scholarly journals Sporadic Breast Carcinoma

2020 ◽  
Author(s):  
Keyword(s):  
Breast Carcinoma ◽  
Sporadic Breast Carcinoma

Study of Her-2/neu and TOP2A expression in familial versus sporadic breast carcinoma

2013 ◽  
Vol 12 (1) ◽  
pp. 21-29 ◽  
Author(s):  
Asaad M.S. El-Gerzawy ◽  
Mervat M.S. Al Ansary ◽  
Iman L. Hussein ◽  
Amal M. Mohamed ◽  
Fatma M. Abou El-Kasem ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Sporadic Breast Carcinoma ◽  
Her 2

scholarly journals Expression of Xeroderma Pigmentosum Group G (XPG) in Sporadic Breast Carcinoma

2010 ◽  
Vol 18 (1) ◽  
pp. 37-42 ◽  
Author(s):  
Yoshihisa Koyama ◽  
Masashi Higashimoto ◽  
Kenji Gonda ◽  
Jun Ito ◽  
Nobuhiro Yoshimoto ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Xeroderma Pigmentosum ◽  
Sporadic Breast Carcinoma ◽  
Xeroderma Pigmentosum Group G

scholarly journals A multigene test for the risk of sporadic breast carcinoma

Cancer ◽  
2003 ◽  
Vol 97 (9) ◽  
pp. 2160-2170 ◽  
Author(s):  
David E. Comings ◽  
Radhika Gade-Andavolu ◽  
Lawrence A. Cone ◽  
Donn Muhleman ◽  
James P. MacMurray
Keyword(s):  
Breast Carcinoma ◽  
Sporadic Breast Carcinoma

Aberrant methylation of ATG2B , ATG4D , ATG9A and ATG9B CpG island promoter is associated with decreased mRNA expression in sporadic breast carcinoma

Gene ◽  
2016 ◽  
Vol 590 (2) ◽  
pp. 285-292 ◽  
Author(s):  
Xuemei Zhang ◽  
Chuan Li ◽  
Da Wang ◽  
Qu Chen ◽  
Chang-Long Li ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Mrna Expression ◽  
Cpg Island ◽  
Aberrant Methylation ◽  
Sporadic Breast Carcinoma

scholarly journals A Mouse Mammary Tumor Virus env-Like Exogenous Sequence Is Strictly Related to Progression of Human Sporadic Breast Carcinoma

2011 ◽  
Vol 179 (4) ◽  
pp. 2083-2090 ◽  
Author(s):  
Chiara Maria Mazzanti ◽  
Mohammad Al Hamad ◽  
Giovanni Fanelli ◽  
Cristian Scatena ◽  
Francesca Zammarchi ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Mammary Tumor ◽  
Mouse Mammary Tumor Virus ◽  
Mammary Tumor Virus ◽  
Mouse Mammary Tumor ◽  
Sporadic Breast Carcinoma ◽  
Tumor Virus ◽  
Exogenous Sequence

scholarly journals Analysis of the 10q23 chromosomal region and the PTEN gene in human sporadic breast carcinoma

1999 ◽  
Vol 79 (5-6) ◽  
pp. 718-723 ◽  
Author(s):  
H E Feilotter ◽  
V Coulon ◽  
J L McVeigh ◽  
A H Boag ◽  
F Dorion-Bonnet ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Chromosomal Region ◽  
Pten Gene ◽  
Sporadic Breast Carcinoma

scholarly journals Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast Carcinoma

2003 ◽  
Vol 23 (7) ◽  
pp. 2225-2238 ◽  
Author(s):  
Gustavo Baldassarre ◽  
Sabrina Battista ◽  
Barbara Belletti ◽  
Sanjay Thakur ◽  
Francesca Pentimalli ◽  
...  
Keyword(s):  
Gene Expression ◽  
Breast Carcinoma ◽  
Es Cells ◽  
Embryonic Stem ◽  
Brca1 Gene ◽  
Brca1 Protein ◽  
Protein Levels ◽  
Sporadic Breast Carcinoma

ABSTRACT A drastic reduction in BRCA1 gene expression is a characteristic feature of aggressive sporadic breast carcinoma. However, the mechanisms underlying BRCA1 downregulation in breast cancer are not well understood. Here we report that both in vitro and in vivo HMGA1b protein binds to and inhibits the activity of both human and mouse BRCA1 promoters. Consistently, murine embryonic stem (ES) cells with the Hmga1 gene deleted display higher Brca1 mRNA and protein levels than do wild-type ES cells. Stable transfection of MCF-7 cells with the HMGA1b cDNA results in a decrease of BRCA1 gene expression and in a lack of BRCA1 induction after estrogen treatment. Finally, we found an inverse correlation between HMGA1 and BRCA1 mRNA and protein expression in human mammary carcinoma cell lines and tissues. These data indicate that HMGA1 proteins are involved in transcriptional regulation of the BRCA1 gene, and their overexpression may have a role in BRCA1 downregulation observed in aggressive mammary carcinomas.

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