◽  
Weslania Viviane NASCIMENTO
Keyword(s):  
Surgical Treatment ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Chagas Disease ◽  
Water Volume ◽  
Flow Volume ◽  
Water Ingestion ◽  
Idiopathic Achalasia ◽  
One Year ◽  
Over Time

ABSTRACT Background - After surgical treatment of gastroesophageal reflux disease dysphagia is a symptom in the majority of patients, with decrease in intensity over time. However, some patients may have persistent dysphagia. Objective - The objective of this investigation was to evaluate the dynamics of water ingestion in patients with postfundoplication dysphagia compared with patients with dysphagia caused by achalasia, idiopathic or consequent to Chagas' disease, and controls. Methods - Thirty-three patients with postfundoplication dysphagia, assessed more than one year after surgery, together with 50 patients with Chagas' disease, 27 patients with idiopathic achalasia and 88 controls were all evaluated by the water swallow test. They drunk, in triplicate, 50 mL of water without breaks while being precisely timed and the number of swallows counted. Also measured was: (a) inter-swallows interval - the time to complete the task, divided by the number of swallows during the task; (b) swallowing flow - volume drunk divided by the time taken; (c) volume of each swallow - volume drunk divided by the number of swallows. Results - Patients with postfundoplication dysphagia, Chagas' disease and idiopathic achalasia took longer to ingest all the volume, had an increased number of swallows, an increase in interval between swallows, a decrease in swallowing flow and a decrease in water volume of each swallow compared with the controls. There was no difference between the three groups of patients. There was no correlation between postfundoplication time and the results. Conclusion - It was concluded that patients with postfundoplication dysphagia have similar water ingestion dynamics as patients with achalasia.

scholarly journals Bioadhesive Curcumin-Mediated Photodynamic Inactivation and Its Potential to Cause Undesirable Effects on Dental and Restorative Surfaces

Pharmaceutics ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 1458
Author(s):  
Bárbara Donadon Reina ◽  
Carolina Santezi Neto ◽  
Patrícia Petromilli Nordi Sasso Garcia ◽  
Marlus Chorilli ◽  
Giovana Maria Fioramonti Calixto ◽  
...  
Keyword(s):  
Surface Roughness ◽  
Liquid Crystal ◽  
Tooth Enamel ◽  
Dental Enamel ◽  
Color Stability ◽  
Composite Resins ◽  
Photodynamic Inactivation ◽  
Restorative Material ◽  
Negative Effects ◽  
Restorative Materials

Curcumin-mediated Photodynamic Inactivation (PDI) has shown great potential to disinfect specific sites on tooth enamel but may involve contact with restorative materials. Thus, before use in dentistry, it is necessary to investigate whether the PDI protocol causes undesirable changes in the surfaces of aesthetic restorative materials and dental enamel. This study investigated the effect of PDI mediated by curcumin (CUR) in a liquid crystal precursor system on color stability (ΔE), surface roughness (Ra), and microhardness (kgf) of three different composite resins and bovine dental enamel specimens. The microhardness and roughness readings were performed 60 days after the treatments while the color readings were performed immediately, 24, 48, and 72 h, 7, 14, 21, 30, and 60 days after the treatments. Results showed that CUR mediated-PDI does not seem to have the potential to promote any esthetic or mechanical changes to the surface of tooth enamel and can be applied safely in clinical practice. However, the results on color, roughness, and hardness obtained for composite resins show that some negative effects can be produced, depending on the type of restorative material; more experiments must be performed with different formulations and, perhaps, with lower concentrations of CUR.

scholarly journals Global analysis of DEF damage to concretes with and without fly-ash

2022 ◽  
Vol 15 (3) ◽  
Author(s):  
Nicole Pagan Hasparyk ◽  
Dioice Schovanz ◽  
Francieli Tiecher ◽  
Selmo Chapira Kuperman
Keyword(s):  
Mechanical Properties ◽  
Fly Ash ◽  
Global Analysis ◽  
Physical And Mechanical Properties ◽  
Test Method ◽  
Cement Matrix ◽  
Negative Effects ◽  
Ettringite Formation ◽  
Pozzolanic Cement ◽  
Over Time

Abstract Delayed Ettringite formation (DEF) is an internal expansive reaction that can damage concrete. DEF is strongly influenced by the temperature, above about 60-65°C, and other factors involving cement chemistry especially, but also its physical characteristics. The exposure environment over time also promotes a condition to increase deterioration from DEF. Expansions results from secondary ettringite formation are progressive and can lead concrete to microcracking impacting its performance and durability over time. Several concrete structures are pointed to be severely attacked by DEF, and test method as well a better comprehension on this pathology is necessary to promote specific and proper preventive measures to avoid future damages. Furthermore, compared to alkali-silica reaction, DEF occurs more readily and aggressively, and sometimes prematurely, depending on several factors, such as type of cement, concrete mix design, exposure conditions, among others. This paper involves an overall analysis of the behavior of concretes with two types of Portland cements (High early-strength cement and a Portland pozzolanic cement, with fly-ash) in relation to DEF process. Several data from a laboratory study where DEF was induced through a specific thermal curing procedure are presented and discussed. The analyses involved the assessment of physical, mechanical, and expansive properties besides microstructural monitoring of samples from concretes over time. These experiments allowed detecting high values of expansions from DEF (up to 1.2%) in the concrete without fly ash. The mechanical properties were severely impacted from this deleterious process; as expansions increased, losses in the mechanic and elastic properties were verified. Expansion levels in the order of 0.5% prompted remarkably high reductions and, at about 1% the losses were relevant for both strengths (tensile and compressive) and modulus of elasticity, of 60% and 80%, respectively, in the presence of cement without fly-ash. Concrete microstructure has indicated massive formations of ettringite as well as micro-cracking and the fragility of the cement matrix because of DEF. On the other hand, expansion up to 0.2% did not promote important negative effects on the properties of concrete, especially with the pozzolanic cement tested. Furthermore, an overall approach with several correlations between physical and mechanical properties was taken to obtain different levels of deterioration for a concrete presenting DEF.

