scholarly journals Simple Endometrial Hyperplasia with Atypia

2020 ◽  
Author(s):  
Keyword(s):  
Endometrial Hyperplasia ◽  
Endometrial Hyperplasia With Atypia

Beyond fertility: The safety of ovarian preservation in women with complex endometrial hyperplasia with atypia

2015 ◽  
Vol 137 ◽  
pp. 82-83
Author(s):  
K.M. Anderson ◽  
N.R. Shah ◽  
M.A. Davis ◽  
L.M. Bean ◽  
C.C. Saenz ◽  
...  
Keyword(s):  
Endometrial Hyperplasia ◽  
Ovarian Preservation ◽  
Endometrial Hyperplasia With Atypia

scholarly journals Prevalence of Coexisting Endometrial Carcinoma in Patients with Preoperative Diagnosis of Endometrial Hyperplasia with Atypia

2020 ◽  
Vol 7 (52) ◽  
pp. 3180-3184
Author(s):  
Divya Sara Raju ◽  
Resmy C. Raveendran ◽  
Ayswariya Manivannan
Keyword(s):  
Endometrial Carcinoma ◽  
Endometrial Hyperplasia ◽  
Early Stage ◽  
Myometrial Invasion ◽  
Cross Sectional ◽  
Endometrial Sampling ◽  
Atypical Endometrial Hyperplasia ◽  
Invasion Stage ◽  
Endometrial Intraepithelial Neoplasia ◽  
Endometrial Hyperplasia With Atypia

BACKGROUND Concurrent carcinoma endometrium occurs in around 40 % of hysterectomy specimen done for premalignant endometrial intraepithelial neoplasia. We intend to study the prevalence of coexisting endometrial cancer in patients who were diagnosed with endometrial hyperplasia with atypia and had undergone hysterectomy. METHODS This cross-sectional study conducted at Government Medical College, Thrissur, included all women with a pre-operative diagnosis of endometrial hyperplasia with atypia (WHO) undergoing hysterectomy during the study period. RESULTS A total of 40 women were found to have atypical endometrial hyperplasia in the study period. The mean age of presentation was 51 ± 2. 7 yrs. and was more common in multiparous postmenopausal women. Postmenopausal bleeding was the most common presenting symptom and more than 50 % of women were overweight. The proportion of concurrent endometrial carcinoma in women with atypical endometrial hyperplasia was found to be 37. 5 %. 93 % of cases with concurrent endometrial carcinoma were of grade I endometrioid type. High risk features were defined as > 50 % myometrial invasion, seen in 47 % patients. Stage 2 endometrial carcinoma was seen in 27 % patients. 53 % patients had less than 50 % myometrial invasion. Stage 1a and 1b endometrial carcinoma was seen in 53 % and 20 % of patients respectively. CONCLUSIONS Large dicer of overlap exists between atypical endometrial hyperplasia (AEH) and early-stage endometrial carcinoma. Therefore, we should recognise the limitation of endometrial sampling in distinguishing between these two groups. KEYWORDS Atypical Endometrial Hyperplasia, Endometrial Carcinoma, Endometrial Sampling

“STUDY OF ENDOMETRIAL PATHOLOGY IN ABNORMAL UTERINE BLEEDING”

2021 ◽  
pp. 1-3
Author(s):  
Neelima Verma ◽  
Suman Lata Verma ◽  
Divya Shukla
Keyword(s):  
Early Diagnosis ◽  
Endometrial Hyperplasia ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Histopathological Analysis ◽  
Common Symptom ◽  
Proliferative Phase ◽  
Number Of Patients ◽  
Endometrial Hyperplasia With Atypia ◽  
Cystic Type

CONTEXT - Histopathological analysis of endometrial samples in various forms of abnormal uterine bleeding in adjunction with clinical history of patient to identify underlying cause of bleeding. This also helps in early diagnosis of premalignant and malignant lesions leading to their proper follow up and improved prognosis. AIMS - Histopathological analysis of causes of abnormal uterine bleeding with their clinical correlation. SETTINGS AND DESIGN -A prospective observational study MATERIAL AND METHODS - This study was done in department of pathology, GSVM medical college, Kanpur. This was a prospective study from year 2017-2018. A total of 300 cases were studied. Specimen received were xed in 10% formalin, processed and sections of 3-4 micron were prepared, stained with H and E. Histopathological examination was done. RESULTS - It was observed that the highest number of patients were between 41-50 years of age. (44.33%). Menorrhagia is the most common symptom accounting for 135 (45%) patients followed by metrorrhagia accounting for 135 (45%) patients and hypomenoorhea is the least common complaint. It was observed that there were signicantly higher number of patients with proliferative phase – 68 (22.67%) and in endometrial hyperplasia 35 (33.66%) patients. The least common cause were endometrial polyp, seen in 4 (1.33%) patients, gestational endometrium and gestational trophoblastic tumor accounted for 2 ( 0.67%) patients. In patients who presented with metrorrhagia, secretory phase endometrium was the most common histopathological nding accounting for 34.62% followed by proliferative phase. In cases of endometrial hyperplasia, 28 (80%) cases were simple cystic type, 5 ( 14.29%) cases were of simple endometrial hyperplasia with atypia and complex endometrial hyperplasia with atypia was found in 2(5.71%) cases. Among cases of endometrial hyperplasia, 28 (80%) cases were simple cystic type, 5 ( 14.29%) cases were of simple endometrial hyperplasia with atypia and complex endometrial hyperplasia with atypia was found in 2(5.71%) cases. Endometrial carcinoma is commonest complain in 51-60 years and >60 years age group. CONCLUSION - Histopathological analysis of AUB causes helps in identifying the cause and early diagnosis of premalignant and malignant cases.

Endometrial Hyperplasia with Atypia

2013 ◽  
pp. 214-214
Author(s):  
Anthony E. Dragun ◽  
Paul J. Schilling ◽  
Tod W. Speer ◽  
Feng-Ming Kong ◽  
Jingbo Wang ◽  
...  
Keyword(s):  
Endometrial Hyperplasia ◽  
Endometrial Hyperplasia With Atypia
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