scholarly journals Ampicillin Trihydrate

2020 ◽  
Author(s):  
Keyword(s):  
Ampicillin Trihydrate

scholarly journals Effects of grinding and drying on the solid-state stability of ampicillin trihydrate.

1984 ◽  
Vol 32 (12) ◽  
pp. 4963-4970 ◽  
Author(s):  
YOSHITERU TAKAHASHI ◽  
KAZUKO NAKASHIMA ◽  
HIROSHI NAKAGAWA ◽  
ISAO SUGIMOTO
Keyword(s):  
Solid State ◽  
Solid State Stability ◽  
Ampicillin Trihydrate

In vivoComparison of Two Galenic Forms of Ampicillin-Trihydrate

Chemotherapy ◽  
1975 ◽  
Vol 21 (1) ◽  
pp. 11-18 ◽  
Author(s):  
J. Pijck ◽  
H. Soep ◽  
J.L. Fraux
Keyword(s):  
Ampicillin Trihydrate

scholarly journals Antibacterial activity of Ampicillin trihydrate formulated in Aluminium-Magnesium Silicate, against <i>Salmonella gallinarum</i>

Health ◽  
2012 ◽  
Vol 04 (09) ◽  
pp. 675-678 ◽  
Author(s):  
Maduike C. O. Ezeibe ◽  
George N. Anosa ◽  
Okechi K. Okorie ◽  
Nnenna P. Elendu-Eleke ◽  
Obianuju N. Okoroafor ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Magnesium Silicate ◽  
Salmonella Gallinarum ◽  
Ampicillin Trihydrate

Synthesis and characterization of novel dimerics-triazine derivatives as potential anti-bacterial agents against MDR clinical isolates

2018 ◽  
Vol 42 (13) ◽  
pp. 10676-10688 ◽  
Author(s):  
Doaa R. Ramadan ◽  
Aly A. Elbardan ◽  
Adnan A. Bekhit ◽  
Ayman El-Faham ◽  
Sherine N. Khattab
Keyword(s):  
Antimicrobial Activity ◽  
Schiff Bases ◽  
Mammalian Cells ◽  
High Selectivity ◽  
Bacterial Activity ◽  
Selectivity Index ◽  
Synthesis And Characterization ◽  
Triazine Derivatives ◽  
Ampicillin Trihydrate

Several dimerics-triazine Schiff bases displayed more potent anti-bacterial activity compared with ampicillin trihydrate. They revealed significantly low MIC values towards the tested MDR strains and showed a high selectivity index towards antimicrobial activity againstK. pneumoniaeandMRSA1compared to mammalian cells.

scholarly journals Chitosan-based nanoparticles sustenance and potentiation of the antibacterial effect of ampicillin against drug resistance among strains of Escherichia coli

Bio-Research ◽  
2020 ◽  
Vol 18 (2) ◽  
Author(s):  
EB Onuigbo ◽  
C Anozie-Ikeanyi ◽  
NE Edeh ◽  
CO Eze ◽  
TH Gugu
Keyword(s):  
Drug Resistance ◽  
Drug Release ◽  
Encapsulation Efficiency ◽  
Antibacterial Effect ◽  
Sodium Tripolyphosphate ◽  
Chitosan Nanoparticles ◽  
In Vitro Drug Release ◽  
E Coli ◽  
Ampicillin Trihydrate

The study seeks to evaluate nanoparticles based on chitosan for enhanced delivery of ampicillin in plasmid-mediated drug resistance. Serial dilutions of a mixed population of E. coli was plated on nutrient agar and streaked on Replica-plate 25 random colonies using MacConkey agar with or without ampicillin (100 µg/ml) daily for 96 h. Nanoparticles were prepared by cross-linking chitosan with sodium tripolyphosphate with ampicillin trihydrate adsorbed. Three different batches were prepared for optimization. The nanoparticles were optimized based on encapsulation efficiency, in vitro drug release, pH stability and microbiological assay using two laboratory strains of E. coli. Increased resistance to ampicillin due to possible plasmid transfer was established in vitro after 96 h. The encapsulation efficiency of the three batches was between 21-57 %. The drug release showed a burst effect and slow extended release over 8 h and reached a peak of about 19 % release at the 6 and 7 h in Batch A, B and C. The pH of the particles was stable over a period of 6 d. The nanoparticles containing only 0.075 mg of ampicillin dropped in an agar well plate inoculated with 1 ml of E. coli J62 lac pro trp hispFlac::Tn3 (AmpR) gave an IZD of ≥ 25 mm. Chitosan nanoparticles holds good potentials in potentiating the antibacterial effect of ampicillin against possible plasmid-mediated drug resistance

A Study of 3-Substituted Benzylidene-1,3-dihydro-indoline Derivatives as Antimicrobial and Antiviral Agents

2009 ◽  
Vol 64 (3-4) ◽  
pp. 155-162 ◽  
Author(s):  
Süreyya Ölgen ◽  
Semiha Özkan
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Bacillus Subtilis ◽  
Klebsiella Pneumoniae ◽  
Antiviral Agents ◽  
Candida Krusei ◽  
Mueller Hinton ◽  
Antibacterial And Antifungal ◽  
Ampicillin Trihydrate

3-Substituted benzylidene-1,3-dihydro-indoline derivatives were tested for their in vitro antibacterial activity against the Gram-negative bacteria Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli, and the Gram-positive bacteria Bacillus subtilis, Staphylococcus aureus, and for their their in vitro antifungal activity against Candida krusei and Candida albicans. The minimum inhibitory concentration (MIC) values were determined by the 2-fold serial dilution technique in Mueller Hinton broth and Sabouraud dextrose agar using antibacterial and antifungal assays, respectively. For comparison of the antimicrobial activity, rifampicin, ampicillin trihydrate, gentamicin sulfate, and ofloxacin were used as reference antibacterial agents, and fl uconazole and amphotericin B were employed as reference antifungal agents. The most active compound 10 showed notable inhibition against Bacillus subtilis, Staphylococcus aureus, and Candida krusei. Compounds 1 and 6 were found slightly effective against Klebsiella pneumoniae and Escherichia coli. In addition, compounds 13 and 14 showed inhibition against Bacillus subtilis and Staphylococcus aureus. Indole derivatives were also tested in vitro for replication of the HepAD38 cell line and compared with lamivudine (3TC, L-2′,3′-dideoxy-3′-thiacytidine). The IC50 values of the compounds were found to be >1000 μM against HBV except for compound 13 which exhibited activity with an IC50 value of 500 μM.

Disposition of ampicillin trihydrate in plasma, uterine tissue, lochial fluid, and milk of postpartum dairy cattle

2014 ◽  
Vol 38 (4) ◽  
pp. 330-335 ◽  
Author(s):  
B. C. Credille ◽  
S. Giguère ◽  
T. W. Vickroy ◽  
H. J. Fishman ◽  
A. L. Jones ◽  
...  
Keyword(s):  
Dairy Cattle ◽  
Uterine Tissue ◽  
Ampicillin Trihydrate

Two-Year Toxicity and Carcinogenicity Studies of Ampicillin Trihydrate and Penicillin VK in Rodents

1989 ◽  
Vol 12 (2) ◽  
pp. 252-257
Author(s):  
JUNE K. DUNNICK ◽  
SCOT L. EUSTIS ◽  
J. E. HUFF ◽  
JOSEPH K. HASEMAN
Keyword(s):  
Ampicillin Trihydrate
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