STUDY ON EFFECTS OF DISTRUTIVE AGENTS ON THE ARTWORKS

2017 ◽  
Vol 31 (1) ◽  
pp. 75-81
Author(s):  
Valeria Mirela Brezoczki ◽  
◽  
Emese Bonta ◽  
Keyword(s):  
Negative Impact ◽  
Art Museum ◽  
External Factors ◽  
Cultural Value ◽  
Negative Effects ◽  
Active Monitoring ◽  
Baia Mare ◽  
Different Types ◽  
The Impact ◽  
Over Time

The paper describes a series of effects created by the impact of environmental factors on artworks in museums, as well as the way that active monitoring of these destructive agents (temperature and relative humidity) is done. Over time, artefacts exhibited within museums are subject to a series of degradations caused by external factors (air components, humidity, temperature, sunlight, bacteria, molds or fungi etc.), which can leave a negative impact on these goods with cultural value. The main observed negative effects are directly and intimate related to the deterioration of wood sculptures by the occurrence of cracks and the installation of different types of bacteria; the appearance of brownish-red spots on the surface of the paper and the increase in its reliability; various types of corrosion of artworks from different metals; color losses and cracks on paintings etc. The study brings to the fore the damaging effects produced on the different cultural works hosted within the County Art Museum - Art Center Baia Mare.

The Learning Impact of Violent Video Games

2010 ◽  
pp. 312-325
Author(s):  
Alice Ireland ◽  
Nathaniel Payne
Keyword(s):  
Video Games ◽  
Strong Evidence ◽  
Research Evidence ◽  
Aggressive Behaviors ◽  
Negative Effects ◽  
Short Term ◽  
Violent Video Games ◽  
Thinking Processes ◽  
Over Time

There is strong research evidence to suggest that exposure to violent video games is related to an increase in aggressive behaviors in children. Violent video games trigger short-term bursts of aggression, but more importantly they can actually change the user’s thinking processes over time. However, there is also strong evidence to the contrary. This chapter presents an overview of recent evidence for and against the argument on violent games and aggression, together with suggestions for ways that parents can help to mitigate negative effects.

Twenty years of chemotherapy for colorectal cancer (CRC): Progress made, insights gleaned.

2012 ◽  
Vol 30 (4_suppl) ◽  
pp. 596-596
Author(s):  
Irfan Jawed ◽  
Julia Wilkerson ◽  
Austin G. Duffy ◽  
Antonio Tito Fojo
Keyword(s):  
Supportive Care ◽  
Odds Ratio ◽  
Progression Free Survival ◽  
Phase Iii ◽  
Negative Effects ◽  
Phase Ii Trials ◽  
Free Survival ◽  
Large Phase ◽  
And Control ◽  
Over Time

596 Background: The past 20 years have seen progress in CRC therapy with more effective agents and better medical, surgical and supportive care. Methods: We conducted a systematic review of 101 phase III and large phase II trials in CRC to quantify benefit over time with first-line and subsequent therapies. Outcomes examined in the experimental (EA) and control arms (CA) included progression-free survival (PFS), overall response rate (ORR), stable disease (SD), overall survival (OS) and post-treatment survival (PTS). Data were analyzed according to dates of publication and median enrollment. Results: Significant outcomes are reported; most had R2 values > 0.6. OS of EA improved 0.83 mos/yr. Importantly the OS of CA improved 0.58 mos/yr likely reflecting use of experimental therapies in CA in subsequent studies and improvement in CRC care over time as suggested by: (1) modest improvements of PFS: 0.33 [EA] and 0.26 [CA] mos/yr; (2) PTS gains of 0.48 [EA] and 0.29 [CA] mos/yr, accounting for majority of OS gains; and (3) lack of OS improvement in 14 second/subsequent line trials. Using logistic regression to examine all drugs as class predictors of increasing OS, oxaliplatin [OX], bevacizumab [BEV], and irinotecan [IRI] were significant in the EA, but only OX and BEV were significant in the CA. Capecitabine [CAP] and cetuximab/panitumumab [CET/PAN] were not significant in EA or CA, with CAP odds ratio towards null and CET/PAN odds ratio away from null. The lack of IRI effect in CA concurs with observation that only IRI regimens had worse OS in CA compared with EA. The CET/PAN results likely reflect lack of efficacy/harm in patients with WT KRAS tumors. As expected PFS and PTS correlate highly with OS, but importantly ORR had very high correlations with both PFS and OS. SD emerged as an “adverse” outcome, OS decreasing as SD rates increase. Conclusions: OS of CRC patients has improved gradually over past two decades, with gains from chemotherapy but also other factors, such as lead-time bias, more loco-regional approaches and improved supportive care. IRI performed better in EA than in CA. CET/PAN had negative effects in the entire population. In CRC, ORR correlates highly with OS, while SD portends a poor outcome.

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