scholarly journals Extraosseous Ewing’s Sarcoma in Spinal Epidural Space

2018 ◽  
Vol 3 (4) ◽  
pp. 1003-1007
Author(s):  
Luis Espín ◽  
Julio Quispe-Alcocer ◽  
Gabriela Espín ◽  
Jorge Villacís-Sandoval ◽  
Jesús Castro-Viteri

Extraosseous Ewing’s sarcoma belongs to the family of neuroectodermal tumors that de- rive from the neural crest, characteristic of its aggressiveness. Several locations have been described, however, epiduralpresentationisrare. Prognosishasbeenimprovedbynewoncologicalregimensandothertherapeutic targets are being studied.

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Mark Bustoros ◽  
Cheddhi Thomas ◽  
Joshua Frenster ◽  
Aram S. Modrek ◽  
N. Sumru Bayin ◽  
...  

Background. Extraosseous Ewing’s sarcoma in the spinal epidural space is a rare malignancy, especially in adults.Case Presentation. A 40-year-old male presented with back pain and urinary hesitancy. MRI revealed a thoracic extradural mass with no osseous involvement. He underwent surgery for gross total resection of the mass, which was diagnosed as Ewing’s sarcoma. He was subsequently treated with chemoradiotherapy. He remains disease-free 1 year after surgery. Review of the literature indicated only 45 previously reported cases of spinal epidural extraosseous Ewing’s sarcoma in adults.Conclusions. Extraosseous Ewing’s sarcoma in the spinal epidural space is a rare clinical entity that should be included in the differential for spinal epidural masses. Its treatment is multidisciplinary but frequently requires surgical intervention due to compressive neurologic symptoms. Gross total resection appears to correlate with improved outcomes.


2020 ◽  
Vol 15 (4) ◽  
pp. 1068
Author(s):  
Taruna Yadav ◽  
Sarbesh Tiwari ◽  
Jaya Pamnani ◽  
Kartikeya Shukla ◽  
Meenakshi Rao ◽  
...  

1979 ◽  
Vol 51 (1) ◽  
pp. 120-123 ◽  
Author(s):  
Lawrence H. Fink ◽  
Michael W. Meriwether

✓ Primary neoplasms of the spinal epidural space are uncommon. One of the rarest of these is a soft tissue sarcoma indistinguishable from Ewing's sarcoma of the bone. Only 39 such cases have been reported previously, of which only three arose within the epidural space. The authors report an additional case, which presented in an atypical manner, and review the pertinent literature.


2021 ◽  
Vol 21 (2) ◽  
Author(s):  
Adeline Tintila ◽  
Bogdan Doroftei ◽  
Delia Grab ◽  
Gabriela Simionescu ◽  
Emil Anton ◽  
...  

2014 ◽  
Vol 4 ◽  
pp. 6 ◽  
Author(s):  
Stacey K Mardekian ◽  
Ashish Gandhe ◽  
Markku Miettinen ◽  
Svetlana Pack ◽  
Mark T Curtis ◽  
...  

Extraosseous Ewing's sarcoma/peripheral neuroectodermal tumors (ES/PNETs) are rare neoplasms that account for approximately 10%-15% of soft tissue sarcomas in children and 5% of soft tissue sarcomas in adults. Primary spinal, extraosseous, intradural ES/PNETs are even less common. The diagnosis of ES/PNET is extremely challenging, because the tumor can have a nonspecific radiologic appearance, and the histologic features are shared by many other “small round cell tumors.” Thus, ES/PNET should be included in the radiologic and pathologic differential diagnosis, even in older patients and in unusual tumor sites. We report two cases of spinal, extraosseous, intradural ES/PNETs in adults who presented with back pain. Magnetic resonance imaging revealed contrast enhancing, intradural lesions in the area of the conus medullaris. The tumor in Case 1 was partially intramedullary, while the tumor in Case 2 was exclusively extramedullary. In both cases, the radiologic and intraoperative surgical impression favored ependymoma. The diagnosis of ES/PNET was established in both cases by histopathologic, immunohistochemical, and molecular analysis.


2001 ◽  
Vol 45 (3) ◽  
pp. 372-379 ◽  
Author(s):  
P Mukhopadhyay ◽  
M Gairola ◽  
MC Sharma ◽  
S Thulkar ◽  
PK Julka ◽  
...  

Cancer ◽  
1991 ◽  
Vol 68 (3) ◽  
pp. 648-654 ◽  
Author(s):  
Gert-Jan J. L. Kaspers ◽  
Aujo J. P. Veerman ◽  
Wouter Kamphorst ◽  
Michiel van de Graaff ◽  
H. August M. van Alphen

Neurosurgery ◽  
1983 ◽  
Vol 12 (3) ◽  
pp. 337-341 ◽  
Author(s):  
Renato Spaziante ◽  
Enrico de Divitiis ◽  
Arcangelo Giamundo ◽  
Arturo Gambardella ◽  
Bartolo Di Prisco

Abstract Ewing's sarcoma is found exceptionally as a primary epidural tumor of the spine. Four cases have been described in the literature. We describe the fifth case: a 10-year-old boy who underwent operation followed by radiotherapy and chemotherapy. For 1 year he then had a complete remission with no local recurrence and his neurological condition was satisfactory, although metastases developed later. Comparison with the cases described previously shows all five to possess interesting features in common.


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